The Matthew
matthewthe.bsky.social
The Matthew
@matthewthe.bsky.social
Bioinformatics group leader ‪@kusterlab.bsky.social‬
Visit my personal website: thematthew.me
Reposted by The Matthew
Our new review paper about Pathway-Centric PTM Data Analysis is out this week in #Proteomics!
We cover databases, enrichment tools, software for pathway reconstruction, and full-fledged platforms that help to interpret high-throughput PTM datasets.
Check it out here: doi.org/10.1002/pmic...
Computational Approaches for Pathway‐Centric Analysis of Protein Post‐Translational Modifications
Protein function is dynamically modulated by post-translational modifications (PTMs). Many different types of PTMs can nowadays be identified and quantified at a large scale using mass spectrometry. ...
doi.org
October 20, 2025 at 7:07 AM
🚀 picked-group-fdr v0.9.0 released!

⬆️ Python 3.10–3.13 support
✅ Support for DIA-NN 2.x results with decoys
⚡ FastLFQ added for MaxLFQ protein quantification

🔍 More: github.com/kusterlab/pi...

#proteomics #openscience #python
GitHub - kusterlab/picked_group_fdr: Scalable, accurate and sensitive protein group FDRs for large-scale mass spectrometry experiments
Scalable, accurate and sensitive protein group FDRs for large-scale mass spectrometry experiments - kusterlab/picked_group_fdr
github.com
May 21, 2025 at 3:34 PM