Masschelein Lab
@masscheleinlab.bsky.social
Engineering Microbes for Drug Discovery & Lead Optimization | Exploring the Biosynthetic Creativity of Microorganisms
@VIB @KU Leuven -- www.masscheleinlab.org
@VIB @KU Leuven -- www.masscheleinlab.org
Reposted by Masschelein Lab
Oral abstract submission is now open for Directing Biosynthesis VIII, an event that has been connecting #Biosynthesis researchers for over a decade.
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
November 17, 2025 at 3:51 PM
Oral abstract submission is now open for Directing Biosynthesis VIII, an event that has been connecting #Biosynthesis researchers for over a decade.
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Polyunsaturated fatty acid (PUFA) synthase enzymes turn out to be far more versatile than we ever imagined! In our new preprint, we reveal a largely untapped biosynthetic space where they team up with PKSs and NRPSs to create new types of bioactive amphiphilic metabolites.
👉http://bit.ly/4hzUUak
👉http://bit.ly/4hzUUak
Charting the biosynthetic landscape of hybrid polyketide-nonribosomal peptide-specialized lipids
Polyunsaturated fatty acid (PUFA) synthase-like enzymes are best known for their role in membrane lipid biosynthesis in marine bacteria, but have also been repurposed for the assembly of specialized l...
bit.ly
October 27, 2025 at 9:56 AM
Polyunsaturated fatty acid (PUFA) synthase enzymes turn out to be far more versatile than we ever imagined! In our new preprint, we reveal a largely untapped biosynthetic space where they team up with PKSs and NRPSs to create new types of bioactive amphiphilic metabolites.
👉http://bit.ly/4hzUUak
👉http://bit.ly/4hzUUak
Reposted by Masschelein Lab
Last chance to join the #Microbes25 party. Join us to explore how microbial cell factories, synthetic biology, and microbial engineering are rewriting the rulebook of applied #microbiology. Final registration is 23 Oct, grab your spot before it's gone:https://vibbio.tech/3KyHcIb
#VIBConf
#VIBConf
October 7, 2025 at 1:05 PM
Last chance to join the #Microbes25 party. Join us to explore how microbial cell factories, synthetic biology, and microbial engineering are rewriting the rulebook of applied #microbiology. Final registration is 23 Oct, grab your spot before it's gone:https://vibbio.tech/3KyHcIb
#VIBConf
#VIBConf
🚨 Tired of redundant #BiosyntheticGeneCluster hits?
💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT.
Now out in Bioinformatics: bit.ly/3TghJEx
🔗 GitHub: bit.ly/44rNZK9
🙌 Kudos to our PhD student Lucas!
💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT.
Now out in Bioinformatics: bit.ly/3TghJEx
🔗 GitHub: bit.ly/44rNZK9
🙌 Kudos to our PhD student Lucas!
CAGEcleaner: reducing genomic redundancy in gene cluster mining
AbstractMotivation. Mining homologous biosynthetic gene clusters (BGCs) typically involves searching colocalised genes against large genomic databases. How
bit.ly
June 27, 2025 at 2:26 PM
🚨 Tired of redundant #BiosyntheticGeneCluster hits?
💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT.
Now out in Bioinformatics: bit.ly/3TghJEx
🔗 GitHub: bit.ly/44rNZK9
🙌 Kudos to our PhD student Lucas!
💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT.
Now out in Bioinformatics: bit.ly/3TghJEx
🔗 GitHub: bit.ly/44rNZK9
🙌 Kudos to our PhD student Lucas!
Reposted by Masschelein Lab
🥳 Huge congratulations to Prof. Joleen Masschelein (@masscheleinlab.bsky.social, @viblifesciences.bsky.social, @kuleuvenuniversity.bsky.social) for being awarded the 2025 EFMC Academia Prize!
The EFMC proudly announces Prof. Joleen Masschelein (KU Leuven, BE) as the winner of the 2025 EFMC Academia Prize.
Dr Johannes Broichhagen (FMP, DE) and Dr Marta Artola (Leiden University, NL) are recognized as runners-up.
Dr Johannes Broichhagen (FMP, DE) and Dr Marta Artola (Leiden University, NL) are recognized as runners-up.
May 9, 2025 at 12:44 PM
🥳 Huge congratulations to Prof. Joleen Masschelein (@masscheleinlab.bsky.social, @viblifesciences.bsky.social, @kuleuvenuniversity.bsky.social) for being awarded the 2025 EFMC Academia Prize!
The new #antiSMASH v8 paper is out in @narjournal.bsky.social! It was a pleasure helping to improve the detection of bacterial polyyne biosynthetic gene clusters. Happy mining! 🧬🔍
We're happy to announce that the #antiSMASH v8 paper is out in @narjournal.bsky.social: academic.oup.com/nar/advance-...
Many thanks to @kblin.bsky.social, @marnixmedema.bsky.social and many international collaborators!
Many thanks to @kblin.bsky.social, @marnixmedema.bsky.social and many international collaborators!
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
Abstract. Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in
academic.oup.com
April 28, 2025 at 10:10 PM
The new #antiSMASH v8 paper is out in @narjournal.bsky.social! It was a pleasure helping to improve the detection of bacterial polyyne biosynthetic gene clusters. Happy mining! 🧬🔍
Reposted by Masschelein Lab
We are so happy to share that the 2nd Emerging Microbial Technologies conference will take place in Gent next 25th April 2025!!
This edition is jointly organized by CMET_UGENT and YBSMicrobiology
Follow us also on LinkedIn and X @EMT_conference
This edition is jointly organized by CMET_UGENT and YBSMicrobiology
Follow us also on LinkedIn and X @EMT_conference
December 5, 2024 at 11:39 AM
We are so happy to share that the 2nd Emerging Microbial Technologies conference will take place in Gent next 25th April 2025!!
This edition is jointly organized by CMET_UGENT and YBSMicrobiology
Follow us also on LinkedIn and X @EMT_conference
This edition is jointly organized by CMET_UGENT and YBSMicrobiology
Follow us also on LinkedIn and X @EMT_conference
🎄✨ Festive vibes at our annual lab Christmas dinner! Great food and lots of laughter to wrap up a wonderful year of science and teamwork. Here's to more discoveries and collaborations in the year ahead! 🧫🔬
December 14, 2024 at 3:47 PM
🎄✨ Festive vibes at our annual lab Christmas dinner! Great food and lots of laughter to wrap up a wonderful year of science and teamwork. Here's to more discoveries and collaborations in the year ahead! 🧫🔬
Two weeks ago, we had the pleasure to welcome @nadineziemert.bsky.social as a guest speaker at our Microbes & Booze seminar. She gave a very inspiring talk on mining genomes for new antibiotics - thanks for your visit! 💊🍻
November 19, 2024 at 11:58 AM
Two weeks ago, we had the pleasure to welcome @nadineziemert.bsky.social as a guest speaker at our Microbes & Booze seminar. She gave a very inspiring talk on mining genomes for new antibiotics - thanks for your visit! 💊🍻