Merle Hantsche-Grininger
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merlehantsche.bsky.social
Merle Hantsche-Grininger
@merlehantsche.bsky.social
Visualising chromatin organisation by 3D super-resolution microscopy | Research Scientist in Ellenberg Lab at EMBL Heidelberg
Reposted by Merle Hantsche-Grininger
We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social!
www.biorxiv.org/content/10.1...
#Chromatin #Asgard #Archaea #cryoEM
May 26, 2025 at 4:56 PM
🔬 Interested in chromatin organization? 🔬🧫
The Ellenberg Lab #EMBL is hiring!
⏰ ⏰ ⏰ Application deadline is next week! ⏰ ⏰ ⏰
We are #hiring!

We have two open postdoc/research scientist positions to join our #ERC funded project MITOFOLD to resolve the organization of mitotic chromosomes!

1) experimental biologist shorturl.at/LjGEM
2) data scientist shorturl.at/nDdhQ
Please share! 🙌

We look forward to your application! 🤩
April 15, 2025 at 6:30 PM
Reposted by Merle Hantsche-Grininger
Did you know that DNA must form overlapping loops to give rise to the well-known X-shape of chromosomes? 🧬🧪

New research from EMBL's Ellenberg Group provides new insights into the process of chromosome formation.

@ellenberglab.bsky.social
@andibrunner.bsky.social

www.embl.org/news/science...
How chromosomes shape up for cell division | EMBL
EMBL scientists have shown how overlapping loops of DNA stack upon each other in dividing cells to give rise to rod-shaped chromosomes
www.embl.org
March 24, 2025 at 3:10 PM
Reposted by Merle Hantsche-Grininger
Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

🔗 Preprint here tinyurl.com/3a74uanv
April 11, 2025 at 8:35 AM
Reposted by Merle Hantsche-Grininger
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
April 6, 2025 at 9:45 AM
Are you interested in deciphering chromatin structure using microscopy? 🔬
👇👇The Ellenberg lab is hiring! 👇👇
📣 Please share 📣
We are #hiring!

We have two open postdoc/research scientist positions to join our #ERC funded project MITOFOLD to resolve the organization of mitotic chromosomes!

1) experimental biologist shorturl.at/LjGEM
2) data scientist shorturl.at/nDdhQ
Please share! 🙌

We look forward to your application! 🤩
March 19, 2025 at 3:31 PM
Reposted by Merle Hantsche-Grininger

1 week left - January 31 is deadline for 👇
• Abstract Submission and
• Early Bird Registration
for the 76th Mosbacher Kolloquium with a fantastic lecture program and interesting lunch break events: mosbacher-kolloquium.org/home.html
January 24, 2025 at 7:45 AM
Reposted by Merle Hantsche-Grininger
🚨 Registration is now open! 🚨

Join us for 'Seeing is believing: imaging the molecular processes of life', where cutting-edge imaging methods meet groundbreaking biological discoveries. 🌟#EESImaging

📅 8 – 11 October 2025
📜 Submit your abstract by 2 July!

👉 https://s.embl.org/ees25-09-bl
January 21, 2025 at 1:27 PM
Reposted by Merle Hantsche-Grininger
New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today:
SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion!

www.sciencedirect.com/science/arti...

1/
January 16, 2025 at 4:11 PM
Reposted by Merle Hantsche-Grininger
We are now on Bluesky!

Follow us for exciting #Science around #CellDivision and nuclear organization, illuminated using advanced #imaging #technology - like our last preprint on mitotic chromosome structure and organization: tinyurl.com/yaznnkku
November 25, 2024 at 1:08 PM