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Almost a third of families of children with newly diagnosed acute lymphocytic leukemia had housing or food-related hardships or "catastrophic" income loss during standard chemotherapy, according to a study reported here. #ASH25
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Material Hardship, 'Catastrophic' Income Loss Common in Families of Kids With ALL
Almost a third of families affected by financial toxicity, many with no prior material hardships
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December 10, 2025 at 3:55 PM
A hospital policy to increase the use of perioperative tranexamic acid reduced blood transfusions during major noncardiac surgeries with no apparent impact on clotting events, a cluster randomized trial from Canada found. #ASH25
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Cheap Drug During High-Risk Surgery Reduces Blood Transfusions
Canadian trial backs the routine use of tranexamic acid for major noncardiac procedures
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December 9, 2025 at 10:07 PM
Combining teclistamab (Tecvayli) with subcutaneous daratumumab-hyaluronidase (Darzalex Faspro) significantly improved progression-free survival and overall survival in patients with relapsed/refractory multiple myeloma, the MajesTEC-3 trial showed. #ASH25
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Bispecific Trial in Myeloma Sparks Talks of 'Functional Cure'
Combination reduced risk of progression or death by 83% compared to standard triplet
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December 9, 2025 at 9:33 PM
Challenging medical dogma, the use of IV iron therapy for hospitalized patients with iron deficiency #anemia dealing with acute infections was associated with a reduced risk for death, a retrospective study spanning a quarter-century found. #ASH25
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IV Iron Tied to Lower Mortality Risk in Anemics Battling Infection
Intravenous 'iron is controversial in the setting of infection,' says expert
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December 9, 2025 at 3:07 PM
In a phase III trial with potential practice-changing implications, the non-covalent Bruton's tyrosine kinase inhibitor pirtobrutinib (Jaypirca) induced a higher response rate in chronic lymphocytic leukemia versus covalent ibrutinib (Imbruvica). #ASH25
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Trial Results Could Shuffle Order of BTK Inhibitors for CLL/SLL
Pirtobrutinib topped ibrutinib in patients with untreated or relapsed/refractory disease
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December 9, 2025 at 3:07 PM
For triple-class exposed relapsed or refractory multiple myeloma with EMD, a combination of talquetamab (Talvey) and teclistamab (Tecvayli) achieved high response rates in updated results from the phase II RedirecTT-1 trial. #ASH25 @szusmani.bsky.social
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Dual Targeting of GPRC5D and BCMA Gets High Response Rate in Extramedullary Myeloma
With longer trial follow-up, 79% response seen in disease resistant to therapy
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December 9, 2025 at 3:07 PM
Azacitidine and venetoclax (Venclexta) significantly improved event-free survival in newly diagnosed fit adults with acute myeloid leukemia compared with conventional induction chemotherapy, a phase II randomized trial showed. #ASH25
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Drug Combo Shows Benefits in Fit Patients With Acute Myeloid Leukemia
Primary endpoint more than doubled versus standard induction chemotherapy
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December 9, 2025 at 3:07 PM
Reposted by MedPage Today
Thank you to Barbara Raymond for recommending that I apply to the Public Voices Fellowship on Technology in the Public Interest, my Op Ed Project mentor, Teresa Puente, for her supportive guidance with the process, and to @gfriedman.bsky.socialn for creating a home for my op-ed @ @medpagetoday.com.🫀
Opinion | AI Isn't the Solution for Every Problem
Health organizations should step back and understand what communities want
www.medpagetoday.com
December 9, 2025 at 12:49 PM