@PoratShliomLab
@poratshliomlab.bsky.social
Cell Biologist and microscopist. My lab
@NCIResearchCtr focuses on mitochondria, metabolism, and liver cancer. Views are my own #cellbiology #microscopy
@NCIResearchCtr focuses on mitochondria, metabolism, and liver cancer. Views are my own #cellbiology #microscopy
Congratulations, Ivy!!
May 20, 2025 at 11:26 PM
Congratulations, Ivy!!
Thank you @ivyxiong.bsky.social for being part of the team!
May 9, 2025 at 5:23 PM
Thank you @ivyxiong.bsky.social for being part of the team!
Thank you, Jonny!
December 13, 2024 at 11:15 PM
Thank you, Jonny!
Fits nicely with what you showed in brown adipose.
December 13, 2024 at 11:07 AM
Fits nicely with what you showed in brown adipose.
Thank you, Marc!
December 13, 2024 at 11:06 AM
Thank you, Marc!
Thank you, Doug!
December 13, 2024 at 3:32 AM
Thank you, Doug!
Thank you, Sarah! Your insights into PLIN5 functions were invaluable!
December 13, 2024 at 12:44 AM
Thank you, Sarah! Your insights into PLIN5 functions were invaluable!
Fantastic teamwork in the Porat-Shliom lab AND the amazing resources at the IRP at NCI!
December 12, 2024 at 5:19 PM
Fantastic teamwork in the Porat-Shliom lab AND the amazing resources at the IRP at NCI!
10. In WD conditions, increasing PLIN5 levels enables hepatocytes to regulate the proportion of mitochondria bound to LDs versus those free in the cytosol, facilitating more efficient management of lipid overload.
December 12, 2024 at 5:16 PM
10. In WD conditions, increasing PLIN5 levels enables hepatocytes to regulate the proportion of mitochondria bound to LDs versus those free in the cytosol, facilitating more efficient management of lipid overload.
9. This could explain how, under nutritional deficits, mito simultaneously supports lipid oxidation for ketogenesis while promoting TG synthesis and storage to mitigate lipotoxicity. READ ON...
December 12, 2024 at 5:16 PM
9. This could explain how, under nutritional deficits, mito simultaneously supports lipid oxidation for ketogenesis while promoting TG synthesis and storage to mitigate lipotoxicity. READ ON...
8. During nutritional stress like fasting, the spatial division is lost, in part due to the upregulation of PLIN5 and its phosphorylation status, leading to the emergence of both types of mitochondria in most hepatocytes. READ ON...
December 12, 2024 at 5:16 PM
8. During nutritional stress like fasting, the spatial division is lost, in part due to the upregulation of PLIN5 and its phosphorylation status, leading to the emergence of both types of mitochondria in most hepatocytes. READ ON...