Natalia Zajac
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nataliazajac.bsky.social
Natalia Zajac
@nataliazajac.bsky.social
31 followers 42 following 3 posts
postdoc at the Max Planck Institute for Evolutionary Biology, computational biologist
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Reposted by Natalia Zajac
robinpranter.bsky.social
PhD position on the #evo-devo of lizard color patterns, exploring how pigment cells build diverse patterns using developmental and genomic tools. Links to more info about the project and the researchschool below. Please share with interested students!
December 12, 2025 at 6:52 AM
Reposted by Natalia Zajac
jochenwolflab.bsky.social
Sauna, vodka, tea.

Inhale the North, speciate.

Even ants must pee.

Stankowski (2024) Evol J Linnean Soc

doi.org/10.1093/evol...
Toward the integration of speciation research
Abstract. Speciation research—the scientific field focused on understanding the origin and diversity of species—has a long and complex history. While relev
doi.org
July 26, 2025 at 1:31 PM
Reposted by Natalia Zajac
sinamajidian.bsky.social
APAV: An advanced pangenome analysis and visualization toolkit
journals.plos.org/ploscompbiol...
Fig 1. Overview of APAV pipeline. (A) Workflow for PAV calling and consequent analysis. The coordinates of the target region are first extracted from a GFF file or BED file. The coverage of both the whole region and the element region is calculated based on the BAM files. The PAVs are determined according to their coverage, and interactive reports are generated. Subsequent analyses can be performed using the PAV tables, including genome size estimation, classification and statistical analysis, phenotypic association analysis, and visualization of elements. (B) Interactive analysis reports. The PAV report presents PAV tables, coverage data, pangenome sequences, genome annotation, and sequence alignments. The sample report presents sample tables, phenotype information, and real-time PAV analysis results. https://doi.org/10.1371/journal.pcbi.1013288.g001
July 13, 2025 at 4:22 PM
Reposted by Natalia Zajac
fgcz-en.bsky.social
🧬 New study in Gen. Bio.! We tested how RNA input & PCR cycles affect duplication rates across 4 sequencers. ↘️ RNA = ↗️ duplicates = ↘️ diversity. Key for optimizing RNA-seq protocols! Thanks + congrats to @catharineaquino.bsky.social @nataliazajac.bsky.social + collaborators!

🔗 tinyurl.com/bdcuen59
May 28, 2025 at 2:51 PM
Reposted by Natalia Zajac
sinamajidian.bsky.social
Interesting idea: instead of building the pangenome graph from scratch for new samples, dynamically update it by introducing new nodes/edges from long reads biorxiv.org/content/10.1101/2025.02.07.637057
PALSS-Pangenome Graph Augmentation from Long-reads Specific Strings github.com/ldenti/palss
Fig. 1. Method overview. (i) Pangenome graph is sketched using solid anchors (k-mers) and its distin- guished paths, i.e., haplotypes paths, are indexed using an FMD-index. (ii) Specic strings are computed from long reads and (iii) anchored to the graph using solid anchors. (iv) Based on their anchoring, an- chored specic strings are clustered. (v-vi) Each cluster, composed of several specic strings anchored to (mostly) the same subgraph and which may contain sequencing errors (the red Xs), is assembled and locally realigned back to the corresponding subgraph (in case of a diploid locus, two consensuses are created and analyzed). (vii) The base-level alignments are nally used to augment the initial pangenome graph. https://www.biorxiv.org/content/10.1101/2025.02.07.637057v1.full-text
May 22, 2025 at 2:25 AM
nataliazajac.bsky.social
Last week I had an incredible time at #MemPanG25! I was honoured to have a chance to give a talk! It was great to learn what is new and what is coming in the field of pangenomics. Huge thanks to @thinks.lol , @andreaguarracino.bsky.social, and the whole organizing team for making it happen!
andreaguarracino.bsky.social Andrea Guarracino @andreaguarracino.bsky.social · Feb 24
Want to level up in #pangenomics? Join our workshop, conference & biohackathon in #Memphis, May 11-15, 2025. Connect with leading scientists, embrace genomic diversity, and contribute to cutting-edge software. Register now! pangenome.github.io/MemPanG25/ #Bioinformatics #MemPanG25
May 19, 2025 at 7:14 AM
nataliazajac.bsky.social
Great to see our research on heterogenous and novel transcript expression in single cells of patient-derived clear cell renal cell carcinoma organoids published as part of Long-read sequencing special issue in Genome Research, along fantastic collection of articles on long reads!
genomeresearch.bsky.social Genome Research @genomeresearch.bsky.social · Apr 14
SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.
tinyurl.com/Genome-Res-3...
April 28, 2025 at 7:50 AM
Reposted by Natalia Zajac
mpi-evolbio.bsky.social
We offer 2 PhD Positions in Evolutionary Biology!

1️⃣ Evolutionary Developmental Biology – Craniofacial evolution. (March 31, 2025)

2️⃣ Evolution of Polygenic Traits – Genetic adaptation in Drosophila. (April 30, 2025)

More here: www.evolbio.mpg.de/1639156/Job_...

#PhD #EvoDevo #Genetics
Current job offers
www.evolbio.mpg.de
March 19, 2025 at 7:20 AM