Peter Rupprecht
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ptrrupprecht.bsky.social
Peter Rupprecht
@ptrrupprecht.bsky.social
Junior group leader in neuroscience - calcium imaging, ephys, plasticity, microscopy, neurons & astrocytes, data analysis. PhD with Rainer Friedrich, postdoc with Fritjof Helmchen. https://www.gcamp6f.com/
But I believe that post-publication reviews, or the suggestions that you've made, or simply transparent open reviews, which is used by many journals already, are a good way to read papers better and more efficiently. And this is a culture change that has already taken place during the last decade...
November 21, 2025 at 10:39 AM
I don't think there is a way around properly reading the literature. How could we design science experiments, if the knowledge that we need for their design is somewhere in a database or LLM, but not in our heads?
November 21, 2025 at 10:38 AM
Good point! But already now, everybody can contribute to post-publication peer review right now, no need for a centralized structure. I regularly write such reviews on my blog: gcamp6f.com/category/rev...
The idea is not new, see the "peeriodicals" by Romain Brette:
peeriodicals.com/peeriodicals...
Peeriodicals
Theory of spike initiation, sensory systems, autonomous behavior, epistemology
peeriodicals.com
November 20, 2025 at 8:59 PM
If you don't learn how to write, then you don't learn how to think.
November 15, 2025 at 3:52 PM
Looks like a 1:1 copy of the Cambridge Technology 8 kHz scanner. Did you notice any differences? Or have they simply licensed the technology from the existing scanner?
October 22, 2025 at 7:58 PM
It's a great paper - congrats!
October 3, 2025 at 8:25 PM
This objective was designed for 2P imaging. For 1P imaging, I believe that there are still some technical problems to be solved. Perhaps @voigtvision.bsky.social or @nvladimus.bsky.social can tell you more!
September 29, 2025 at 9:15 AM
I'm using it mostly for 2P imaging, but it should also be relevant for expansion microscopy: Olympus XLPLN10XSVMP with NA 0.6, WD 8 mm: evidentscientific.com/en/objective...
Objective Finder | Evident Scientific | Olympus
Select the right lens for your application from our broad line of Olympus microscope objectives.
evidentscientific.com
September 28, 2025 at 6:22 PM
I also wonder whether you have observed any signs of cytotoxicity or fluorophore aggregates?
July 31, 2025 at 8:06 PM
This OCaMP sensor looks quite promising! Looking forward to trying it out!
July 31, 2025 at 8:01 PM
Thanks, it looks very interesting!

The first comment of reviewer #1 is also "interesting", asking for the "connectome" of VIP neurons for the revised manuscript ;-)
July 3, 2025 at 7:17 PM