PessoaBrain
pessoabrain.bsky.social
PessoaBrain
@pessoabrain.bsky.social
Luiz Pessoa, University of Maryland, College Park
Neuroscientist interested in cognitive-emotional brain
Author of The Entangled Brain, MIT Press, 2022
Author of The Cogitive-Emotional Brain, MIT Press, 2013
Neuroscience & Philosophy Salon (YouTube)
𝗖𝗼𝗻𝘁𝗿𝗼𝗹 𝗮𝗻𝗱 𝘁𝗵𝗲 𝗹𝗶𝗺𝗶𝘁𝘀 𝗼𝗳 𝗺𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝘁𝗶𝗰 𝗲𝘅𝗽𝗹𝗮𝗻𝗮𝘁𝗶𝗼𝗻
This paper from Biological Theory looks great (but haven't read it yet).
link.springer.com/article/10.1...
#philosophy #biology
November 24, 2025 at 5:37 PM
𝗖𝗼𝗴𝗻𝗶𝘁𝗶𝘃𝗲 𝗳𝗹𝗲𝘅𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗮𝗻𝗱 𝘀𝘁𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘁𝗵𝗲
𝗹𝗲𝗻𝘀 𝗼𝗳 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝗮𝗹 𝘀𝘆𝘀𝘁𝗲𝗺𝘀
"...trade-off between cognitive flexibility and stability inherent to dynamical system models of varying complexity."
by S Musslick and A Bizyaeva
#neuroskyence
doi.org/10.1016/j.co...
November 22, 2025 at 6:43 PM
If you're thinking of academia in your future, you had better love writing and, yes, rewriting...
November 21, 2025 at 7:16 PM
𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗶𝗺𝗽𝗹𝗲𝗺𝗲𝗻𝘁 𝗱𝗲𝗰𝗶𝘀𝗶𝗼𝗻𝘀 𝗶𝗳 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝗻𝗼 "𝗰𝗲𝗻𝘁𝗿𝗮𝗹 𝗲𝘅𝗲𝗰𝘂𝘁𝗶𝘃𝗲" (𝗮𝗸𝗮 𝗵𝗼𝗺𝘂𝗻𝗰𝘂𝗹𝘂𝘀)?
Via Decision Formation Through Multi-Area Population Dynamics
Excellent short review.
doi.org/10.1523/JNEU...
#neuroskyence
November 20, 2025 at 8:37 PM
𝗔𝗿𝗼𝘂𝘀𝗮𝗹 𝗮𝘀 𝗮 𝘂𝗻𝗶𝘃𝗲𝗿𝘀𝗮𝗹 𝗲𝗺𝗯𝗲𝗱𝗱𝗶𝗻𝗴 𝗳𝗼𝗿 𝘀𝗽𝗮𝘁𝗶𝗼𝘁𝗲𝗺𝗽𝗼𝗿𝗮𝗹 𝗯𝗿𝗮𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀
"...support hypothesis that spontaneous spatially structured fluctuations in brain-wide physiology on timescales of seconds ... are in large part expressions of lowdimensional, organism-wide dynamical system"
doi.org/10.1038/s415...
November 16, 2025 at 4:25 PM
𝗕𝗿𝗮𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗮𝗻𝗱 𝘀𝘁𝗮𝘁𝗲𝘀
Not a new one but worth a read
dx.doi.org/10.1016/j.co...
#neuroskyence
November 12, 2025 at 6:17 PM
AI has come an enormous way since the early days...
Amazing precision and scholarly knowledge.
GoaLPleation for one is just around the corner in neuroscience research 😱
#neuroskyence
November 11, 2025 at 3:55 PM
𝗜𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗮 𝗰𝗼𝗺𝗽𝗹𝗲𝘅 𝗻𝗲𝘁𝘄𝗼𝗿𝗸?
In a sense yes, but does network science help us understand the brain as a complex system? Intriguing paper.
If anything the paper has 800+ refs!
#neuroskyence #complexsystems
doi.org/10.1016/j.pl...
November 10, 2025 at 6:14 PM
Hidden Markov Models
Speaking of HMMs, really enjoyed this paper on dynamics underlying resting state and other conditions. The idea of a baseline state from which excursions lead to more integrated states is really interesting.
doi.org/10.7554/eLif...
#neuroskyence
November 9, 2025 at 3:03 PM
Now that we have Hidden Markov Models do we still need correlation matrices?? 😀
For example, this looks cool.

(I'm aware that HMMs are not new, I played with them in grad school...)
doi.org/10.1016/j.is...
#neuroskyence
November 8, 2025 at 4:12 PM
**CORRECTION of link**

Neurocomputational architecture for syntax/language
Neuro & Philo Salon: join our discussion with
@elliot-murphy.bsky.social with commentaries by @wmatchin.bsky.social and @sandervanbree.bsky.social
Nov 5, 10:30 am eastern US
Registration:
umd.zoom.us/meeting/regi...
November 4, 2025 at 5:04 PM
𝗡𝗼𝗻𝗶𝗻𝘃𝗮𝘀𝗶𝘃𝗲 𝘀𝘂𝗽𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝗼𝗳 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲𝘀 𝘁𝗼 𝘁𝗵𝗿𝗲𝗮𝘁 𝘂𝘀𝗶𝗻𝗴 𝗳𝗼𝗰𝘂𝘀𝗲𝗱 𝘂𝗹𝘁𝗿𝗮𝘀𝗼𝗻𝗶𝗰 𝘄𝗮𝘃𝗲𝘀
That's noninvasive! And the bed nucleus of the stria terminalis is small.
Let's see what people think.
doi.org/10.1523/JNEU...
#neuroskyence
November 2, 2025 at 5:47 PM
And now the best brain region
October 31, 2025 at 2:54 PM
Looks like it
October 31, 2025 at 2:53 PM
Common circuit?
October 31, 2025 at 2:31 PM
Brain Dynamics and Flexible Behaviors
@lucinauddin.bsky.social presenting at the University of Maryland
October 31, 2025 at 2:24 PM
**Discovering network dynamics**
One more on estimating dynamics of complex systems, this time with symbolic regression
doi.org/10.1038/s435...
October 30, 2025 at 4:57 PM
Congrats, great choices for Cogneuro research:
October 29, 2025 at 2:02 PM
*Neurocomputational architecture for syntax/learning*

Neuroscience & Philo Salon: join our discussion with @elliot-murphy.bsky.social with commentaries by @wmatchin.bsky.social and @sandervanbree.bsky.social
Nov 5, 10:30 am eastern US
Register:
umd.zoom.us/my/luizpesso...
#neuroskyence
October 27, 2025 at 4:52 PM
Who says current AI is not great?
Excellent for solving Latex questions that would take me a long time to figure out myself (possibly never...). Easy to place a vertical line to highlight paper sections that need work 🤣
October 19, 2025 at 9:08 PM
*The Animal and the Thinker*
by the amazing neuroscientist John Duncan, U of Cambridge.
Haven't read it but looks really interesting.
#neuroskyence
October 19, 2025 at 6:22 PM
Receptive field properties don't change but
October 17, 2025 at 2:48 PM
The feedback is highly organized anatomically
October 17, 2025 at 2:33 PM
The feedback
October 17, 2025 at 2:24 PM
Feedback in the brain

Looking forward to this one but thought the thalamus was basically a relay station... 😅
October 17, 2025 at 2:14 PM