Marco Stock
@marcostock.bsky.social
PhD student @ Helmholtz Munich
Reposted by Marco Stock
Great team effort, led by @marcostock.bsky.social , with Corinna Losert, @mattezambon.bsky.social, Niclas Popp, Gabriele Lubatti, @evahoermanseder.bsky.social & Matthias Heinig
February 12, 2025 at 8:05 PM
Great team effort, led by @marcostock.bsky.social , with Corinna Losert, @mattezambon.bsky.social, Niclas Popp, Gabriele Lubatti, @evahoermanseder.bsky.social & Matthias Heinig
Reposted by Marco Stock
✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development
In the life of a vertebrate embryo, gene expression is initiated for the first time at zygotic genome activation (ZGA). Maternally expressed transcription factors present in the embryo are essential f...
doi.org
January 22, 2025 at 1:56 PM
✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
Reposted by Marco Stock
UMAP applied to 100 randomly generated points from a multivariate normal distribution
simplystatistics.org/posts/2024-1...
simplystatistics.org/posts/2024-1...
December 23, 2024 at 1:57 PM
UMAP applied to 100 randomly generated points from a multivariate normal distribution
simplystatistics.org/posts/2024-1...
simplystatistics.org/posts/2024-1...
Reposted by Marco Stock
We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
December 23, 2024 at 8:43 AM
We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
Reposted by Marco Stock
Learning on graphs 2024 recordings are all available online: youtube.com/watch?v=Af-_...
logconference.org what a great resource!
logconference.org what a great resource!
youtube.com
December 1, 2024 at 10:46 PM
Learning on graphs 2024 recordings are all available online: youtube.com/watch?v=Af-_...
logconference.org what a great resource!
logconference.org what a great resource!
Reposted by Marco Stock
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
www.nature.com
November 27, 2024 at 4:13 AM
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...