Maria Gubbiotti, MD,PhD
@mariagoobs.bsky.social
Neuropathologist at MD Anderson Cancer Center 🧠🔬Amateur Equine Enthusiast 🦄
Opinions are my own and are not reflective of my employer nor are they medical advice
#medsky #pathsky #eqbsky 🐎 🦋
Opinions are my own and are not reflective of my employer nor are they medical advice
#medsky #pathsky #eqbsky 🐎 🦋
Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky
October 22, 2025 at 4:00 PM
Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky
October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky
October 2, 2025 at 12:00 AM
October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky
Dural-based mass with dural tail
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
June 13, 2025 at 6:39 PM
Dural-based mass with dural tail
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social
April 4, 2025 at 7:52 PM
Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social
In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky
February 11, 2025 at 9:35 PM
In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky
Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠
January 19, 2025 at 8:58 PM
Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
January 2, 2025 at 3:12 PM
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
Asteroid hyalosis is an aging-associated condition of the eye where calcium and phospholipids build up giving the eye a grossly “glittery star-like” appearance (hence the name). Here is a vitreous cytology specimen before and after polarization showing the material 💫 👁️ #pathsky #medsky
December 20, 2024 at 3:24 PM
Some tumor look-a-likes on this Friday:
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
December 6, 2024 at 5:46 PM
Some tumor look-a-likes on this Friday:
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
Alternatively, if you are looking for something else consider mailchi.mp/houserabbits...
This is where we adopted our adorable bunny Teepah!
This is where we adopted our adorable bunny Teepah!
December 3, 2024 at 4:55 PM
Alternatively, if you are looking for something else consider mailchi.mp/houserabbits...
This is where we adopted our adorable bunny Teepah!
This is where we adopted our adorable bunny Teepah!
Happy Thanksgiving! Always a time to reflect and be grateful for where we are, where we’ve been, and where we are going 😊 🦃
November 28, 2024 at 1:47 PM
Happy Thanksgiving! Always a time to reflect and be grateful for where we are, where we’ve been, and where we are going 😊 🦃
#worldprematurityday2024
Our daughter was born at 28 weeks and is now a happy healthy almost 3 year old! @mjcampbell.bsky.social was amazing and handily played both doctor and dad roles!
Fun fact: my dad was also born prematurely (both born in December). Wild to see his picture next to hers!
Our daughter was born at 28 weeks and is now a happy healthy almost 3 year old! @mjcampbell.bsky.social was amazing and handily played both doctor and dad roles!
Fun fact: my dad was also born prematurely (both born in December). Wild to see his picture next to hers!
November 18, 2024 at 2:31 AM
#worldprematurityday2024
Our daughter was born at 28 weeks and is now a happy healthy almost 3 year old! @mjcampbell.bsky.social was amazing and handily played both doctor and dad roles!
Fun fact: my dad was also born prematurely (both born in December). Wild to see his picture next to hers!
Our daughter was born at 28 weeks and is now a happy healthy almost 3 year old! @mjcampbell.bsky.social was amazing and handily played both doctor and dad roles!
Fun fact: my dad was also born prematurely (both born in December). Wild to see his picture next to hers!
According to my husband I only have two interests: surgical pathology and horses 😂
This is my OTTB, When You Wish (name credits to @mjcampbell.bsky.social) “Star” who was given to me 7 years ago by one of my early horse mentors (it’s a long story lol). Anyway I love her to pieces #eqbsky 🐎🦋
This is my OTTB, When You Wish (name credits to @mjcampbell.bsky.social) “Star” who was given to me 7 years ago by one of my early horse mentors (it’s a long story lol). Anyway I love her to pieces #eqbsky 🐎🦋
November 16, 2024 at 9:37 PM
According to my husband I only have two interests: surgical pathology and horses 😂
This is my OTTB, When You Wish (name credits to @mjcampbell.bsky.social) “Star” who was given to me 7 years ago by one of my early horse mentors (it’s a long story lol). Anyway I love her to pieces #eqbsky 🐎🦋
This is my OTTB, When You Wish (name credits to @mjcampbell.bsky.social) “Star” who was given to me 7 years ago by one of my early horse mentors (it’s a long story lol). Anyway I love her to pieces #eqbsky 🐎🦋
It’s almost Friday so here’s a case of metastatic papillary thyroid carcinoma that now shows anaplastic transformation. The late great Dr Livolsi and I did a study on such brain metastases detailing the histologic and molecular features ❤️🧠🔬 #pathsky
pubmed.ncbi.nlm.nih.gov/36889238/
pubmed.ncbi.nlm.nih.gov/36889238/
November 14, 2024 at 1:46 PM
It’s almost Friday so here’s a case of metastatic papillary thyroid carcinoma that now shows anaplastic transformation. The late great Dr Livolsi and I did a study on such brain metastases detailing the histologic and molecular features ❤️🧠🔬 #pathsky
pubmed.ncbi.nlm.nih.gov/36889238/
pubmed.ncbi.nlm.nih.gov/36889238/
Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath
November 11, 2024 at 7:59 PM
Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath
Though I used the previous platform solely for medical posts, here is some horse content for #eqbsky 🐎 🦋
Introducing me, Star, and @mjcampbell.bsky.social (follow for pediatric cardiology content!)
I especially love this picture because our daughter Madeline (now a toddler lol) is also in it
Introducing me, Star, and @mjcampbell.bsky.social (follow for pediatric cardiology content!)
I especially love this picture because our daughter Madeline (now a toddler lol) is also in it
November 10, 2024 at 4:38 PM
Though I used the previous platform solely for medical posts, here is some horse content for #eqbsky 🐎 🦋
Introducing me, Star, and @mjcampbell.bsky.social (follow for pediatric cardiology content!)
I especially love this picture because our daughter Madeline (now a toddler lol) is also in it
Introducing me, Star, and @mjcampbell.bsky.social (follow for pediatric cardiology content!)
I especially love this picture because our daughter Madeline (now a toddler lol) is also in it
Nice example of a schwannoma including an intact gross specimen and H&E stained sections showing Verocay body formation and some ancient change 🧠 🔬
November 9, 2024 at 6:06 PM
Nice example of a schwannoma including an intact gross specimen and H&E stained sections showing Verocay body formation and some ancient change 🧠 🔬
Thanks! I mostly used Twitter for pathology related things but also scrolled through horse twitter for fun lol will try to make it a mix here! Here’s my girl, Star
November 9, 2024 at 5:50 PM
Thanks! I mostly used Twitter for pathology related things but also scrolled through horse twitter for fun lol will try to make it a mix here! Here’s my girl, Star
Starting off with a path classic of adenoid cystic carcinoma
November 7, 2024 at 6:42 PM
Starting off with a path classic of adenoid cystic carcinoma