QQ14: Lykken et al. show that differential phase shifts between grid cell modules may form the basis for the orthogonalization of downstream hippocampal spatial codes during remapping. @clykken.bsky.social

QQ13: We can functionally identify monosynaptic input cells to the CA3 and DG subfields of the hippocampus by combining transgenic mouse lines, a modified rabies virus, and in vivo imaging with a head-mounted 2-photon miniscope. @rijacobsen.bsky.social

QQ12: Obenhaus et al. are presenting results on functionally mapping isochronic populations (cells born around the same time during embryonic development) and show how birth date shapes functional properties of cells in MEC! octoscience.bsky.social

QQ11: RSC is using the HPC spatial code for good! We observed retrosplenial populations encode task structure when behaviourally relevant cues were present in a hippocampal-dependent spatial task.

QQ10: We see minute-scale population drift, not only in LEC, but also MEC and CA1 in conditions with minimal external stimuli, i.e., when mice are head-fixed on a wheel in darkness! @anelautrup.bsky.social

Poster QQ9: Theta sweeps can track moving bait and go backwards!
In our poster, we describe situations in which the stereotypic left-right alternating theta sweep pattern is modulated to cover behaviorally relevant space @azvollan.bsky.social

QQ8: What drives the left–right alternation of theta sweeps? Whether a central-pattern generator (CPG)-like circuit is involved? @rajatsxn.bsky.social

QQ7: How do MEC ultraslow dynamics vary across behavioral states. In free foraging, population dynamics organize in ultraslow sequences while in NREM sleep they present as synchronous oscillations.

QQ6: By combining large high-NA objective, wide-angle MEMS scanning, SiPM detection, and multi-beam multiplexing, this new 2P miniscope (Mini10K) enables cellular-resolution imaging of thousands of neurons in freely moving mice, surpassing current FOV and throughput limits.

QQ5: What is the developmental timeline of the low-dimensional manifolds of the entorhinal cortex? Rings and tori organize at P9-P10 before major sensory-motor milestones, coinciding with other major shifts in MEC cortical dynamics. @me

QQ4: QQ4: We study population dynamics across the spatial navigation circuit as a rat moves between 4 rooms. With 4 NPX probes in CA, MEC/PaS, SUB, and dPreSUB, we see how maps switch at a fine timescale and track when each region settles into the correct representation. @jocarpenter.bsky.social

QQ3: We observe hexagonal grid cells even in environments with elevation changes! The hexagonal pattern is cleaner on the surface of a ramp and on a dome seen from above, and more distorted on a cone seen from above.

QQ2: Where are the grid cells and if so, how many? We find that grid cells form a discrete "hot spot" segregated from other functional cell types in the superficial layers of MEC and PaS. @martipof.bsky.social