Kehari
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postvulpine.bsky.social
Kehari
@postvulpine.bsky.social
180 followers 340 following 230 posts
Born vulpine. Evolved beyond the bounds of her physical shell. Still uses that shape out of nostalgia, except when she doesn't. Mostly furry art/porn and socially/politically leftist reposts. Here there be NSFW. 18+!
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Reposted by Kehari
sailorrooscout.bsky.social
Their efficacy was confirmed against LIVE viruses including Ebola, Marburg, Nipah, Hendra, SARS-CoV, SARS-CoV-2 (COVID-19), AND Middle East Respiratory Syndrome (MERS).

The study has been published in Science Advances. YES, it is PEER-REVIEWED.
• www.science.org/doi/10.1126/...

🧪🧵⬇️
ABSTRACT Viral pandemics continue to threaten global health and economic stability. Despite medical advances, the absence of broad-spectrum antivirals (BSAs) prevents rapid responses to emerging viral threats. This is largely due to the lack of universal drug targets across diverse viral families and high variability among viral proteins. In this study, we evaluated 57 synthetic carbohydrate receptors (SCRs) for antiviral activity in cellulo using pseudotyped virus particles (PVPs) from six high-risk viruses across three families: Paramyxoviridae, Filoviridae, and Coronaviridae. Four SCRs inhibited all tested PVPs, and their efficacy was confirmed against live viruses including SARS-CoV-2, MERS-COV, EBOV, MARV, NiV, and HeV. Notably, SCR005 and SCR007, which exhibited minimal toxicity, significantly reduced SARS-CoV-2 infection in a severe animal model with a single dose. Mechanistic studies suggested that SCRs bind viral envelope N-glycans, blocking viral attachment and/or fusion. These results identify conserved viral N-glycans as promising BSA targets and establish SCRs as candidate prophylactic agents against enveloped viruses with pandemic potential.
November 28, 2025 at 5:02 PM
postvulpine.bsky.social
What an absolutely perfect picture for that link. I can practically hear the *gulp*.
November 27, 2025 at 2:41 AM
postvulpine.bsky.social
Sleepy Don
November 26, 2025 at 3:04 AM
Reposted by Kehari
trans.bsky.social
anyone defending nazis is doing so because:
Nazi ain't got no humanity.
October 22, 2025 at 1:40 AM
postvulpine.bsky.social
The tone of this thing is right up there with the news stories that go, "Hey check out this heartwarming story of how a little girl sold lemonade on the corner to help her mom afford a heart transplant." Can't see the forest for all the trees in the way.
October 6, 2025 at 3:12 AM
postvulpine.bsky.social
Good news doesn't get clicks.
September 29, 2025 at 1:55 PM