Patrick Bryant
patrickbryant1.bsky.social
Patrick Bryant
@patrickbryant1.bsky.social
Assistant Professor at Stockholm University.
Dedicated Scientist.
The future of drug design is in AI. RareFoldGPCR: Agonist Design Beyond Natural Amino Acids.
Paper: www.biorxiv.org/content/10.1...
Code: github.com/patrickbryan...
October 3, 2025 at 3:09 PM
Our study where we develop EvoBind2: Design of linear and cyclic peptide binders from protein sequence information is now published! www.nature.com/articles/s42...
July 22, 2025 at 11:23 AM
Now published: our study on human-pathogen protein-protein interactions! We identify 30 interactions with an expected TM-score ≥0.9, tripling the structural coverage in these networks. One novel interaction was validated with mass spectrometry. journals.plos.org/ploscompbiol...
July 6, 2025 at 8:02 AM
Our latest work is out: we designed dual GLP1R/GCGR agonists—cyclic peptides that activate both metabolic receptors, entirely from sequence alone.
This has never been done before. www.biorxiv.org/content/10.1...
June 9, 2025 at 7:00 AM
Happy to release our breakthrough AI-model: RareFold, which predicts and designs proteins with noncanonical AAs. With EvoBindRare, we designed linear & cyclic peptide binders with high affinity & novel binding modes, wet lab validated.

📄 biorxiv.org/content/10.1...
💻 github.com/patrickbryan...
May 25, 2025 at 2:11 PM