Mike Bottery
@mbottery.bsky.social
Microbial Evolution - AMR - University of Manchester
Research Technician: www.jobs.manchester.ac.uk/Job/JobDetai...
Postdoc: www.jobs.manchester.ac.uk/Job/JobDetai...
Postdoc: www.jobs.manchester.ac.uk/Job/JobDetai...
Research Technician in Microbiology:Oxford Road
We are seeking a motivated laboratory-based Research Technician to join a dynamic lab working to understand the evolution of antimicrobial resistance within human fungal pathogens. This role is based in the lab of Dr Bottery, part of the wider Manchester Fungal Infection Group. The role is full-time for 12 months, available from January 2026.
www.jobs.manchester.ac.uk
November 5, 2025 at 3:35 PM
Research Technician: www.jobs.manchester.ac.uk/Job/JobDetai...
Postdoc: www.jobs.manchester.ac.uk/Job/JobDetai...
Postdoc: www.jobs.manchester.ac.uk/Job/JobDetai...
Exciting opportunities to join me in this research will be coming soon! If you're passionate about understanding microbial evolution & tackling antimicrobial resistance, keep an eye out or feel free to get in touch. 🔬🧬 🍄 #AMR #Microbiology #Evolution
July 8, 2025 at 10:06 AM
Exciting opportunities to join me in this research will be coming soon! If you're passionate about understanding microbial evolution & tackling antimicrobial resistance, keep an eye out or feel free to get in touch. 🔬🧬 🍄 #AMR #Microbiology #Evolution
Sounds really exciting Bex!! I kinda miss symbionts, looking forward to hearing about you get up to
December 16, 2024 at 3:58 PM
Sounds really exciting Bex!! I kinda miss symbionts, looking forward to hearing about you get up to
Through the pervasive anthropogenic use of agricultural azoles, a lineage of A. fumigatus has been selected that is multi-azole resistant, multi-fungicide resistant, and also displays increased adaptability, which ultimately will lead to the evolution of a lineage that manifests pan-drug resistance.
December 16, 2024 at 12:04 PM
Through the pervasive anthropogenic use of agricultural azoles, a lineage of A. fumigatus has been selected that is multi-azole resistant, multi-fungicide resistant, and also displays increased adaptability, which ultimately will lead to the evolution of a lineage that manifests pan-drug resistance.
Here, we show that variants in the MMR gene, msh6, are almost uniquely found in strains harbouring azole resistance and result in up to 5-fold increase in mutation rates.
December 16, 2024 at 12:04 PM
Here, we show that variants in the MMR gene, msh6, are almost uniquely found in strains harbouring azole resistance and result in up to 5-fold increase in mutation rates.
Resistance to azoles is spreading most likely due to the use of agricultural fungicides. Resistance can double the risk of mortality from invasive aspergillosis.
December 16, 2024 at 12:04 PM
Resistance to azoles is spreading most likely due to the use of agricultural fungicides. Resistance can double the risk of mortality from invasive aspergillosis.
Only three classes of antifungal drugs available to treat disease, and only one class, the azoles, is suitable for long-term oral administration.
December 16, 2024 at 12:04 PM
Only three classes of antifungal drugs available to treat disease, and only one class, the azoles, is suitable for long-term oral administration.
The mould, found in soil, composts, and decaying vegetation, is potentially deadly to people with a range of health conditions including those with weakened immune systems and respiratory problems.
December 16, 2024 at 12:04 PM
The mould, found in soil, composts, and decaying vegetation, is potentially deadly to people with a range of health conditions including those with weakened immune systems and respiratory problems.