Nick Chiappini 🏳️🌈🧪
@ndchiappini.bsky.social
Lover of weird rxns, reactive intermediates, hockey (mostly 🐧and🐙)and equitable sci. Asst Prof at UNCW. Queer AF. Ligand appreciator. Bird and space nerd. ChemSky. He/him
If they're going to use AI, which they are, it's super important to me they know the WHY and how to write without it bc my god, we are deskilling our students if we don't build a foundation before using the magic box.
November 22, 2025 at 6:30 PM
If they're going to use AI, which they are, it's super important to me they know the WHY and how to write without it bc my god, we are deskilling our students if we don't build a foundation before using the magic box.
Of course! Happy my hoarding has its uses!
November 21, 2025 at 2:02 PM
Of course! Happy my hoarding has its uses!
If it won't be a pain to remove from your system, anthracene can also help as a non-Hg substitute
November 21, 2025 at 1:57 PM
If it won't be a pain to remove from your system, anthracene can also help as a non-Hg substitute
For improved efficiency/tolerance of more fragile func, a catalytic (~1%) amt of HgCl2 or PbCl2 can give it a lighter touch
November 21, 2025 at 1:56 PM
For improved efficiency/tolerance of more fragile func, a catalytic (~1%) amt of HgCl2 or PbCl2 can give it a lighter touch
This is so friggin cool. Thank you for the reminder that I have to pre-order!! Doing so now 😎
November 21, 2025 at 1:41 PM
This is so friggin cool. Thank you for the reminder that I have to pre-order!! Doing so now 😎
Raney Ni (W2) can also do the job, but isn't as efficient in terms of amount needed per sulfur spliced out in my experience
November 21, 2025 at 1:40 PM
Raney Ni (W2) can also do the job, but isn't as efficient in terms of amount needed per sulfur spliced out in my experience
Steve, is it next to an ester? If so, Mg/MeOH can do the job.
I've also used nickel boride for this (just made in situ from NiCl2 and NaBH4 in MeOH)
I've also used nickel boride for this (just made in situ from NiCl2 and NaBH4 in MeOH)
November 21, 2025 at 1:39 PM
Steve, is it next to an ester? If so, Mg/MeOH can do the job.
I've also used nickel boride for this (just made in situ from NiCl2 and NaBH4 in MeOH)
I've also used nickel boride for this (just made in situ from NiCl2 and NaBH4 in MeOH)
Very often. From my colleagues who have been here longer, there seems to be a steep decline in reading comp (and essential arithmetic!) over past 5-6 years that persists past introductory :(
November 19, 2025 at 9:00 PM
Very often. From my colleagues who have been here longer, there seems to be a steep decline in reading comp (and essential arithmetic!) over past 5-6 years that persists past introductory :(
Outstanding line from this piece from Dov Greenbaum in Science Magazine. Highly encourage the read!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Frankenstein and the problem of abandonment
A new adaptation of the cautionary tale is an opportunity to reflect on scientific stewardship
www.science.org
November 10, 2025 at 11:34 PM
Outstanding line from this piece from Dov Greenbaum in Science Magazine. Highly encourage the read!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...