Nathan Reticker-Flynn
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retickerflynn.bsky.social
Nathan Reticker-Flynn
@retickerflynn.bsky.social
Tumor Immunologist. Assistant Prof at Stanford. Metastasis. Lymphocytes. Tolerance. Immunotherapy. Evolution. www.retickerflynnlab.com
Lymph node metastasis is almost always synonymous with cancer progression, but in this fantastic study from @ubellackerlab.bsky.social, they reveal that it also imparts a key metabolic vulnerability: FSP1 dependency. Congrats Jess and @mariopalma.bsky.social!
Excited to share our work @nature.com! Postdoc @mariopalma.bsky.social, with major contributions from @retickerflynn.bsky.social and collaborators, discovered melanoma cells in lymph nodes gain a targetable FSP1 dependency that limits progression. #TeamFSP1

www.nature.com/articles/s41...
Lymph node environment drives FSP1 targetability in metastasizing melanoma | Nature
www.nature.com
November 5, 2025 at 10:27 PM
Reposted by Nathan Reticker-Flynn
Evolution Under Therapy: Resistance Mechanisms—
Andrew J. Aguirre, Nathan Reticker-Flynn, Susan M. Rosenberg, and Kathleen Burkhardt will address this topic in a plenary at the AACR Special Conference on Cancer Evolution (Dec 4-6; Albuquerque).
buff.ly/4ecfgxE
#AACRevol25 @retickerflynn.bsky.social
October 21, 2025 at 3:11 PM
Reposted by Nathan Reticker-Flynn
Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV
August 18, 2025 at 3:42 PM
Interested in studying lymph node metastasis? Check out our protocol by Cort Breuer out today in @natprot.nature.com
bsky.app/profile/nat...
Nature Protocols (@natprot.nature.com)
New Article! Spontaneous and experimental models of lymph node metastasis https://bit.ly/4fzWoAj
bsky.app
August 13, 2025 at 3:20 PM
Our lab has an opening for a new Research Assistant (LSRP) starting this Summer/Fall. If you're interested in joining a vibrant community working at the interfaces of cancer metastasis and adaptive immunity, apply here:
careersearch.stanford.edu/jobs/life-sc...
Life Science Research Professional 1 in School of Medicine, Stanford, California, United States
Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects....
careersearch.stanford.edu
April 1, 2025 at 7:28 PM
Reposted by Nathan Reticker-Flynn
Excited to share this work from the Garcia Lab out today in @naturecomms.bsky.social! We engineer "cytokine adaptors", molecular immune switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS
Redirecting immune signaling with cytokine adaptors
Nature Communications - Cytokines are immune signaling molecules that are frequently dysregulated in disease. Here, the authors create engineered cytokine ‘adaptors,’ molecular switches...
rdcu.be
March 12, 2025 at 1:35 AM
First Bluesky post! If you're interested in hearing about our work, check out this seminar in a couple weeks.
Calling all metastasis researchers - don't forget to join us for our next webinar on Dec 3rd as Dr. Nathan Reticker-Flynn discusses "Lymph node metastasis and the orchestration of adaptive immune responses to tumors". Sign-up today! us02web.zoom.us/webinar/regi...
November 21, 2024 at 10:19 PM