Mark
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mkeller7.bsky.social
Mark
@mkeller7.bsky.social
670 followers 1K following 41 posts
Researcher in bioinformatics working on single-cell data visualization

https://markk.co
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mkeller7.bsky.social
Then you can click the "Open feed on bluesky" button so that you can pin the feed
February 16, 2025 at 6:04 PM
mkeller7.bsky.social
Add a "social graph" rule to include posts from users that you follow, and add sentiment/emotion analysis logic to filter the posts.
February 16, 2025 at 6:04 PM
mkeller7.bsky.social
First go to www.graze.social/app/ and click the + (create a new feed) button
February 16, 2025 at 6:04 PM
mkeller7.bsky.social
See www.science.org/doi/10.1126/scitranslmed.aaq1787
A timeline of basic discoveries leading to FDA approval of imatinib. The discovery by Nowell and Hungerford in 1960 of the chromosomal translocation characteristic of CML, termed the Philadelphia chromosome, led to subsequent identification of the Bcr and Abl genes at the translocation junction. Next followed the demonstration that this translocation led to production of a fusion protein with constitutive Abl kinase activity. These discoveries ultimately informed the development of imatinib, which received FDA approval in 2001. A timeline of basic discoveries leading to FDA approval of the ACE inhibitor captopril. The role of the renin-angiotensin system in regulating blood pressure was discovered in 1898 by Tigerstedt and Bergman, who identified renin activity in kidney extracts. This discovery set the stage for the elucidation of the renin substrate, angiotensinogen (start of dark green shading), eventually leading to the development of captopril and other ACE inhibitors
February 9, 2025 at 10:27 PM
mkeller7.bsky.social
random vis accessibility idea: autoencoder where i/o is a plot & low-dimensional representation is somehow text, constrained to be human-interpretable. Has this been done before? is this just contrastive learning?
Schematic of autoencoder. Input on left reads "image of plot (original)". Output on right reads "image of plot (reconstructed)". Low-dimensional vector diagram in middle is annotated "Text; Constrain/regularize such that text-remains human-interpretable"
December 6, 2024 at 8:16 PM