Reposted by Ojas Singh
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling
Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...
www.biorxiv.org
December 11, 2025 at 11:34 AM
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Reposted by Ojas Singh
We just did some maintenance and updates to glycoshape.org,
✅ Fancy background with floating SNFG symbols 🤩
✅ 'Latest Updates' feed from this account on bsky 🤩
✅ Download PDB with SASA values in Re-Glyco Ensemble 🤩
Check it out!
✅ Fancy background with floating SNFG symbols 🤩
✅ 'Latest Updates' feed from this account on bsky 🤩
✅ Download PDB with SASA values in Re-Glyco Ensemble 🤩
Check it out!
December 5, 2025 at 12:23 PM
We just did some maintenance and updates to glycoshape.org,
✅ Fancy background with floating SNFG symbols 🤩
✅ 'Latest Updates' feed from this account on bsky 🤩
✅ Download PDB with SASA values in Re-Glyco Ensemble 🤩
Check it out!
✅ Fancy background with floating SNFG symbols 🤩
✅ 'Latest Updates' feed from this account on bsky 🤩
✅ Download PDB with SASA values in Re-Glyco Ensemble 🤩
Check it out!
Reposted by Ojas Singh
Hello #glycotime! GlycoShape makes its debut on bsky today 🦋🎉 Follow us for news, updates and fun-facts (I take full responsibility for those, Ojas @ojas-singh.bsky.social 😆) below ⬇️
Hello bsky 🦋 GlycoShape is now here to give you updates on our glycan 3D database, toolbox, glyco fun-facts and news!
We just updated server, so clear your browser's cache, and build some glycoproteins with us 🍬
We'll have great new tools coming up soon, so follow us for some exciting #glycotime
We just updated server, so clear your browser's cache, and build some glycoproteins with us 🍬
We'll have great new tools coming up soon, so follow us for some exciting #glycotime
a close up of a feather on a rock with the words `` hello '' written in white letters .
ALT: a close up of a feather on a rock with the words `` hello '' written in white letters .
media.tenor.com
November 24, 2025 at 4:53 PM
Hello #glycotime! GlycoShape makes its debut on bsky today 🦋🎉 Follow us for news, updates and fun-facts (I take full responsibility for those, Ojas @ojas-singh.bsky.social 😆) below ⬇️
Reposted by Ojas Singh
Super excited by our new #glycotime preprint! A long-term project from my group with awesome collaborator @elisafadda.bsky.social
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1...
thread below 👇
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1...
thread below 👇
a cartoon drawing of a pitcher and cup of sugar on a table
ALT: a cartoon drawing of a pitcher and cup of sugar on a table
media.tenor.com
September 9, 2025 at 7:32 AM
Super excited by our new #glycotime preprint! A long-term project from my group with awesome collaborator @elisafadda.bsky.social
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1...
thread below 👇
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1...
thread below 👇
Reposted by Ojas Singh
When glycan recognition is linked to immune response, you need fine tuning! 😎
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
June 22, 2025 at 10:42 AM
When glycan recognition is linked to immune response, you need fine tuning! 😎
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Reposted by Ojas Singh
Registration to our "Structural Glycoscience" Summer School is open !! Come to Grenoble for #glycotime lectures, practicals, visit to @esrf.fr @cermav.bsky.social and IBS. Information and registration at glycoalps.univ-grenoble-alpes.fr/news/summer-...
March 12, 2025 at 9:44 AM
Registration to our "Structural Glycoscience" Summer School is open !! Come to Grenoble for #glycotime lectures, practicals, visit to @esrf.fr @cermav.bsky.social and IBS. Information and registration at glycoalps.univ-grenoble-alpes.fr/news/summer-...
Reposted by Ojas Singh
Glycoshape is 1 year old! 🎂🎁 🎉 Last year today we launched glycoshape.org after extensive consultation with a team of friends and colleagues. As head chef, it is my pleasure and duty to give a few thanks before the toast🥂 1/3
December 13, 2024 at 5:32 PM
Glycoshape is 1 year old! 🎂🎁 🎉 Last year today we launched glycoshape.org after extensive consultation with a team of friends and colleagues. As head chef, it is my pleasure and duty to give a few thanks before the toast🥂 1/3
Reposted by Ojas Singh
Christmas arrived early for me🎄🎁 just got a hard copy of the Nature Methods Nov 2024 issue with our GlycoShape article in it ❤️❤️ it smells sooo nice!!! 🤩🤣
doi.org/10.1038/s415...
doi.org/10.1038/s415...
December 11, 2024 at 5:55 PM
Christmas arrived early for me🎄🎁 just got a hard copy of the Nature Methods Nov 2024 issue with our GlycoShape article in it ❤️❤️ it smells sooo nice!!! 🤩🤣
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Reposted by Ojas Singh
And the best poster award #SfG2024 goes to.....Ojas Singh @ojas-singh.bsky.social for his incredible work on GlycoShape!!!! 🎉🎊🎉🎊🎉🎊 Super congrats Ojas we are suuuper proud of you! #glycotime
November 13, 2024 at 8:31 PM
And the best poster award #SfG2024 goes to.....Ojas Singh @ojas-singh.bsky.social for his incredible work on GlycoShape!!!! 🎉🎊🎉🎊🎉🎊 Super congrats Ojas we are suuuper proud of you! #glycotime