Pia Reichl
@pia-rei.bsky.social
PhD student interested in the interplay of DNA repair and blood development @ Chapman Lab, Uni of Oxford
My PhD work is out as a preprint! Have a read 😊👇🏻
New lab preprint! ERCC6L2 disease is a recessive bone marrow failure syndrome caused by mutations in the putative DNA helicase ERCC6L2. Using mouse genetics, biochemistry and AF3 we uncover ERCC6L2-MRI as a KU-regulatory complex stimulating NHEJ at staggered DSBs: www.biorxiv.org/content/10.1...
The ERCC6L2-MRI-KU complex coordinates NHEJ at staggered DNA double-strand breaks
ERCC6L2 disease is a recessive bone marrow failure (BMF) syndrome caused by mutations in the SNF2-like putative DNA helicase ERCC6L2. While implicated in DNA replication, double strand break (DSB) rep...
www.biorxiv.org
December 2, 2025 at 12:27 PM
My PhD work is out as a preprint! Have a read 😊👇🏻
Reposted by Pia Reichl
Few better ways to end the year with the team than over a few pints (& mini Guinness’s) in the @StarPubOxford
December 19, 2024 at 9:36 AM
Few better ways to end the year with the team than over a few pints (& mini Guinness’s) in the @StarPubOxford