Pierce Lab
pierce-lab.bsky.social
Pierce Lab
@pierce-lab.bsky.social
Computational structural biology and AI at the University of Maryland and Institute for Bioscience and Biotechnology Research. Decoding and engineering immune recognition.
#AlphaFold 2 (via TCRmodel2) and AlphaFold3 were both tested for modeling of these new complex structures, and both were able to model them accurately. However, modeling of additionally structurally uncharacterized complexes led to low confidence scores, indicating room for improvement.
November 22, 2024 at 8:57 PM