Michael Giolai
@michaelgiolai.bsky.social
Studying plant immunity, its natural variation and consequences · lainelab.net · omiks.it · scholar.google.com/citations?user=KrJkCqoAAAAJ
Reposted by Michael Giolai
How do bacterial pangenomes evolve, what controls their dynamics, why do they exist?
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle
February 9, 2026 at 10:55 AM
How do bacterial pangenomes evolve, what controls their dynamics, why do they exist?
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle
Reposted by Michael Giolai
EVENT - OPEN Friday Seminar - HOPWOOD LECTURE: Prof. Julia Vorholt, ETH Zurich - "Establishing causality: Opportunities of synthetic communities for plant microbiome research"
🗓️ 13 February 2026
⏰ 11:30 am - 12:30 pm
💻 Register to join online: okt.to/s7xUb5
🗓️ 13 February 2026
⏰ 11:30 am - 12:30 pm
💻 Register to join online: okt.to/s7xUb5
February 6, 2026 at 1:50 PM
EVENT - OPEN Friday Seminar - HOPWOOD LECTURE: Prof. Julia Vorholt, ETH Zurich - "Establishing causality: Opportunities of synthetic communities for plant microbiome research"
🗓️ 13 February 2026
⏰ 11:30 am - 12:30 pm
💻 Register to join online: okt.to/s7xUb5
🗓️ 13 February 2026
⏰ 11:30 am - 12:30 pm
💻 Register to join online: okt.to/s7xUb5
Reposted by Michael Giolai
Open Postdoctoral Researcher position in Biodiversity Economics for a new collaboration between @rececochange.bsky.social and Environmental and resource economics group @helsinki.fi
DL 18 February
jobs.helsinki.fi/job/Helsinki...
DL 18 February
jobs.helsinki.fi/job/Helsinki...
Postdoctoral Researcher in Biodiversity Economics
Postdoctoral Researcher in Biodiversity Economics
jobs.helsinki.fi
February 5, 2026 at 11:08 AM
Open Postdoctoral Researcher position in Biodiversity Economics for a new collaboration between @rececochange.bsky.social and Environmental and resource economics group @helsinki.fi
DL 18 February
jobs.helsinki.fi/job/Helsinki...
DL 18 February
jobs.helsinki.fi/job/Helsinki...
Reposted by Michael Giolai
Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
January 30, 2026 at 1:56 PM
Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...
Reposted by Michael Giolai
This article is now published! academic.oup.com/nargab/artic...
We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.
We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.
January 30, 2026 at 12:41 PM
This article is now published! academic.oup.com/nargab/artic...
We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.
We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.
Reposted by Michael Giolai
Can plant pathogens boost vector fitness?
Together with @hassansalem.bsky.social, we review how phytopathogens can spread further by moonlighting as insect symbionts 🪲 More on this nifty lifestyle in @annualreviews.bsky.social!
www.annualreviews.org/content/jour...
Together with @hassansalem.bsky.social, we review how phytopathogens can spread further by moonlighting as insect symbionts 🪲 More on this nifty lifestyle in @annualreviews.bsky.social!
www.annualreviews.org/content/jour...
Plant Pathogens Moonlighting as Beneficial Insect Symbionts
Herbivorous insects can shape the epidemiology of disease in plants by vectoring numerous phytopathogens. While the consequences of infection are often well-characterized in the host plant, the extent...
www.annualreviews.org
February 2, 2026 at 7:48 AM
Can plant pathogens boost vector fitness?
Together with @hassansalem.bsky.social, we review how phytopathogens can spread further by moonlighting as insect symbionts 🪲 More on this nifty lifestyle in @annualreviews.bsky.social!
www.annualreviews.org/content/jour...
Together with @hassansalem.bsky.social, we review how phytopathogens can spread further by moonlighting as insect symbionts 🪲 More on this nifty lifestyle in @annualreviews.bsky.social!
www.annualreviews.org/content/jour...
Reposted by Michael Giolai
Please share!
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...
January 30, 2026 at 3:04 PM
Please share!
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...
Reposted by Michael Giolai
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
www.science.org
January 30, 2026 at 6:11 AM
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
Reposted by Michael Giolai
Does local adaptation shape community assembly?
Our new study led by @maijajoki.bsky.social available now! We combine viruses, the Åland metapopulation & HMSC modeling to uncover eco-evo drivers of within-host pathogen diversity 🦠
doi.org/10.32942/X2G...
@erc.europa.eu @rececochange.bsky.social
Our new study led by @maijajoki.bsky.social available now! We combine viruses, the Åland metapopulation & HMSC modeling to uncover eco-evo drivers of within-host pathogen diversity 🦠
doi.org/10.32942/X2G...
@erc.europa.eu @rececochange.bsky.social
January 30, 2026 at 6:42 AM
Does local adaptation shape community assembly?
Our new study led by @maijajoki.bsky.social available now! We combine viruses, the Åland metapopulation & HMSC modeling to uncover eco-evo drivers of within-host pathogen diversity 🦠
doi.org/10.32942/X2G...
@erc.europa.eu @rececochange.bsky.social
Our new study led by @maijajoki.bsky.social available now! We combine viruses, the Åland metapopulation & HMSC modeling to uncover eco-evo drivers of within-host pathogen diversity 🦠
doi.org/10.32942/X2G...
@erc.europa.eu @rececochange.bsky.social
Reposted by Michael Giolai
1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577
January 29, 2026 at 11:06 AM
1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577
Reposted by Michael Giolai
Thank you
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org
January 24, 2026 at 3:21 PM
Thank you
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.
Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...
Reposted by Michael Giolai
What can we learn from comparing ~2,000 fungal genomes?
Find out about:
🍄evolutionary transitions
🍄lifestyles
🍄genome dynamics
🍄sampling gaps
🍄efforts to uncover the remaining fungal dark matter
New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev
www.nature.com/articles/s41...
Find out about:
🍄evolutionary transitions
🍄lifestyles
🍄genome dynamics
🍄sampling gaps
🍄efforts to uncover the remaining fungal dark matter
New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev
www.nature.com/articles/s41...
January 20, 2026 at 8:34 PM
What can we learn from comparing ~2,000 fungal genomes?
Find out about:
🍄evolutionary transitions
🍄lifestyles
🍄genome dynamics
🍄sampling gaps
🍄efforts to uncover the remaining fungal dark matter
New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev
www.nature.com/articles/s41...
Find out about:
🍄evolutionary transitions
🍄lifestyles
🍄genome dynamics
🍄sampling gaps
🍄efforts to uncover the remaining fungal dark matter
New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev
www.nature.com/articles/s41...
Reposted by Michael Giolai
New paper led by @hannasusi.bsky.social shows biodiversity responses to carbon farming are highly context-dependent—varying by management, index and taxa 🌱🪱🐞🐦.
Abundance is the most sensitive early indicator for detecting biodiversity impacts!
www.sciencedirect.com/science/arti...
Abundance is the most sensitive early indicator for detecting biodiversity impacts!
www.sciencedirect.com/science/arti...
January 19, 2026 at 8:16 AM
New paper led by @hannasusi.bsky.social shows biodiversity responses to carbon farming are highly context-dependent—varying by management, index and taxa 🌱🪱🐞🐦.
Abundance is the most sensitive early indicator for detecting biodiversity impacts!
www.sciencedirect.com/science/arti...
Abundance is the most sensitive early indicator for detecting biodiversity impacts!
www.sciencedirect.com/science/arti...
Reposted by Michael Giolai
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
January 15, 2026 at 12:32 PM
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
Reposted by Michael Giolai
Reposted by Michael Giolai
Not a single day in 2025 was cooler than the 1991-2020 average, on a global scale. @copernicusecmwf.bsky.social
January 14, 2026 at 9:27 PM
Not a single day in 2025 was cooler than the 1991-2020 average, on a global scale. @copernicusecmwf.bsky.social
Reposted by Michael Giolai
Join us in Norwich this July for the TSL Summer Conference in Plant-Microbe Interactions! ☀️🌱🧬
Discuss the latest approaches & discoveries in plant health with international keynote and local speakers.
APPLY by 30 March '26 ⬇️ Click link for more info
www.tsl.ac.uk/tsl-summer-c...
Discuss the latest approaches & discoveries in plant health with international keynote and local speakers.
APPLY by 30 March '26 ⬇️ Click link for more info
www.tsl.ac.uk/tsl-summer-c...
TSL Summer Conference in Plant-Microbe Interactions, 20th – 31st July…
Inviting Early Career Researchers to join international experts in discussing the latest approaches and discoveries in Plant-Microbe Interactions …
www.tsl.ac.uk
January 14, 2026 at 5:50 PM
Join us in Norwich this July for the TSL Summer Conference in Plant-Microbe Interactions! ☀️🌱🧬
Discuss the latest approaches & discoveries in plant health with international keynote and local speakers.
APPLY by 30 March '26 ⬇️ Click link for more info
www.tsl.ac.uk/tsl-summer-c...
Discuss the latest approaches & discoveries in plant health with international keynote and local speakers.
APPLY by 30 March '26 ⬇️ Click link for more info
www.tsl.ac.uk/tsl-summer-c...
Reposted by Michael Giolai
Here @mikkotiusanen.bsky.social in action collecting this impressive dataset on Calanda
January 15, 2026 at 8:00 AM
Here @mikkotiusanen.bsky.social in action collecting this impressive dataset on Calanda
Reposted by Michael Giolai
Out now 🥳 our study led by @mikkotiusanen.bsky.social!
With data on 1.17 M flowers & 10,000 pollinators 🌼🐝 we show plant–pollinator timing shifts from biotic to abiotic control along alpine gradients ➡️climate change may rewire interaction synchrony
nsojournals.onlinelibrary.wiley.com/doi/10.1002/...
With data on 1.17 M flowers & 10,000 pollinators 🌼🐝 we show plant–pollinator timing shifts from biotic to abiotic control along alpine gradients ➡️climate change may rewire interaction synchrony
nsojournals.onlinelibrary.wiley.com/doi/10.1002/...
nsojournals.onlinelibrary.wiley.com
January 15, 2026 at 7:41 AM
Out now 🥳 our study led by @mikkotiusanen.bsky.social!
With data on 1.17 M flowers & 10,000 pollinators 🌼🐝 we show plant–pollinator timing shifts from biotic to abiotic control along alpine gradients ➡️climate change may rewire interaction synchrony
nsojournals.onlinelibrary.wiley.com/doi/10.1002/...
With data on 1.17 M flowers & 10,000 pollinators 🌼🐝 we show plant–pollinator timing shifts from biotic to abiotic control along alpine gradients ➡️climate change may rewire interaction synchrony
nsojournals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Michael Giolai
We have an open POSTDOC position to explore Marchantia immune receptor biology that is closing on the 18th of Jan. Apply using the link below, and/or email me for more details. www.jic.ac.uk/vacancies/po...
Postdoctoral Researcher (Carella Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Carella Group at the John Innes Centre, working on cutting-edge science in the field of Evo-MPMI (Evolutionary Molecular…
www.jic.ac.uk
January 13, 2026 at 11:31 AM
We have an open POSTDOC position to explore Marchantia immune receptor biology that is closing on the 18th of Jan. Apply using the link below, and/or email me for more details. www.jic.ac.uk/vacancies/po...
Reposted by Michael Giolai
Out after peer review, led by @shanshanwang3.bsky.social.
Gating of immune responses in Arabidopsis mesophyll cells: after initial response, immune gene expression stays hi in some cells, while during PTI other cells reinitiate a growth-related program.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Gating of immune responses in Arabidopsis mesophyll cells: after initial response, immune gene expression stays hi in some cells, while during PTI other cells reinitiate a growth-related program.
nph.onlinelibrary.wiley.com/doi/10.1111/...
January 8, 2026 at 10:59 AM
Out after peer review, led by @shanshanwang3.bsky.social.
Gating of immune responses in Arabidopsis mesophyll cells: after initial response, immune gene expression stays hi in some cells, while during PTI other cells reinitiate a growth-related program.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Gating of immune responses in Arabidopsis mesophyll cells: after initial response, immune gene expression stays hi in some cells, while during PTI other cells reinitiate a growth-related program.
nph.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Michael Giolai
I’m excited to share with you the first @rececochange.bsky.social newsletter, highlighting recent research on biodiversity change, policy-relevant insights and news from across the REC community 💚🌍
Read it here 👉 mailchi.mp/97ed6942f5b8...
Read it here 👉 mailchi.mp/97ed6942f5b8...
REC Newsletter 1/2026
mailchi.mp
January 7, 2026 at 10:54 AM
I’m excited to share with you the first @rececochange.bsky.social newsletter, highlighting recent research on biodiversity change, policy-relevant insights and news from across the REC community 💚🌍
Read it here 👉 mailchi.mp/97ed6942f5b8...
Read it here 👉 mailchi.mp/97ed6942f5b8...
Reposted by Michael Giolai
The Alexander von Humboldt foundation has a call for Climate Protection Fellowships. Information event is tomorrow!
www.humboldt-foundation.de/en/connect/i...
If you are interested in working on a project related to quantitative disease resistance and climatic trade offs, I could possibly be host!
www.humboldt-foundation.de/en/connect/i...
If you are interested in working on a project related to quantitative disease resistance and climatic trade offs, I could possibly be host!
Info event: International Climate Protection Fellowship
If you would like to learn more about the International Climate Protection Fellowship, join our online event by Zoom and get all the information on the programme and the application process first-hand...
www.humboldt-foundation.de
January 6, 2026 at 2:18 PM
The Alexander von Humboldt foundation has a call for Climate Protection Fellowships. Information event is tomorrow!
www.humboldt-foundation.de/en/connect/i...
If you are interested in working on a project related to quantitative disease resistance and climatic trade offs, I could possibly be host!
www.humboldt-foundation.de/en/connect/i...
If you are interested in working on a project related to quantitative disease resistance and climatic trade offs, I could possibly be host!
Reposted by Michael Giolai
Towards a quantitative view of NLR evolution in genome space -- check out where we think the field of #NLR #evolution research is heading in this review led by Luzie Wingen and Aurélien Tellier.
ecoevorxiv.org/repository/v...
#plantscience
ecoevorxiv.org/repository/v...
#plantscience
January 6, 2026 at 9:05 AM
Towards a quantitative view of NLR evolution in genome space -- check out where we think the field of #NLR #evolution research is heading in this review led by Luzie Wingen and Aurélien Tellier.
ecoevorxiv.org/repository/v...
#plantscience
ecoevorxiv.org/repository/v...
#plantscience
Reposted by Michael Giolai
Think you need large volumes for microbial experiments?
Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a...
🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.
Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a...
🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.
From microscale to microbial insights: validating high-throughput microvolume extraction (HiMEx) methods for marine microbial ecology
Abstract. Extracting and directly amplifying DNA from small-volume, low-biomass samples would enable rapid, ultra-high-throughput analyses, facilitating th
academic.oup.com
December 31, 2025 at 8:53 PM
Think you need large volumes for microbial experiments?
Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a...
🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.
Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a...
🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.