Michelle Ward
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michelle-c-ward.bsky.social
Michelle Ward
@michelle-c-ward.bsky.social
Functional genomicist & Assistant Professor at The University of Texas Medical Branch at Galveston. https://www.ward-lab.org/
Our preprint on chromatin accessibility changes in response to DNA-damaging agents in cardiomyocytes is now published. Congrats to Renee et al and two first time co-authors! [1/3]
journals.plos.org/plosgenetics...
Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci
Author summary Anthracyclines are a widely used class of breast cancer drugs that are linked to cardiac toxicity and the development of heart disease in some women. There are hundreds of genetic varia...
journals.plos.org
October 29, 2025 at 5:15 AM
Happy to be at ASHG!
2 students in the lab will present posters on gene regulatory evolution in primates on Thurs:
Emma focuses on responses to stimuli: 9109T
John focuses on transposable elements: 6036T
Please stop by if interested #ASHG25
October 16, 2025 at 3:49 AM
Project led by Sayan investigating the effects of CX-5461, an anti-cancer drug currently in clinical trials, on cardiomyocytes: ‘Topoisomerase II inhibitors CX-5461 and Doxorubicin differ in their cardiotoxicity profiles.’ [1/4] www.biorxiv.org/content/10.1...
July 24, 2025 at 11:52 PM
Happy to share our work led by Renee: ‘Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci.’
www.biorxiv.org/content/10.1...
June 19, 2025 at 12:20 AM
Happy to share the published version of Omar & Sayan’s paper. We generated a DNA-damage-associated cardiomyocyte protein co-expression network to gain insights into tolerance to genetic variation and disease. www.sciencedirect.com/science/arti...
May 9, 2025 at 11:38 PM
Come join us at #ASHG25 in Boston Oct 14-18! Abstract submission site (ashg.org/submit) is now live. Abstracts due June 9th.
May 2, 2025 at 1:02 AM