Philip Gunkel
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philipgunkel.bsky.social
Philip Gunkel
@philipgunkel.bsky.social
Postdoc at the MPI for Multidisciplinary Sciences in Göttingen; Research focus: the nuclear pore complex (NPC) and in particular the nuclear basket - composition, function and beyond...
Reposted by Philip Gunkel
We are very excited that our work on Torsins, dystonia and NE membrane fusion is out on bioRxiv: doi.org/10.1101/2025...

Fantastic collaboration with Madhav Jagannathan and the labs of Gautam Dey and Stefano Vanni!
Dystonia-associated Torsins sustain CLCC1 function to promote membrane fusion of the nuclear envelope for NPC biogenesis
DYT1 early-onset dystonia is a severe, incurable disorder of the central nervous system caused by mutations in the gene encoding Torsin1A (Tor1A, DYT1). Torsins are ER-resident AAA+-ATPases implicated...
doi.org
November 10, 2025 at 8:54 AM
Reposted by Philip Gunkel
Congratulations to Dirk Görlich and Steven L. McKnight, 2025 #LaskerAward winners! - “for discoveries that exposed the structures and functions of low-complexity domains within protein sequences” 🧪
@mpi-nat.bsky.social
#Lasker2025 #LaskerLaureate #structuralbiology #phaseseparation
September 11, 2025 at 1:07 PM
Only a few days left to register...
Registration is open for a great meeting in Potsdam, Germany (July 23-27) ... for everyone interested in the biology of the nuclear envelope and related topics (events.gwdg.de/event/1012/)
April 28, 2025 at 8:03 PM
Reposted by Philip Gunkel
Governed by surface amino acid composition: HIV capsid passage through the NPC barrier https://www.biorxiv.org/content/10.1101/2025.03.13.643050v1
March 14, 2025 at 6:30 AM
Registration is open for a great meeting in Potsdam, Germany (July 23-27) ... for everyone interested in the biology of the nuclear envelope and related topics (events.gwdg.de/event/1012/)
January 28, 2025 at 9:21 PM
Reposted by Philip Gunkel
📣 Join us for #EESNucleus 🧬

Explore the dynamic world of the nucleus at the new EMBO | EMBL Symposium. From nuclear mechanics to pathomechanisms, join the conversation shaping modern cell biology.

🗓️ 18 – 21 November 2025
📥 Submit your abstract by 26 August

👉 https://s.embl.org/ees25-07-bl
January 23, 2025 at 11:58 AM