Michael Nicholson
@mdnicholson1.bsky.social
Chancellor's Fellow (~Asst. Prof.) University of Edinburgh
| Math modelling for somatic genomics | https://michaeldnicholson.github.io
| Math modelling for somatic genomics | https://michaeldnicholson.github.io
Pinned
Mathematical Modeling Quantifies “Just-Right” APC Inactivation for Colorectal Cancer Initiation
Mathematical modeling of tumor development with different APC genotypes substantiates the “just-right” APC inactivation model and suggests alterations in secondary WNT regulators enhance WNT activity ...
doi.org
Happy to share our recent work quantifying ‘just-right’ APC inactivation in colorectal cancer initiation:
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.
Happy to share our recent work quantifying ‘just-right’ APC inactivation in colorectal cancer initiation:
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.
Mathematical Modeling Quantifies “Just-Right” APC Inactivation for Colorectal Cancer Initiation
Mathematical modeling of tumor development with different APC genotypes substantiates the “just-right” APC inactivation model and suggests alterations in secondary WNT regulators enhance WNT activity ...
doi.org
December 17, 2025 at 3:59 PM
Happy to share our recent work quantifying ‘just-right’ APC inactivation in colorectal cancer initiation:
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.
doi.org/10.1158/0008...
Excellent collaborative teamwork, led by the fantastic Meritxell Brunet Guasch.