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Mission Bio
@missionbio.bsky.social
The Tapestri® Platform; the only technology that provides single-cell targeted DNA sequencing at single-base resolution
[Live Webinar] Join our upcoming webinar to see how single-cell proteogenomic analysis of PDX models reveals clonal evolution, resistance mechanisms, and drug interactions under therapeutic pressure.

Secure your spot: watch.getcontrast.io/register/mis...
Single-cell proteogenomic analysis of clonal evolution in PDX models of AML treated with IDH inhibitors
Clonal heterogeneity in acute myeloid leukemia (AML) can drive drug resistance because different clones may respond variably to treatments. Studying the ev...
watch.getcontrast.io
January 29, 2026 at 6:43 PM
Join us at hashtag#FOG2026 Find out how you can directly link genotype to phenotype & unravel the threads of multiomics from the same single-cells.

📍 Visit Booth 117
💡 Seminar Day 1, 2.40 PM, Multiomics Stage
📩 Message us to arrange a meeting

The Mission Bio team look forward to meeting you!
January 15, 2026 at 4:47 PM
[Secure Your Spot] Register today for Single-cell profiling of genome-editing alterations and functional outcomes in CRISPR-engineered cells. Whether you can make it live, or not, register to gain access. watch.getcontrast.io/register/mis...
Single-cell profiling of genome-editing alterations and functional outcomes in CRISPR-engineered cells
To overcome the limitations of bulk analysis in genome editing in applications like therapeutics, which can mask critical off-target events that compromise...
watch.getcontrast.io
December 9, 2025 at 6:34 PM
Attending #ASH2025? Bring any curiosity you might have about the world of Single-cell to booth 2129. You can snag an appt at this link if you prefer to manage your time - go.missionbio.com/ASH2025
December 5, 2025 at 7:15 PM
[Press Release] “The DNA+RNA assay provides powerful resolution into the mutational landscape and cell states within leukemia,” says Bobby Bowman, PhD, Assistant Professor. Read the full release here: missionbio.com/press/target...
Mission Bio Announces Single-Cell Targeted DNA + RNA Assay at ASH 2025, Closing the Mutation-to-Expression Gap in Cancer Research | Mission Bio
Mission Bio launches the Tapestri DNA + RNA Assay, the first single-cell platform to link mutations with gene expression, advancing precision medicine and therapy development.
missionbio.com
November 20, 2025 at 5:58 PM
Discover our webinars right here: watch.getcontrast.io/missionbio
November 11, 2025 at 4:33 PM
[blog post] Adapting Tapestri for Single-Cell RNA-Seq: Customer Stories.

missionbio.com/company/blog...
November 10, 2025 at 10:30 PM
[Upcoming Webinar] See how single-cell DNA + DNA methylation + surface protein profiling with scTAM-seq (on Tapestri) dissects treatment response in MDS/AML using sequential patient bone-marrow samples collected during targeted therapy. watch.getcontrast.io/register/mis...
November 7, 2025 at 10:16 PM
Happy Peppermint Mocha Day to everyone celebrating! Yes, it's true, like the Pumpkin Spice Latte, it pairs wonderfully with our Single-cell Sequencing 101 eBook!

🔗 - missionbio.com/resources/eb...
November 6, 2025 at 11:14 PM
To overcome cellular heterogeneity, the critical challenge driving drug resistance in oncology and impacting safety in cell & gene therapy, targeted single-cell DNA and RNA analysis is the key to linking genetic drivers to their functional expression in every cell.

missionbio.com/company/blog...
Pharma Assay Development with Single-Cell Targeted DNA + RNA Analysis. | Mission Bio
De-risk drug development and cell & gene therapies with targeted single-cell multi-omics linking genomics with gene expression data leveraging Mission Bio’s Pharma Assay Development (PAD) services.
missionbio.com
September 3, 2025 at 8:41 PM
[Open Paper] Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing.

bmccancer.biomedcentral.com/articles/10....
Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing - BMC Cancer
Background Cutaneous squamous cell carcinoma (CSCC) is a prevalent skin cancer with aggressive progression that poses significant challenges, especially in metastatic cases. Single-cell DNA sequencing...
bmccancer.biomedcentral.com
August 25, 2025 at 10:02 PM
In this blog post, discover how single-cell multi-omics helps you see what bulk methods miss. By linking DNA, RNA, and protein in the same cell, researchers can spot relapse earlier, follow clonal evolution, & shape better therapies for cancer and cell & gene therapy. missionbio.com/company/blog...
August 19, 2025 at 4:27 PM
🚨 [New Blog] 🚨 Discover how by combining single-cell targeted DNA and RNA analysis, Mission Bio’s Tapestri platform now lets researchers connect genotype with function for a more complete view of disease biology.

🖊️ - Authored by Jacqueline Marin

Read here: missionbio.com/company/blog...
August 6, 2025 at 3:19 PM
📣 [New Press Release] - Mission Bio is accelerating the development of single-cell tri-omics to unlock deeper insights in cancer research and treatment.

Read the full release here: missionbio.com/press/equity...
August 5, 2025 at 5:33 PM
Last call for savings! 📣

Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data.

Learn more 👉 bit.ly/453RcBr
June 18, 2025 at 4:02 PM
We're excited to announce our newest advancement in precision oncology: the Single-Cell Genotype and Targeted Gene Expression assay! This solution enables simultaneous profiling of genotype and targeted gene expression in over 10,000 cells 🎉

Learn more ➡️ bit.ly/4ktWgUE
June 5, 2025 at 4:33 PM
💸Budget tight? We’ve got your back.

Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data.

Learn more 👉 bit.ly/453RcBr
June 4, 2025 at 4:26 PM
Published today in @nature.com, researchers from @crg.eu and @irbbarcelona.org utilized Tapestri to develop EPI-clone, which tracks clonal dynamics in hematopoiesis with naturally occurring DNA methylation patterns.

Learn more here ➡️ bit.ly/4drZc12
Nature Publication Shows Mission Bio's Tapestri® Platform Enables Real-Time, Single-Cell Tracking of Precancerous Clones Using Natural Epigenetic Markers | Mission Bio
Epigenetic barcoding incorporating Tapestri unlocks high-throughput single-cell lineage tracing of clonality with or without mutation drivers, a previously invisible precursor to cancer development EP...
bit.ly
May 21, 2025 at 3:56 PM
#ASGCT2025 is in full swing! We're having a blast in New Orleans meeting everyone and sharing how Tapestri is advancing genome editing validation with single-cell precision.

Swing by Booth #1749 to say hello to our team! 👋
May 14, 2025 at 6:30 PM
At #ASGCT2025? Don’t miss our poster on advancing genome editing validation with single-cell precision

🧬 Comprehensive On- and Off-target Validation Using Integrated rhAmpSeq and Targeted DNA Resequencing Single-Cell Technology

📅 May 15 | 5:30 PM CT

Learn more here ➡️ bit.ly/4jS33Hc
May 13, 2025 at 3:20 PM
🎉 We're headed to the Big Easy! Join us next week in New Orleans for @asgct.bsky.social #ASGCT2025 🎉

Visit Mission Bio at Booth #1749 to learn more about how Tapestri is advancing #cgt characterization 🧬

Check out the *can't-miss* oral and poster presentations here ➡️ bit.ly/3SrruPD
May 8, 2025 at 4:48 PM
Our partnership with Integrated DNA Technologies is built on the principle of therapeutic safety— bringing single-cell resolution and unmatched precision to genome editing analysis.

Read the full story here 👉 bit.ly/3GBbCro
May 6, 2025 at 3:32 PM
Bulk sequencing and traditional assays miss critical details that impact the safety and efficacy of cell therapies. 🧐

With the Tapestri, you can interrogate zygosity, detect off-target effects, and assess immunophenotype—all in one assay.

Learn more ➡️ bit.ly/42kjBS5
April 17, 2025 at 4:50 PM
Our team is having an *AWSOM* time in Atlanta today at the 4th annual Atlanta Workshop of Single-cell Omics. If you're attending, be sure to swing by our table to say hi! 👋

Learn more about the Tapestri platform here ➡️ missionbio.com/products/pla...
April 16, 2025 at 4:53 PM