Nichollas Scott
@nickescott.bsky.social
Science, glycobiology, mass spectrometry, coffee. Assoc. professor @unimelb. Former ARC future fellow. he/his
Reposted by Nichollas Scott
Postdoc position open!
Digital Pathology: Therapy-response prediction using spatial biology
University of Salzburg
Deadline: October 26th, 2025
We look forward to hearing from you!
www.plus.ac.at/biowissensch...
Digital Pathology: Therapy-response prediction using spatial biology
University of Salzburg
Deadline: October 26th, 2025
We look forward to hearing from you!
www.plus.ac.at/biowissensch...
September 19, 2025 at 9:21 AM
Postdoc position open!
Digital Pathology: Therapy-response prediction using spatial biology
University of Salzburg
Deadline: October 26th, 2025
We look forward to hearing from you!
www.plus.ac.at/biowissensch...
Digital Pathology: Therapy-response prediction using spatial biology
University of Salzburg
Deadline: October 26th, 2025
We look forward to hearing from you!
www.plus.ac.at/biowissensch...
Reposted by Nichollas Scott
Conventional proteomics searches struggle with many modifications and fully open searches may be difficult to interpret. We introduce a "detailed" mass offset search in #MSFragger boosting interpretability and localization especially in complex cases (e.g. FPOP data): www.biorxiv.org/content/10.1...
August 1, 2025 at 9:33 PM
Conventional proteomics searches struggle with many modifications and fully open searches may be difficult to interpret. We introduce a "detailed" mass offset search in #MSFragger boosting interpretability and localization especially in complex cases (e.g. FPOP data): www.biorxiv.org/content/10.1...
Reposted by Nichollas Scott
RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot.
nationalmaglab.org/careers/meet...
nationalmaglab.org/careers/meet...
Alan Marshall: A scientist and a Gentleman - MagLab
Meet one of the greatest innovators in the history of mass spectrometry, hard at work.
nationalmaglab.org
June 12, 2025 at 2:03 PM
RIP Alan Marshall, one of the greatest mass spectrometrists ever, and a great human to boot.
nationalmaglab.org/careers/meet...
nationalmaglab.org/careers/meet...
Really nice to see this work finally out in print. This has been a long term project (> 3 years) in the lab to understand why we couldn't make a few mutants in the burkholderia o-linked glycan biosynthesis pathway. Special shout out to Leila who drove most of this work! www.jbc.org/article/S002...
The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential
Periplasmic O-linked protein glycosylation is a highly conserved process observed
across the Burkholderia genus. Within Burkholderia, protein glycosylation requires
the five-gene cluster known as the ...
www.jbc.org
May 23, 2025 at 5:52 PM
Really nice to see this work finally out in print. This has been a long term project (> 3 years) in the lab to understand why we couldn't make a few mutants in the burkholderia o-linked glycan biosynthesis pathway. Special shout out to Leila who drove most of this work! www.jbc.org/article/S002...
Reposted by Nichollas Scott
📣 Calling all students! 📣
Did you know that ANZSMS have travel support for attending ANZSMS conferences and international mass spectrometry conferences? 😮
The deadline for students attending the 30th ANZSMS at AUS-oMicS this year is coming up next week, 18th March! 🚨
Did you know that ANZSMS have travel support for attending ANZSMS conferences and international mass spectrometry conferences? 😮
The deadline for students attending the 30th ANZSMS at AUS-oMicS this year is coming up next week, 18th March! 🚨
March 10, 2025 at 10:54 PM
📣 Calling all students! 📣
Did you know that ANZSMS have travel support for attending ANZSMS conferences and international mass spectrometry conferences? 😮
The deadline for students attending the 30th ANZSMS at AUS-oMicS this year is coming up next week, 18th March! 🚨
Did you know that ANZSMS have travel support for attending ANZSMS conferences and international mass spectrometry conferences? 😮
The deadline for students attending the 30th ANZSMS at AUS-oMicS this year is coming up next week, 18th March! 🚨
Reposted by Nichollas Scott
🎉Announcing our ANZSMS 2025 Medalists 🎉
Congratulations to Prof Nicki Packer from Macquarie University and A/Prof Shane Ellis from University of Wollongong!
Join us at AUS-omics from May 18 - 21 to celebrate this wonderful achievement! 🏆
Read about our medalists here 👉 mailchi.mp/6c90f3d41712...
Congratulations to Prof Nicki Packer from Macquarie University and A/Prof Shane Ellis from University of Wollongong!
Join us at AUS-omics from May 18 - 21 to celebrate this wonderful achievement! 🏆
Read about our medalists here 👉 mailchi.mp/6c90f3d41712...
February 24, 2025 at 11:23 PM
🎉Announcing our ANZSMS 2025 Medalists 🎉
Congratulations to Prof Nicki Packer from Macquarie University and A/Prof Shane Ellis from University of Wollongong!
Join us at AUS-omics from May 18 - 21 to celebrate this wonderful achievement! 🏆
Read about our medalists here 👉 mailchi.mp/6c90f3d41712...
Congratulations to Prof Nicki Packer from Macquarie University and A/Prof Shane Ellis from University of Wollongong!
Join us at AUS-omics from May 18 - 21 to celebrate this wonderful achievement! 🏆
Read about our medalists here 👉 mailchi.mp/6c90f3d41712...
Reposted by Nichollas Scott
Popularity of current DIA data analysis tools (vendor-independent, based on citations of initial publication) Updated for 2024:
February 14, 2025 at 10:24 AM
Popularity of current DIA data analysis tools (vendor-independent, based on citations of initial publication) Updated for 2024:
Reposted by Nichollas Scott
Applications are open for the #FeMS+ 2025 Q2 Empowerment Awards! Thanks @brukercorporation.bsky.social for sponsoring!
Apply here: airtable.com/appyGufCIumj...
#TeamMAssSpec #WomenEmpowerment
Apply here: airtable.com/appyGufCIumj...
#TeamMAssSpec #WomenEmpowerment
February 10, 2025 at 5:11 PM
Applications are open for the #FeMS+ 2025 Q2 Empowerment Awards! Thanks @brukercorporation.bsky.social for sponsoring!
Apply here: airtable.com/appyGufCIumj...
#TeamMAssSpec #WomenEmpowerment
Apply here: airtable.com/appyGufCIumj...
#TeamMAssSpec #WomenEmpowerment
Reposted by Nichollas Scott
Regardless of current events, highlighting trainees as they continue to excel is a joy.
We just added @emmajays.bsky.social's recent [email protected] publication about chemical deamidation from common proteomics buffer to our website, too.
Congrats Emmajay! #TeamMassSpec
pubs.acs.org/doi/full/10....
We just added @emmajays.bsky.social's recent [email protected] publication about chemical deamidation from common proteomics buffer to our website, too.
Congrats Emmajay! #TeamMassSpec
pubs.acs.org/doi/full/10....
February 10, 2025 at 8:38 PM
Regardless of current events, highlighting trainees as they continue to excel is a joy.
We just added @emmajays.bsky.social's recent [email protected] publication about chemical deamidation from common proteomics buffer to our website, too.
Congrats Emmajay! #TeamMassSpec
pubs.acs.org/doi/full/10....
We just added @emmajays.bsky.social's recent [email protected] publication about chemical deamidation from common proteomics buffer to our website, too.
Congrats Emmajay! #TeamMassSpec
pubs.acs.org/doi/full/10....
I rarely post personal things on here but it's my birthday and as it's the big 4-0 I've spent the week cycling in south east Asia which has been awesome.. 100% recommend cycling around Siem Reap in Cambodia
January 26, 2025 at 9:08 AM
I rarely post personal things on here but it's my birthday and as it's the big 4-0 I've spent the week cycling in south east Asia which has been awesome.. 100% recommend cycling around Siem Reap in Cambodia
Reposted by Nichollas Scott
⏰ Time’s ticking! Only 2 weeks left to submit your oral presentation abstract for #AUSoMicS 2025!
🗓️ Deadline: Jan 31st, 2025
Submit your abstract here: ausomics.com/abstracts
#metabolomics #proteomics #glycomics #massspectrometry #multiomics
@anzsms.bsky.social @ozglyco.bsky.social
🗓️ Deadline: Jan 31st, 2025
Submit your abstract here: ausomics.com/abstracts
#metabolomics #proteomics #glycomics #massspectrometry #multiomics
@anzsms.bsky.social @ozglyco.bsky.social
January 21, 2025 at 8:07 AM
⏰ Time’s ticking! Only 2 weeks left to submit your oral presentation abstract for #AUSoMicS 2025!
🗓️ Deadline: Jan 31st, 2025
Submit your abstract here: ausomics.com/abstracts
#metabolomics #proteomics #glycomics #massspectrometry #multiomics
@anzsms.bsky.social @ozglyco.bsky.social
🗓️ Deadline: Jan 31st, 2025
Submit your abstract here: ausomics.com/abstracts
#metabolomics #proteomics #glycomics #massspectrometry #multiomics
@anzsms.bsky.social @ozglyco.bsky.social
Reposted by Nichollas Scott
Our latest work on Siglec binding to sulfated glycans. Great help: @khookh.bsky.social, @pengwu.bsky.social ,@raflynn5.bsky.social. Fom 1st PhD graduate of the lab (Jaesoo Jung) and help from Edward, Zeinab, Jhon, Kelli, @tayloregray.bsky.social, and Chris from my lab.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Understanding the Glycosylation Pathways Involved in the Biosynthesis of the Sulfated Glycan Ligands for Siglecs
Carbohydrate sulfation plays a pivotal role in modulating the strength of Siglec–glycan interactions. Recently, new aspects of Siglec binding to sulfated cell surface carbohydrates have been discovere...
pubs.acs.org
January 22, 2025 at 2:32 AM
Our latest work on Siglec binding to sulfated glycans. Great help: @khookh.bsky.social, @pengwu.bsky.social ,@raflynn5.bsky.social. Fom 1st PhD graduate of the lab (Jaesoo Jung) and help from Edward, Zeinab, Jhon, Kelli, @tayloregray.bsky.social, and Chris from my lab.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Nichollas Scott
Polysialylation is a general feature of immune activation https://www.biorxiv.org/content/10.1101/2025.01.10.632476v1
January 14, 2025 at 9:16 PM
Polysialylation is a general feature of immune activation https://www.biorxiv.org/content/10.1101/2025.01.10.632476v1
Reposted by Nichollas Scott
I’m looking for a postdoc with experience in #glycosyltransferases and/or yeast/insect #proteinexpression
A new EU pathfinder project begins on 1st February 2025.
Contact me if interested!
A new EU pathfinder project begins on 1st February 2025.
Contact me if interested!
December 26, 2024 at 7:50 PM
I’m looking for a postdoc with experience in #glycosyltransferases and/or yeast/insect #proteinexpression
A new EU pathfinder project begins on 1st February 2025.
Contact me if interested!
A new EU pathfinder project begins on 1st February 2025.
Contact me if interested!
Oh man this hits way too close to me🤣
Coworker: “Wow looks like you’re queuing up a lot of LC-MS runs over the holiday break.”
Me:
Me:
December 22, 2024 at 2:33 AM
Oh man this hits way too close to me🤣
Reposted by Nichollas Scott
Excited to share this story describing new tools for studying Salmonella virulence. We engineered six multimutant strains to be deficient for different sets of SPI-2 T3SS effectors. We think there's lots of potential for new discoveries using these strains www.biorxiv.org/content/10.1...
Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization
Salmonella enterica spp. rely on translocation of effector proteins through the SPI-2 encoded type III secretion system (T3SS) to achieve pathogenesis. More than 30 effectors contribute to manipulatio...
www.biorxiv.org
December 15, 2024 at 3:48 PM
Excited to share this story describing new tools for studying Salmonella virulence. We engineered six multimutant strains to be deficient for different sets of SPI-2 T3SS effectors. We think there's lots of potential for new discoveries using these strains www.biorxiv.org/content/10.1...
An early Xmas present of a portrait of my puppy for my work office :)
December 7, 2024 at 9:56 PM
An early Xmas present of a portrait of my puppy for my work office :)
Reposted by Nichollas Scott
For my first Bluesky post … let me introduce you to Paracoxiella! This has been a fun adventure - shedding light on a mysterious Dot/Icm Coxiellaceae causing trouble for crayfish. A wonderful collaboration across rivers, states and oceans! www.biorxiv.org/content/10.1...
The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family
The Coxiellaceae bacterial family, within the order Legionellales, is defined by a collection of poorly characterized obligate intracellular bacteria. The zoonotic pathogen and causative agent of huma...
www.biorxiv.org
December 3, 2024 at 9:49 PM
For my first Bluesky post … let me introduce you to Paracoxiella! This has been a fun adventure - shedding light on a mysterious Dot/Icm Coxiellaceae causing trouble for crayfish. A wonderful collaboration across rivers, states and oceans! www.biorxiv.org/content/10.1...
You could say this is cray-zie cool work, super fun work from @hayleyjnewton.bsky.social and co!
The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family https://www.biorxiv.org/content/10.1101/2024.12.02.626477v1
The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family https://www.biorxiv.org/content/10.1101/2024.12.02.626477v1
The Coxiellaceae bacterial family, within the order Legionellales, is defined by a collection of poo
www.biorxiv.org
December 3, 2024 at 9:46 AM
You could say this is cray-zie cool work, super fun work from @hayleyjnewton.bsky.social and co!
Reposted by Nichollas Scott
I'm recruiting! I'm looking for a motivated postdoctoral scientist to join my new team at SCELSE in Singapore. The role will explore various aspects of how #eDNA is produced and utilised in #Pseudomonas aeruginosa biofilms.
#Microsky #phagesky #Science
ntu.wd3.myworkdayjobs.com/Careers/job/...
#Microsky #phagesky #Science
ntu.wd3.myworkdayjobs.com/Careers/job/...
Research Fellow (eDNA in Biofilms)
The Singapore Centre for Environmental Life Sciences Engineering (SCELSE) is a unique interdisciplinary Research Centre of Excellence (RCE), funded by National Research Foundation, Ministry of Educati...
ntu.wd3.myworkdayjobs.com
December 2, 2024 at 6:49 AM
I'm recruiting! I'm looking for a motivated postdoctoral scientist to join my new team at SCELSE in Singapore. The role will explore various aspects of how #eDNA is produced and utilised in #Pseudomonas aeruginosa biofilms.
#Microsky #phagesky #Science
ntu.wd3.myworkdayjobs.com/Careers/job/...
#Microsky #phagesky #Science
ntu.wd3.myworkdayjobs.com/Careers/job/...
Reposted by Nichollas Scott
Registrations are open for AUS-oMicS, a joint meeting of Australasian Proteomics Society, @ozglyco.bsky.social, Australian & NZ Metabolomics Society and @anzsms.bsky.social . Registrations & abstract submissions are now open! #TeamMassSpec #massspectrometry www.ausomics.com
November 28, 2024 at 9:11 AM
Registrations are open for AUS-oMicS, a joint meeting of Australasian Proteomics Society, @ozglyco.bsky.social, Australian & NZ Metabolomics Society and @anzsms.bsky.social . Registrations & abstract submissions are now open! #TeamMassSpec #massspectrometry www.ausomics.com
for my first bluesky post I'm happy to share a fun project from the lab we have been working on for a few years exploring the essentiality of genes involved in o-linked protein glycan biosynthesis in Burkholderia! www.biorxiv.org/content/10.1...
The Late-Stage Steps of Burkholderia cenocepacia Protein O-Linked Glycan Biosynthesis Are Conditionally Essential.
Periplasmic O-linked protein glycosylation is a highly conserved process observed across the Burkholderia genus. Within Burkholderia , protein glycosylation requires the five gene cluster known as the...
www.biorxiv.org
November 23, 2024 at 7:37 AM
for my first bluesky post I'm happy to share a fun project from the lab we have been working on for a few years exploring the essentiality of genes involved in o-linked protein glycan biosynthesis in Burkholderia! www.biorxiv.org/content/10.1...
Reposted by Nichollas Scott
Happy to share our last publication. Diclofenac and colistin synergistically act against colistin-resistant A baumannii in mice at low concentration. They repress expression of type IV pili, causing an antivirulence effect! journals.plos.org/plospathogen...
Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin
Author summary Acinetobacter baumannii causes infections that are difficult to treat due to high rates of antibiotic resistance, leading the World Health Organization and CDC to classify this pathogen...
journals.plos.org
November 22, 2024 at 4:53 AM
Happy to share our last publication. Diclofenac and colistin synergistically act against colistin-resistant A baumannii in mice at low concentration. They repress expression of type IV pili, causing an antivirulence effect! journals.plos.org/plospathogen...
Reposted by Nichollas Scott
