Mario Kddb
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mario-kddb.bsky.social
Mario Kddb
@mario-kddb.bsky.social
PhD Student on Foundation Models in Microscopy @HTW-Berlin
We developed a method to fine-tune synthetic microscopy images to closely match real ones + pixel-perfect segmentation masks included.

Bridging the gap between synthetic and real data when labels are scarce.

Preprint: datexis.github.io/SynthMT-proj...
Synthetic Data Enables Human-Grade Microtubule Analysis with Foundation Models for Segmentation
datexis.github.io
January 15, 2026 at 6:23 PM
Our preprint is online ⬇️
Synthetic data enables human-grade microtubule analysis with foundation models for segmentation https://www.biorxiv.org/content/10.64898/2026.01.09.698597v1
January 12, 2026 at 8:26 PM
#SAM3 is getting a lot of attention, but how well does it work in specialized domains?

On microscopy data, it performs surprisingly well without any fine-tuning — just careful hyperparameter tuning. In fact, it reaches the same level of agreement as two human annotators.

#Preprint (under review)
January 12, 2026 at 2:05 PM
🐤
January 11, 2026 at 2:01 PM
I used to think: "uv is fast, but is package installation really a bottleneck?"

Then I destroyed my conda env at 11pm while trying to fix a plot for a paper due tomorrow.

Now I get it. uv is incredible 😅

#Python #DevTools
January 10, 2026 at 10:34 PM
First ML+BIO paper of my PhD journey submitted 🎉

Can't wait to receive the bioRxiv link to share our findings!
January 9, 2026 at 9:39 PM
Thank you @overleaf.com for making collaboration so easy!

Just completed a paper with 5+ actively writing/reviewing authors where we worked through 300+ comments. Real-time editing with multiple people working on the same sections without a hitch.

Great piece of software :)
January 8, 2026 at 10:27 PM