Cover art for our paper featured on this month's homepage of @commsbio.nature.com!

We see a similar pattern in patient UD. UD had a RIGHT OTC resection, and we observe face representations emerging in LEFT OTC, with voxels in his left OTC also "switching allegiance" from words to faces, an extension of Tina Liu's prior work: www.cell.com/cell-reports...

Notably, we see that over time & pre- to post-surgery, voxels in TC's right OTC "switch allegiance" from representing faces to representing words. That is, word representations emerge in RIGHT OTC after LEFT OTC resection, a complete deviation from the standard topography.

For one patient (TC), we imaged her pre-surgery (at age 13y3m) and twice post-surgery (months and then years after surgery). While we cannot map word representations in superior temporal gyrus (light orange) or inferior frontal gyrus (yellow) PRE-surgery, we can POST-surgery.

With the above in mind, here are a few highlights from our study:

First, we show in several cases of LEFT pediatric OTC resection that word representations are in fact lateralized to the RIGHT hemisphere, both in right OTC and right language cortex (shaded yellow/orange here).

Pediatric patients with unilateral resection develop with only a single OTC. If the topographic emergence of visual stimulus representations is truly malleable, face and word representations may come to emerge in preserved OTC, contralateral to the site of resection.

Joining the app to kickoff being back at #AES!

If you're interested in functional outcomes of epilepsy surgery, stop by poster #2.440 today where I'll be talking about my latest work with Pediatric Epilepsy Surgery Alliance on behavioral & mental health outcomes after pediatric hemispheric surgery.