Steve Ramirez
okaysteve.bsky.social
Steve Ramirez
@okaysteve.bsky.social
Professor of neuroscience at Boston University
Pinned
Good morning everyone!
So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory*

www.amazon.com/How-Change-M...
How to Change a Memory: One Neuroscientist’s Quest to Alter the Past
Buy How to Change a Memory: One Neuroscientist’s Quest to Alter the Past on Amazon.com ✓ FREE SHIPPING on qualified orders
www.amazon.com
Reposted by Steve Ramirez
So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking
Ventral tegmental area GABA neurons integrate positive and negative valence - Nature Communications
The role of ventral tegmental area GABA neurons in behavior is unclear. Here, authors show that VTA GABA but not dopamine neurons integrate positive and negative valence to encode motivational conflic...
www.nature.com
November 24, 2025 at 4:18 PM
Reposted by Steve Ramirez
"I hope that the wearing-my-humanity-on-my-sleeves part at least continues to normalize the process of 'You’re going to have great days, and you’re going to have atrocious days in life.'"

It does, @okaysteve.bsky.social. It really does.

(via @undark.org)

undark.org/2025/10/29/i...
How Memories Might Be Used to Help Heal the Brain
In a new book, Steve Ramirez explores the potential of memory manipulation to ease depression and other afflictions.
undark.org
November 21, 2025 at 11:55 PM
Reposted by Steve Ramirez
It's time to meet your #OptoGRC2026 chairs!

Co-vice chair @tinakim-neuro.bsky.social is an assistant professor at @princeton.edu who spent the summer building a van for weekend adventures 🚐✨

She's most looking forward to meeting new people & exploring areas outside of her usual wheelhouse!
November 20, 2025 at 7:23 PM
Reposted by Steve Ramirez
Thank you, @thetransmitter.bsky.social, for including me on the list of Rising Stars in Neuroscience along with so many other spectacular neuroscientists! It is an honor to receive this recognition!
November 18, 2025 at 9:19 PM
Reposted by Steve Ramirez
"The idea of activating a memory? Very 'Total Recall' with a bit of 'Inception' thrown in. We felt like kids again, and our playground was the science lab." Read a full excerpt from "How to Change a Memory: One Neuroscientist's Quest to Alter the Past." 📚
Two Neuroscientists Envision A ‘Repair Shop’ For The Brain
In “How to Change a Memory,” neuroscientist Steve Ramirez embarks on a project to find and reactivate memories in the brains of mice.
buff.ly
November 19, 2025 at 1:24 AM
Reposted by Steve Ramirez
Meditations on memory | Science www.science.org/doi/10.1126/...
It was an honour to review @okaysteve.bsky.social ’s How to Change a Memory for Science. The book speaks for itself, bold, inspiring, and full of soul. I’m just proud to highlight the incredible work behind it. So proud of you, Steve
Meditations on memory
A neuroscientist presents an intimate portrait of engram research
www.science.org
November 17, 2025 at 7:44 PM
Reposted by Steve Ramirez
At the pre #SfN @storiesofwin.bsky.social Symposium. Inspiring, entertaining, motivating, and encouraging to hear all these honest stories from these women scientists who truly are making an impact on their environment and science in general.
November 15, 2025 at 6:56 PM
Reposted by Steve Ramirez
Final version published here in @cellpress.bsky.social: Structure

www.cell.com/structure/fu...
November 15, 2025 at 4:39 PM
Reposted by Steve Ramirez
Check out this book from a neuroscientist studying the creation (and manipulation) of memory, a truly sci-fi level of science! I can only imagine this may be of interest to the type of folks who follow me:

press.princeton.edu/books/hardco...
November 14, 2025 at 6:22 PM
Reposted by Steve Ramirez
In today's podcast, Dr. Steve Ramirez - Boston U (@okaysteve.bsky.social) says memory manipulation in mice is #Inception & #Severance type manipulations. What??? He also shares that memory & imagination light up the same #brain regions.

Catch it all at www.sciencefriday.com/segments/how...
Memories Change. But Can We Change Them On Purpose?
Neuroscientists are manipulating memories in mice in an effort to develop treatments for brain disorders.
www.sciencefriday.com
November 14, 2025 at 6:38 PM
Reposted by Steve Ramirez
check out the @okaysteve.bsky.social lab’s posters (for both neuron and glia enthusiasts) at #SfN2025 on Saturday PM! especially say hello to @siriacoello.bsky.social who is applying to grad school this cycle✨
November 14, 2025 at 7:10 PM
Reposted by Steve Ramirez
Not to brag, but Steve gives a shout out to my 3-year-old son in the intro of this book.

(I lied, this is a brag)

(Also, go buy this book, it is great)
November 14, 2025 at 8:10 PM
Reposted by Steve Ramirez
🚨🚨🚨NEW PAPER ALERT🚨🚨🚨

We present StateSpaceDynamics.jl, an open-source Julia package for fitting probabilistic state-space models (SSMs)—including non-conjugate models like Poisson LDS and switching variants (SLDS). Python has had existing packages that have given this functionality...
Just published in JOSS: 'StateSpaceDynamics.jl: A Julia package for probabilistic state space models (SSMs)' https://doi.org/10.21105/joss.08077
November 14, 2025 at 4:29 PM
Reposted by Steve Ramirez
The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum.

If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...
Sosa Lab - Postdoctoral Researchers
We are seeking postdocs to start in 2026!
www.sosaneurolab.com
November 7, 2025 at 10:53 PM
Reposted by Steve Ramirez
@okaysteve.bsky.social sat down with @franciscorr25.bsky.social to discuss the inspiration behind the book, why he decided to write it partly as a memoir, and what he wants readers to take away from reading it.

#neuroskyence

www.thetransmitter.org/memory/how-t...
November 7, 2025 at 2:13 PM
Reposted by Steve Ramirez
In How to Change a Memory, neuroscientist @okaysteve.bsky.social shares his disarmingly personal account of the new science of memory manipulation.⁠

🎧️📔 The #audiobook, read by the author himself, is out now!

Add it to your #audio library: press.princeton.edu/books/audio/...
November 4, 2025 at 8:46 PM
Reposted by Steve Ramirez
Excited to share the latest from the lab on the molecular mechanisms of silencing and un-silencing a hippocampal engram ensemble. Was fun using a variant of the EPSILON technique developed by Adam Cohen's lab.
(1/2)

www.sciencedirect.com/science/arti...
Molecular mechanisms mediating engram ensemble retrievability state in mice
Engrams, ensembles of neurons that store memories, exist along a continuum of retrievability. Normally, sensory cues can reactivate a latent engram to…
www.sciencedirect.com
October 30, 2025 at 3:32 PM
Reposted by Steve Ramirez
How to Change a Memory by @okaysteve.bsky.social is out now!

Discover a disarmingly personal account of the new science of memory manipulation by one of today’s leading pioneers in the field.

Learn more and order yours: press.princeton.edu/books/hardco...

#Neuroscience #Memory
November 4, 2025 at 5:37 PM
Book launch day is here 🚀

How to Change a Memory, in physical and audio form: www.amazon.com/How-Change-M...

and here's a preview of one of the book's central themes: memories change and, as a result, we change too🧠.

www.statnews.com/2025/11/04/a...
How to Change a Memory: One Neuroscientist’s Quest to Alter the Past
Buy How to Change a Memory: One Neuroscientist’s Quest to Alter the Past on Amazon.com ✓ FREE SHIPPING on qualified orders
www.amazon.com
November 4, 2025 at 2:33 PM
Reposted by Steve Ramirez
Tomorrow (Nov 3) at 6:30pm EST, join @harvardbookstore.bsky.social, the Harvard University Division of Science, and @harvardlibrary.bsky.social in welcoming award-winning neuroscientist @okaysteve.bsky.social for a discussion and signing of his new book, How to Change a Memory

RSVP: buff.ly/PEwnVu8
November 2, 2025 at 5:03 PM
Reposted by Steve Ramirez
@okaysteve.bsky.social chatted with @undark.org about how memories can heal the brain and his new book, How to Change a Memory (publishing 11/4). Check out the interview:
How Memories Might Be Used to Help Heal the Brain
In a new book, Steve Ramirez explores the potential of memory manipulation to ease depression and other afflictions.
undark.org
October 29, 2025 at 4:36 PM
Reposted by Steve Ramirez
In How to Change a Memory, @okaysteve.bsky.social draws on his own memories—of friendship, family, loss, & recovery—to reveal how memory can be turned on & off like a switch, edited, & even constructed from nothing.

Out 4 November. Check out a free preview: press.princeton.edu/books/hardco...
October 27, 2025 at 5:24 PM
Reposted by Steve Ramirez
Next week, Nov 3 at 6:30pm EST, join @harvardbookstore.bsky.social, the Harvard University Division of Science, and @harvardlibrary.bsky.social in welcoming award-winning neuroscientist @okaysteve.bsky.social for a discussion and signing of his new book, How to Change a Memory

RSVP: buff.ly/PEwnVu8
October 27, 2025 at 9:45 PM
Reposted by Steve Ramirez
On November 7th, DON'T MISS @bostonu.bsky.social's Dr. Rebecca Suthard when she JOINS #MSNSeminars. Hosted by Drs. Brian Kipp, Chloe Lopez-Lee and Rimjhim Tomar, Dr. Suthard will present “A hippocampal astrocytic sequence emerges during learning and memory". @mountsinainyc.bsky.social
October 27, 2025 at 1:26 PM