#SingleCell preprints
prepub-singlecell.bsky.social
#SingleCell preprints
@prepub-singlecell.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square
regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)'

If you have suggestions, please get in contact with @willmacnair :)
A Multi-omic Atlas of Human Choroid Plexus in Alzheimer's Disease #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.23.690014v1
November 25, 2025 at 5:01 PM
Deciphering HTLV-1-associated Lung Pathology through Integrated in vitro and Multi-cohort Multi-omics Analysis: Inflammation, Monocyte Recruitment and Differentiation Triggered by HTLV-1-exposed Alveolar Epithelial Cells #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-8051355/latest
November 25, 2025 at 5:01 PM
Dopamine receptor 1-expressing cells in the ventral hippocampus encode cocaine-context associations #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-8079719/latest
November 25, 2025 at 5:01 PM
FKBP10 as a Prognostic Biomarker and Therapeutic Target in Hepatocellular Carcinoma #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7897879/latest
November 25, 2025 at 5:01 PM
Cis-TERN: a graph-based method to integrate single-cell chromatin accessibility with gene expression data to infer the pseudotime ordering of cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.21.689849v1
November 25, 2025 at 5:00 PM
Molecular mechanism decipher of Alzheimer's disease based on single-cell RNA-seq information #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.22.689872v1
November 25, 2025 at 5:00 PM
Developmental and transcriptional programs that define the initiation of the forelimb #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.23.689776v1
November 25, 2025 at 5:00 PM
Phylogenetic and phylodynamic approaches to understanding the evolution of non-small cell lung cancer using single-cell sequencing #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-8017001/latest
November 25, 2025 at 8:01 AM
Summary data-based mendelian randomization and single-cell RNA sequencing analyses identify key genes associated with ubiquitination in prostate cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7723484/latest
November 25, 2025 at 8:01 AM
Lactylation drives tumor microenvironment remodeling and immune evasion in esophageal cancer revealed by multiomics and single cell transcriptomics #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7809424/latest
November 25, 2025 at 8:01 AM
Multi Omics and Mechanistic Investigation Reveals CBFB as a Prognostic Biomarker in Gastric Cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7940951/latest
November 25, 2025 at 8:01 AM
LLM4Cell: A Survey of Large Language and Agentic Models for Single-Cell Biology #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2510.07793
November 25, 2025 at 8:01 AM
Structured Matching via Cost-Regularized Unbalanced Optimal Transport #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.19075
November 25, 2025 at 8:01 AM
CFM-GP: Unified Conditional Flow Matching to Learn Gene Perturbation Across Cell Types #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2508.08312
November 25, 2025 at 8:00 AM
SynCell: Contextualized Drug Synergy Prediction #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.17695
November 25, 2025 at 8:00 AM
Accurate Probabilistic Reconstruction of Cell Lineage Trees from SNVs and CNAs with ScisTreeCNA #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.21.689819v1
November 25, 2025 at 8:00 AM
Inferring virtual cell environments using multi-agent reinforcement learning #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.21.689815v1
November 25, 2025 at 8:00 AM
Uncovering structural determinants of peptide recognition by public and private T-cell receptors #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.23.690020v1
November 25, 2025 at 8:00 AM
Biophysical constraints on mRNA decay rates shape macroevolutionary divergence in steady-state abundances #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.24.690267v1
November 25, 2025 at 8:00 AM
Determining gene specificity from multivariate single-cell RNA sequencing data #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.21.689845v1
November 24, 2025 at 5:00 PM
A cross-species spatial transcriptomic atlas of the human and non-human primate basal ganglia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.22.688128v1
November 24, 2025 at 5:00 PM
Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.19.689393v1
November 24, 2025 at 5:00 PM
Single-cell disentangled representations for perturbation modeling and treatment effect estimation #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.21.689783v1
November 24, 2025 at 5:00 PM
Genetic-exposome axis orchestrates cardiac motion patterns #SingleCell 🧪🧬🖥️
http://medrxiv.org/cgi/content/short/2025.11.22.25340784v1
November 24, 2025 at 8:01 AM
A Hybrid Computational Intelligence Framework for scRNA-seq Imputation: Integrating scRecover and Random Forests #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.16923
November 24, 2025 at 8:00 AM