The new DSSP version 4 uses mmCIF as its primary format and extends secondary structure detection to include left-handed polyproline II (κ) helices, common motifs that contribute to protein folding and stability.

Full announcement: www.ebi.ac.uk/pdbe/news/pd...

#PDBe #DSSP #ProteinStructure

The effort adopts community tools like FindGeo (MetalPDB) and MetalCoord (CCP4).
Details and example files are available at wwPDB.org
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For queries: [email protected]

This update will affect ~900 metal-containing CCDs and ~13,000 PDB entries, with public release planned for Q3 2026.
It includes improved charge standardisation, metal coordination and π-bond annotation, and geometry information.

Your direct links to structures have a new format.

Old: alphafold.com/entry/P40763
New: alphafold.com/entry/AF-P40...

Simply add 'AF-' and '-F1' to the UniProt ID. Update your bookmarks and code!

MSAs are listed on each entry page on the top right-hand side in a drop-down list. Bulk access is not currently available.

Want exact accessions per category?
FTP: ftp.ebi.ac.uk/pub/database...
Files: “diffs.ndjson.gz” (per-release diff), “accession_ids.csv” (current v6 set).
See “README.txt” there for field definitions.

“Added/Removed” track UniProt additions/archives, and 40,054 isoforms added
“Changed” = sequence changed (not metadata).
“Unchanged” = metadata updated to current UniProt; entries relabelled v6.

💬 Your responses will help guide future improvements to the tool.
🙏 Thank you for helping us make PDBePISA more useful for the community!

📍 Where to find the PDBe Complex ID
Each assembly listed on a PDBe entry page includes a PDBe Complex ID

🆔 Open the complex page from a PDBe Complex ID
Jumps straight to that complex.
Format: ../complexes/{pdbe_complex_id}
Example: ../complexes/PDB-CPX-159519

🔗 Open the complex page from a PDB ID
Auto-resolves to the entry’s preferred assembly.
Format: ../complexes/{pdb_id}
Example: ../complexes/1a00