Marie Winz
@mariewinz.bsky.social
RNA biologist at Johannes Gutenberg University Mainz, Germany: co-translational quality control - RNA modification - and beyond.
Lab url: ak-winz.pharmazie.uni-mainz.de
Lab url: ak-winz.pharmazie.uni-mainz.de
Reposted by Marie Winz
New preprint: We isolate peptide–RNA photo-crosslinks with tunable RNA chains from living cells for mass spec. This maps over 4,700 crosslinking sites across 744 proteins and offers the first glimpse into the RNA sequences in crosslinks by MS. Read here: doi.org/10.1101/2025...
Peptide-RNA photo-crosslinks with tunable RNA chain map protein-RNA interfaces
Photo-crosslinking mass spectrometry enables the identification of protein-RNA interactions in living cells, pinpointing interaction interfaces at single-amino acid resolution. However, current isolat...
doi.org
September 9, 2025 at 11:46 AM
New preprint: We isolate peptide–RNA photo-crosslinks with tunable RNA chains from living cells for mass spec. This maps over 4,700 crosslinking sites across 744 proteins and offers the first glimpse into the RNA sequences in crosslinks by MS. Read here: doi.org/10.1101/2025...
Reposted by Marie Winz
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress https://www.biorxiv.org/content/10.1101/2025.09.04.673968v1
September 9, 2025 at 6:17 PM
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress https://www.biorxiv.org/content/10.1101/2025.09.04.673968v1
September 9, 2025 at 6:17 PM
Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
Reposted by Marie Winz
Thrilled to share my first last-author paper, just out in #mSystems! A work about #RBPs, #RNA and #sporulation in #subtilis.
Special thanks to my brilliant student T. Kaboré who's signing hist first PhD paper and to the whole team @galinier-lab.bsky.social
👉 journals.asm.org/doi/10.1128/...
Special thanks to my brilliant student T. Kaboré who's signing hist first PhD paper and to the whole team @galinier-lab.bsky.social
👉 journals.asm.org/doi/10.1128/...
Remodeling of RNA-binding proteome and RNA-mediated regulation as a new layer of control of sporulation | mSystems
Understanding how bacteria survive extreme conditions is key to tackling challenges
in health, food safety, and industry. This study reveals a previously unexplored layer
of control in Bacillus subtil...
journals.asm.org
August 18, 2025 at 11:30 AM
Thrilled to share my first last-author paper, just out in #mSystems! A work about #RBPs, #RNA and #sporulation in #subtilis.
Special thanks to my brilliant student T. Kaboré who's signing hist first PhD paper and to the whole team @galinier-lab.bsky.social
👉 journals.asm.org/doi/10.1128/...
Special thanks to my brilliant student T. Kaboré who's signing hist first PhD paper and to the whole team @galinier-lab.bsky.social
👉 journals.asm.org/doi/10.1128/...
#proudPI moment yesterday, seeing my PhD student @kaushikiyer.bsky.social ace his talk at #EMBLProtein conference, presenting his work on new translation quality control factor Jlp2. Really did a great job holding up our lab's flag!!! 😄
September 5, 2025 at 12:43 PM
#proudPI moment yesterday, seeing my PhD student @kaushikiyer.bsky.social ace his talk at #EMBLProtein conference, presenting his work on new translation quality control factor Jlp2. Really did a great job holding up our lab's flag!!! 😄
Reposted by Marie Winz
Postdoc positions in structural biology of RNA processing complexes.
An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification.
Details: tinyurl.com/postdoc-RNA-...
An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification.
Details: tinyurl.com/postdoc-RNA-...
Postdoc in Structural Biology of RNA processing complexes
Postdoctoral positions in structural biology of macromolecular complexes are available in the laboratory of Dr. Eva Kowalinski at the EMBL Grenoble, France. We are looking for highly motivated and amb...
tinyurl.com
July 17, 2025 at 9:50 AM
Postdoc positions in structural biology of RNA processing complexes.
An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification.
Details: tinyurl.com/postdoc-RNA-...
An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification.
Details: tinyurl.com/postdoc-RNA-...
Reposted by Marie Winz
🚨 New preprint! 🚨
We just dropped our latest work on RNA-binding proteins and sporulation in B. subtilis! Turns out, the RBP landscape gets a major remix during sporulation 👀. Check it out here 👉 www.biorxiv.org/content/10.1...
#RBP #RNA #sporulation #Bacillus #microbiology @lcbofficiel.bsky.social
We just dropped our latest work on RNA-binding proteins and sporulation in B. subtilis! Turns out, the RBP landscape gets a major remix during sporulation 👀. Check it out here 👉 www.biorxiv.org/content/10.1...
#RBP #RNA #sporulation #Bacillus #microbiology @lcbofficiel.bsky.social
Remodeling of RNA-Binding Proteome and RNA-mediated regulation as a new layer of control of sporulation
Sporulation allows certain bacteria to survive extreme conditions for extended periods posing challenges to public health and food safety. Transcriptional level of regulation relying on σ factors has ...
www.biorxiv.org
April 15, 2025 at 9:27 AM
🚨 New preprint! 🚨
We just dropped our latest work on RNA-binding proteins and sporulation in B. subtilis! Turns out, the RBP landscape gets a major remix during sporulation 👀. Check it out here 👉 www.biorxiv.org/content/10.1...
#RBP #RNA #sporulation #Bacillus #microbiology @lcbofficiel.bsky.social
We just dropped our latest work on RNA-binding proteins and sporulation in B. subtilis! Turns out, the RBP landscape gets a major remix during sporulation 👀. Check it out here 👉 www.biorxiv.org/content/10.1...
#RBP #RNA #sporulation #Bacillus #microbiology @lcbofficiel.bsky.social
Reposted by Marie Winz
Online Now: UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains Online now:
UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains
Ubiquitin chains determine the fates of their modified proteins, including proteasomal degradation. Kiss et al. present UbiREAD, a technology to monitor cellular degradation and deubiquitination at high temporal resolution after intracellular delivery of ubiquitinated proteins. This reveals a degradation code for ubiquitin chains varying by linkage, length, and topology.
dlvr.it
March 26, 2025 at 10:57 PM
Online Now: UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains Online now:
Paper alert 🚨 Check out our new paper about RNA polymerase I termination! Great collaboration with
Liz Petfalski, Katarzyna Grelewska-Nowotko and David Tollervey!
online yesterday in @CellReports! It took a while but finally come to life! t.co/5RPpxAhRvU
It was a pleasure to contribute!
Liz Petfalski, Katarzyna Grelewska-Nowotko and David Tollervey!
online yesterday in @CellReports! It took a while but finally come to life! t.co/5RPpxAhRvU
It was a pleasure to contribute!
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00096-8
t.co
February 25, 2025 at 6:32 PM
Paper alert 🚨 Check out our new paper about RNA polymerase I termination! Great collaboration with
Liz Petfalski, Katarzyna Grelewska-Nowotko and David Tollervey!
online yesterday in @CellReports! It took a while but finally come to life! t.co/5RPpxAhRvU
It was a pleasure to contribute!
Liz Petfalski, Katarzyna Grelewska-Nowotko and David Tollervey!
online yesterday in @CellReports! It took a while but finally come to life! t.co/5RPpxAhRvU
It was a pleasure to contribute!