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phdpetrelli.bsky.social
@phdpetrelli.bsky.social
This is a great work indeed!!!
May 17, 2025 at 4:28 PM
Reposted
Hiring! Postdoc position in Human Metabolism!
Join us to explore the metabolic underpinnings of human brain & behavior; focusing on anxiety & motivation
Outstanding interdisciplinary environment @epfl-brainmind.bsky.social at EPFL in Lausanne Switzerland
Info here: www.fens.org/careers/job-...
Postdoctoral Position in Human Metabolism, Mitochondria & Behavior at EPFL - Federation of European Neuroscience Societies
www.fens.org
April 1, 2025 at 4:37 PM
Reposted
🚨The first #preprint of the #FalconeLab is OUT!🥹🚨

We found that varicose-projection astrocytes are not a physiological type of #astrocytes but they are rather associated with neuropathology.

Read more here, feedback is welcome!!

More details👇👇
1/
www.biorxiv.org/content/10.1...
Varicose-projection astrocytes: a reactive phenotype associated with neuropathology
Glial cells are fundamental for the pathophysiology of all neurological disorders. Astrocytes, the primary homeostatic cells of the central nervous system (CNS), exhibit species-specific characteristi...
www.biorxiv.org
March 18, 2025 at 3:42 PM
Reposted
🚀 Think all white matter (WM) astrocytes are the same? Think again! 🌟 Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. 🧠

www.nature.com/articles/s41...
Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter - Nature Neuroscience
White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in cerebellar WM, suggestin...
www.nature.com
February 24, 2025 at 4:06 PM
Reposted
Trying my best to focus on some positive science content. We feel so grateful to have our work highlighted on the cover of @naturecellbiology.bsky.social!

This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz
February 18, 2025 at 12:07 PM
Reposted
New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! 🔬 🐭 🧠

www.nature.com/articles/s41...
Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function - Nature Communications
Remyelination can restore neural function. Here, the authors characterize the drivers and limits of endogenous remyelination and explore a therapy that rescued remyelination deficits and accelerated n...
www.nature.com
January 18, 2025 at 6:41 PM
Reposted
Check this great paper from the Kononenko lab at @cecad.bsky.social

"Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity"
www.nature.com/articles/s42...
Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - Nature Metabolism
Tutas et al. show an unconventional role for autophagy in the regulation of glycolytic flux in cerebellar Purkinje cells by maintaining the levels of the glucose transporter GLUT2.
www.nature.com
January 18, 2025 at 10:14 AM
Reposted
⭐️ Wang et al.: Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain ⭐️
www.nature.com/articles/s41...
Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain - Nature Biotechnology
Transplantation of glia-enriched organoids into the mouse brain enables the study of astrocyte subtypes.
www.nature.com
January 18, 2025 at 7:37 AM
Reposted
Molecular dynamics of neural stem cells (NSCs) and their surrounding niche in the #aging mouse #hippocampus using multimodal transcriptomics 🧪🧠

www.nature.com/articles/s41...
Multimodal transcriptomics reveal neurogenic aging trajectories and age-related regional inflammation in the dentate gyrus - Nature Neuroscience
Multimodal transcriptomics unveil the molecular dynamics of neural stem cells and their surrounding niche in the aging mouse hippocampus and provide a resource to understand age-related molecular chan...
www.nature.com
January 10, 2025 at 4:59 PM