Nico Schramma
@nicoschramma.bsky.social
PostDoc: Jaap van Buul medicalbiochemistry.nl (AMC)
Physics PhD Fluidlab.nl (UniAmsterdam)
Endothelial Cells - Chloroplast motion - Biofluids - Bioluminescence - Active Matter - Living Glasses 🧫
https://scholar.google.com/citations?user=9TZXohoAAAAJ&hl=d
Physics PhD Fluidlab.nl (UniAmsterdam)
Endothelial Cells - Chloroplast motion - Biofluids - Bioluminescence - Active Matter - Living Glasses 🧫
https://scholar.google.com/citations?user=9TZXohoAAAAJ&hl=d
Just won the best poster award for our new work on Chloroplast Packing at the Dutch Biophysics meeting (NWO, BioPM). It was a great collab with Eric Weeks and @mazi1.bsky.social
The Paper is also accepted now, so double good news :)
Stay tuned!!
The Paper is also accepted now, so double good news :)
Stay tuned!!
October 7, 2025 at 5:11 PM
Just won the best poster award for our new work on Chloroplast Packing at the Dutch Biophysics meeting (NWO, BioPM). It was a great collab with Eric Weeks and @mazi1.bsky.social
The Paper is also accepted now, so double good news :)
Stay tuned!!
The Paper is also accepted now, so double good news :)
Stay tuned!!
The Bioluminescent garment is now in Kunsthal Rotterdam in the big Iris van Herpen exhibition
< SCULPTING THE SENSES >
www.kunsthal.nl/nl/plan-je-b...
Extremely happy to have been there at the premiere and opening!
I recommend everyone interested in science or fashion design to visit!!
🩵👗
< SCULPTING THE SENSES >
www.kunsthal.nl/nl/plan-je-b...
Extremely happy to have been there at the premiere and opening!
I recommend everyone interested in science or fashion design to visit!!
🩵👗
September 30, 2025 at 7:02 AM
The Bioluminescent garment is now in Kunsthal Rotterdam in the big Iris van Herpen exhibition
< SCULPTING THE SENSES >
www.kunsthal.nl/nl/plan-je-b...
Extremely happy to have been there at the premiere and opening!
I recommend everyone interested in science or fashion design to visit!!
🩵👗
< SCULPTING THE SENSES >
www.kunsthal.nl/nl/plan-je-b...
Extremely happy to have been there at the premiere and opening!
I recommend everyone interested in science or fashion design to visit!!
🩵👗
Beyond happy!
Yesterday I obtained my 🔥PhD🔥 cum laude🔥(highest award) with my work "On Light and Life - Physics of Chloroplast Motion and Bioluminescence"🌿✨
Thanks to so so so many people involved in the work and that have been a huge support to me during this time - especially @mazi1.bsky.social
Yesterday I obtained my 🔥PhD🔥 cum laude🔥(highest award) with my work "On Light and Life - Physics of Chloroplast Motion and Bioluminescence"🌿✨
Thanks to so so so many people involved in the work and that have been a huge support to me during this time - especially @mazi1.bsky.social
September 18, 2025 at 6:53 AM
Beyond happy!
Yesterday I obtained my 🔥PhD🔥 cum laude🔥(highest award) with my work "On Light and Life - Physics of Chloroplast Motion and Bioluminescence"🌿✨
Thanks to so so so many people involved in the work and that have been a huge support to me during this time - especially @mazi1.bsky.social
Yesterday I obtained my 🔥PhD🔥 cum laude🔥(highest award) with my work "On Light and Life - Physics of Chloroplast Motion and Bioluminescence"🌿✨
Thanks to so so so many people involved in the work and that have been a huge support to me during this time - especially @mazi1.bsky.social
Upcoming Symposium!
Physics of Adaptation and Decision making in Biology!
When: September 16
Where: Amsterdam, The Netherlands
Join us here: www.fluidlab.nl/padm25
Speakers:
Ray Goldstein, Sujit Datta, @thomasshimizu.bsky.social, @mirnakramar.bsky.social, @blarson.bsky.social, me
Physics of Adaptation and Decision making in Biology!
When: September 16
Where: Amsterdam, The Netherlands
Join us here: www.fluidlab.nl/padm25
Speakers:
Ray Goldstein, Sujit Datta, @thomasshimizu.bsky.social, @mirnakramar.bsky.social, @blarson.bsky.social, me
August 22, 2025 at 6:56 AM
Upcoming Symposium!
Physics of Adaptation and Decision making in Biology!
When: September 16
Where: Amsterdam, The Netherlands
Join us here: www.fluidlab.nl/padm25
Speakers:
Ray Goldstein, Sujit Datta, @thomasshimizu.bsky.social, @mirnakramar.bsky.social, @blarson.bsky.social, me
Physics of Adaptation and Decision making in Biology!
When: September 16
Where: Amsterdam, The Netherlands
Join us here: www.fluidlab.nl/padm25
Speakers:
Ray Goldstein, Sujit Datta, @thomasshimizu.bsky.social, @mirnakramar.bsky.social, @blarson.bsky.social, me
It's even more crazy to find some of your research data being displayed in VOGUE magazine!
Which scientist doesn't hope to appear once there?! 😁☺️
www.vogue.com/article/iris...
Which scientist doesn't hope to appear once there?! 😁☺️
www.vogue.com/article/iris...
July 13, 2025 at 9:16 PM
It's even more crazy to find some of your research data being displayed in VOGUE magazine!
Which scientist doesn't hope to appear once there?! 😁☺️
www.vogue.com/article/iris...
Which scientist doesn't hope to appear once there?! 😁☺️
www.vogue.com/article/iris...
It's absolutely crazy how well this bio hybrid material worked. Two years ago I helped modeling the mechanochemical response of the material which embeds single celled algae in a gel matrix developed in the lab of Shengqiang Cai at UCSD and refined by Chris Bellamy.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
July 13, 2025 at 9:16 PM
It's absolutely crazy how well this bio hybrid material worked. Two years ago I helped modeling the mechanochemical response of the material which embeds single celled algae in a gel matrix developed in the lab of Shengqiang Cai at UCSD and refined by Chris Bellamy.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Extremely happy that I was awarded with the Emerging Soft Matter Excellence award yesterday!😊
This is a huge honor for me!
But most importantly I met all the amazing other finalists and learned all about their cutting edge research!
engage.aps.org/dsoft/honors...
Thank you @apsdsoft.bsky.social !
This is a huge honor for me!
But most importantly I met all the amazing other finalists and learned all about their cutting edge research!
engage.aps.org/dsoft/honors...
Thank you @apsdsoft.bsky.social !
March 20, 2025 at 1:43 PM
Extremely happy that I was awarded with the Emerging Soft Matter Excellence award yesterday!😊
This is a huge honor for me!
But most importantly I met all the amazing other finalists and learned all about their cutting edge research!
engage.aps.org/dsoft/honors...
Thank you @apsdsoft.bsky.social !
This is a huge honor for me!
But most importantly I met all the amazing other finalists and learned all about their cutting edge research!
engage.aps.org/dsoft/honors...
Thank you @apsdsoft.bsky.social !
Are you at the #APSGlobalSummit2025?
I'm extremely honored to be finalist for the @apsdsoft.bsky.social Emerging Soft Matter Excellence Award!
Curious? Come by on Tuesday 8-11am at the Session MAR-F65 (my talk: 10:24am) 😊
Also just message me if you wanna have a chat :)
@apsphysics.bsky.social
I'm extremely honored to be finalist for the @apsdsoft.bsky.social Emerging Soft Matter Excellence Award!
Curious? Come by on Tuesday 8-11am at the Session MAR-F65 (my talk: 10:24am) 😊
Also just message me if you wanna have a chat :)
@apsphysics.bsky.social
March 16, 2025 at 3:03 PM
Are you at the #APSGlobalSummit2025?
I'm extremely honored to be finalist for the @apsdsoft.bsky.social Emerging Soft Matter Excellence Award!
Curious? Come by on Tuesday 8-11am at the Session MAR-F65 (my talk: 10:24am) 😊
Also just message me if you wanna have a chat :)
@apsphysics.bsky.social
I'm extremely honored to be finalist for the @apsdsoft.bsky.social Emerging Soft Matter Excellence Award!
Curious? Come by on Tuesday 8-11am at the Session MAR-F65 (my talk: 10:24am) 😊
Also just message me if you wanna have a chat :)
@apsphysics.bsky.social
Yay! I won the @apsphysics.bsky.social DBIO Image contest alongside two others!
My colleague @jaredpopo.bsky.social is another winner showing the beauty of plant trichomes!
My picture shows the chloroplast network of the marine dinoflagellate Pyrocystis Lunula!
engage.aps.org/dbio/resourc...
My colleague @jaredpopo.bsky.social is another winner showing the beauty of plant trichomes!
My picture shows the chloroplast network of the marine dinoflagellate Pyrocystis Lunula!
engage.aps.org/dbio/resourc...
January 4, 2025 at 1:41 PM
Yay! I won the @apsphysics.bsky.social DBIO Image contest alongside two others!
My colleague @jaredpopo.bsky.social is another winner showing the beauty of plant trichomes!
My picture shows the chloroplast network of the marine dinoflagellate Pyrocystis Lunula!
engage.aps.org/dbio/resourc...
My colleague @jaredpopo.bsky.social is another winner showing the beauty of plant trichomes!
My picture shows the chloroplast network of the marine dinoflagellate Pyrocystis Lunula!
engage.aps.org/dbio/resourc...
On a last note:
Our colleagues Chenghai Li and Prof. Shengqiang Cai at UCSD also managed to make a 3d printable bio-hybrid gel containing our algae. And we provided some modeling to their work.
Such mechano-luminescent materials are just super fun to play with! :D
www.science.org/doi/10.1126/...
Our colleagues Chenghai Li and Prof. Shengqiang Cai at UCSD also managed to make a 3d printable bio-hybrid gel containing our algae. And we provided some modeling to their work.
Such mechano-luminescent materials are just super fun to play with! :D
www.science.org/doi/10.1126/...
November 19, 2024 at 9:47 AM
On a last note:
Our colleagues Chenghai Li and Prof. Shengqiang Cai at UCSD also managed to make a 3d printable bio-hybrid gel containing our algae. And we provided some modeling to their work.
Such mechano-luminescent materials are just super fun to play with! :D
www.science.org/doi/10.1126/...
Our colleagues Chenghai Li and Prof. Shengqiang Cai at UCSD also managed to make a 3d printable bio-hybrid gel containing our algae. And we provided some modeling to their work.
Such mechano-luminescent materials are just super fun to play with! :D
www.science.org/doi/10.1126/...
To shine a bit more light on the sensing we asked a simple question: "Where does a light-signal go?"
So we shot locally some lasers on our cells to see what happens. In the periphery they contract rapidly on one side only! But on the other side is a fast transient response (contract and extend).
So we shot locally some lasers on our cells to see what happens. In the periphery they contract rapidly on one side only! But on the other side is a fast transient response (contract and extend).
November 19, 2024 at 9:47 AM
To shine a bit more light on the sensing we asked a simple question: "Where does a light-signal go?"
So we shot locally some lasers on our cells to see what happens. In the periphery they contract rapidly on one side only! But on the other side is a fast transient response (contract and extend).
So we shot locally some lasers on our cells to see what happens. In the periphery they contract rapidly on one side only! But on the other side is a fast transient response (contract and extend).
To make more quantitatively sense out of the data, we segmented the cell and measured nodes and edges of the networks, suggesting the motion of the nodes toward the center, while simultaneously buckling.
Also the topology of the structure remains conserved upon folding and unfolding.
Also the topology of the structure remains conserved upon folding and unfolding.
November 19, 2024 at 9:47 AM
To make more quantitatively sense out of the data, we segmented the cell and measured nodes and edges of the networks, suggesting the motion of the nodes toward the center, while simultaneously buckling.
Also the topology of the structure remains conserved upon folding and unfolding.
Also the topology of the structure remains conserved upon folding and unfolding.
This is similar to auxetic metamaterials: by harnessing structure, one can "contract" an essentially elastic material into all directions.
If you'd squeeze a ball 🥎 it would extend in a perpendicular direction due to conservation of volume.
But a Hoberman sphere for example behaves differently:
If you'd squeeze a ball 🥎 it would extend in a perpendicular direction due to conservation of volume.
But a Hoberman sphere for example behaves differently:
November 19, 2024 at 9:47 AM
This is similar to auxetic metamaterials: by harnessing structure, one can "contract" an essentially elastic material into all directions.
If you'd squeeze a ball 🥎 it would extend in a perpendicular direction due to conservation of volume.
But a Hoberman sphere for example behaves differently:
If you'd squeeze a ball 🥎 it would extend in a perpendicular direction due to conservation of volume.
But a Hoberman sphere for example behaves differently:
The cell contacts its chloroplast area by up to 40%! Where does all the material go?
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
November 19, 2024 at 9:47 AM
The cell contacts its chloroplast area by up to 40%! Where does all the material go?
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
We tried to understand the time scales of the adaptation by using dynamical tests: turning light on and off. This method is similar to what rheologists would do for studying viscoelastic liquids.
We found that the cell essentially works like a low-pass filter. But one question remained unanswered
We found that the cell essentially works like a low-pass filter. But one question remained unanswered
November 19, 2024 at 9:47 AM
We tried to understand the time scales of the adaptation by using dynamical tests: turning light on and off. This method is similar to what rheologists would do for studying viscoelastic liquids.
We found that the cell essentially works like a low-pass filter. But one question remained unanswered
We found that the cell essentially works like a low-pass filter. But one question remained unanswered
At day, it also suffers fluctuations of light.
We screened over ecologically relevant light conditions and found transient, weak and strong responses in form of the contraction of the chloroplast towards the cells center.
This all happens in only a few minutes in a ~100µm sized cell!
We screened over ecologically relevant light conditions and found transient, weak and strong responses in form of the contraction of the chloroplast towards the cells center.
This all happens in only a few minutes in a ~100µm sized cell!
November 19, 2024 at 9:47 AM
At day, it also suffers fluctuations of light.
We screened over ecologically relevant light conditions and found transient, weak and strong responses in form of the contraction of the chloroplast towards the cells center.
This all happens in only a few minutes in a ~100µm sized cell!
We screened over ecologically relevant light conditions and found transient, weak and strong responses in form of the contraction of the chloroplast towards the cells center.
This all happens in only a few minutes in a ~100µm sized cell!
To study that, we looked at our favorite marine dinoflagellate: Pyrocystis lunula 🌙, a bioluminescent algae that emits light upon mechanical stimulation during night, which we also previously studied with mechanical compression tests using micropipettes :D
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...
November 19, 2024 at 9:47 AM
To study that, we looked at our favorite marine dinoflagellate: Pyrocystis lunula 🌙, a bioluminescent algae that emits light upon mechanical stimulation during night, which we also previously studied with mechanical compression tests using micropipettes :D
journals.aps.org/prl/abstract...
journals.aps.org/prl/abstract...
The clue is: in dim light chloroplasts spread all over the cell, increasing light uptake (left), while under strong light, they try to rearrange in such a way that light is passed through the cell (right).
But what about algae? Many algae can't swim-how do they cope with excess light? 🤔
But what about algae? Many algae can't swim-how do they cope with excess light? 🤔
November 19, 2024 at 9:47 AM
The clue is: in dim light chloroplasts spread all over the cell, increasing light uptake (left), while under strong light, they try to rearrange in such a way that light is passed through the cell (right).
But what about algae? Many algae can't swim-how do they cope with excess light? 🤔
But what about algae? Many algae can't swim-how do they cope with excess light? 🤔
💥Beyond happy 💥 Our work is now published in PNAS!
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
November 19, 2024 at 9:47 AM
💥Beyond happy 💥 Our work is now published in PNAS!
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
Hi #SciSky :)
So cool that many are moving here now!
I study how chloroplasts in plants and algae move from a physics-y point of view:
Here's recent work on a dinoflagellate.
doi.org/10.1101/2024...
I'm interested in dynamical systems, complex fluids, bioluminescence, stochastic processes etc. :)
So cool that many are moving here now!
I study how chloroplasts in plants and algae move from a physics-y point of view:
Here's recent work on a dinoflagellate.
doi.org/10.1101/2024...
I'm interested in dynamical systems, complex fluids, bioluminescence, stochastic processes etc. :)
November 11, 2024 at 6:29 PM
Hi #SciSky :)
So cool that many are moving here now!
I study how chloroplasts in plants and algae move from a physics-y point of view:
Here's recent work on a dinoflagellate.
doi.org/10.1101/2024...
I'm interested in dynamical systems, complex fluids, bioluminescence, stochastic processes etc. :)
So cool that many are moving here now!
I study how chloroplasts in plants and algae move from a physics-y point of view:
Here's recent work on a dinoflagellate.
doi.org/10.1101/2024...
I'm interested in dynamical systems, complex fluids, bioluminescence, stochastic processes etc. :)
Beginning of 2023 I published the first article from my PhD: We studied how chloroplasts in Elodea densa adapt to changing light conditions. In dim light they are in a collective 'glassy' state which fluidizes in strong light for efficient avoidance motion. Read more: doi.org/10.1073/pnas...
January 6, 2024 at 11:15 AM
Beginning of 2023 I published the first article from my PhD: We studied how chloroplasts in Elodea densa adapt to changing light conditions. In dim light they are in a collective 'glassy' state which fluidizes in strong light for efficient avoidance motion. Read more: doi.org/10.1073/pnas...