Mapping Ignorance
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mappingignorance.org
Mapping Ignorance
@mappingignorance.org
🔹A research blog by the Chair of Scientific Culture of the University of the Basque Country (@katedra.eus)

🔗 https://mappingignorance.org/
A new tube plasma ion source for LC-MS was developed in this #EHUikerketa, and compared with established ion sources (ESI and APCI) for sterol analysis.

Sterol analysis in cancer cells using atmospheric pressure ionization techniques - Analytical and Bioanalytical Chemistry
The analysis of sterol biosynthesis poses analytical challenges such as vast concentration differences between precursor molecules and cholesterol as well as the substantial interferences between the sterols and the matrix, resulting in strong ion suppression. LC-MS and 2D-LC-MS may address some of these challenges, but for sensitive and robust detection, ionization plays a key role. Electrospray ionization (ESI) stands out for its capability to generate ions from polar and nonpolar compounds, rendering it suitable for a broad spectrum of analytes, including sterols. Atmospheric pressure chemical ionization (APCI) demonstrates efficacy for compounds exhibiting moderate to low polarity, thereby facilitating efficient ionization of sterols. Tube plasma ionization (TPI) is a relatively new technique that promises sensitive ionization across a wide polarity range, indicating its potential utility for sterol analysis. Here, a new tube plasma ion source for LC-MS was developed and compared with established ion sources (ESI and APCI) for sterol analysis. The TPI source showed comparable LOQs to APCI and clearly outperformed ESI in terms of sensitivity. Both TPI and APCI provided stable signals during extended measurement series, while ESI suffered from pronounced ion suppression. Application to human plasma, HepG2 cells, and liver tissue demonstrated that TPI provided results in close agreement with APCI, highlighting its robustness for sterol quantification in complex biological matrices. Graphical abstract
link.springer.com
November 29, 2025 at 10:06 PM
This #EHUikerketa evaluates whether native forest restorations in the Urdaibai Biosphere Reserve support higher biodiversity and ecosystem functioning compared to the most abundant forest systems in the area. 

Multitaxon biodiversity and functional recovery in restored native forests in a biosphere reserve
Forest landscapes in Europe have historically undergone extensive anthropogenic transformation, leading to the widespread replacement of native forest…
www.sciencedirect.com
November 29, 2025 at 9:05 PM
This #EHUikerketa introduces a novel approach by combining data from regulatory reports with a meta-analysis to derive dose-response curves for population-relevant parameters. 

A simplified landscape-based approach for including agronomical and ecological characteristic in pesticide risk assessments for terrestrial vertebrates
Pesticides have played a crucial role in enhancing food production, although their intensive application poses significant threats to ecosystems and m…
www.sciencedirect.com
November 28, 2025 at 10:06 PM
This #EHUikerketa is a population-based study of methadone-induced deaths (2003–2022) and associated risk factors.

Assessment of risk factors associated with methadone-induced deaths: A population study based on forensic autopsies (2003–2022)
Population-based study of methadone-induced deaths (2003–2022) and associated risk factors.All deaths with blood presence of methadone and forensic au…
www.sciencedirect.com
November 28, 2025 at 9:05 PM
The aim of this #EHUikerketa was to evaluate the association of APS and SLE, focusing on LN, with risk of pre-eclampsia (PE) and PE with severity criteria (PESC).

academic.oup.com
November 28, 2025 at 8:05 PM
In CsV₃Sb₅, electrons do not merely scatter, they conspire, turning what should be incoherent hopping into a micrometer-scale quantum symphony whose notes are tuned by magnetic flux.

Giant collective Aharonov–Bohm oscillations in CsV₃Sb₅
In CsV₃Sb₅ robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers.
mappingignorance.org
November 28, 2025 at 5:06 AM
The only way to explain the data is that the electrons are moving collectively, carrying a shared quantum phase that survives scattering and spans the whole device.

https://mappingignorance.org/2025/11/27/giant-collective-aharonov-bohm-oscillations-in-a-kagome-metal/
November 28, 2025 at 3:05 AM
In the layered kagome metal CsV₃Sb₅, researchers have observed robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers. 

Giant collective Aharonov–Bohm oscillations in CsV₃Sb₅
In CsV₃Sb₅ robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers.
mappingignorance.org
November 28, 2025 at 1:06 AM
In CsV₃Sb₅, electrons do not merely scatter, they conspire, turning what should be incoherent hopping into a micrometer-scale quantum symphony whose notes are tuned by magnetic flux.

Giant collective Aharonov–Bohm oscillations in CsV₃Sb₅
In CsV₃Sb₅ robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers.
mappingignorance.org
November 27, 2025 at 8:06 PM
Platinum atoms on epitaxial graphene behave like tiny skaters on an almost frictionless rink (even at temperatures where most atomic motion should be frozen). 

Fast HR-XPS reveals the mobility of platinum atoms on graphene
Fast HR-XPS has turned what was once an invisible, fleeting process into something measurable, understandable, and ultimately controllable.
mappingignorance.org
November 27, 2025 at 7:05 PM
The only way to explain the data is that the electrons are moving collectively, carrying a shared quantum phase that survives scattering and spans the whole device.

https://mappingignorance.org/2025/11/27/giant-collective-aharonov-bohm-oscillations-in-a-kagome-metal/
November 27, 2025 at 6:05 PM
What makes the result so convincing is how fast HR-XPS enabled a full kinetic reconstruction of the aggregation process. 

Fast HR-XPS reveals the mobility of platinum atoms on graphene
Fast HR-XPS has turned what was once an invisible, fleeting process into something measurable, understandable, and ultimately controllable.
mappingignorance.org
November 27, 2025 at 5:06 PM
In the layered kagome metal CsV₃Sb₅, researchers have observed robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers. 

Giant collective Aharonov–Bohm oscillations in CsV₃Sb₅
In CsV₃Sb₅ robust quantum interference in the normal, non-superconducting state, persisting over distances of several micrometers.
mappingignorance.org
November 27, 2025 at 4:05 PM
Platinum atoms on epitaxial graphene (a single, perfectly ordered layer of carbon atoms grown on an iridium crystal), turned out to move far more easily than anyone expected.

Fast HR-XPS reveals the mobility of platinum atoms on graphene
Fast HR-XPS has turned what was once an invisible, fleeting process into something measurable, understandable, and ultimately controllable.
mappingignorance.org
November 27, 2025 at 3:06 PM
November 27, 2025 at 2:03 PM
Addressing the paradox of cleaner air uncovering hidden warming demands integrating air-quality and climate policy and accelerating the reduction of greenhouse gases.

Reduced air pollution is making clouds reflect less sunlight
Global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds
mappingignorance.org
November 27, 2025 at 5:06 AM
While cleaner air has major health benefits, decreasing the amount of particulate pollution has also reduced the cooling effect of clouds, accelerating climate warming.

https://mappingignorance.org/2025/11/26/reduced-air-pollution-is-making-clouds-reflect-less-sunlight/
November 27, 2025 at 3:05 AM
A research shows global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds.

Reduced air pollution is making clouds reflect less sunlight
Global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds
mappingignorance.org
November 27, 2025 at 1:06 AM
Addressing the paradox of cleaner air uncovering hidden warming demands integrating air-quality and climate policy and accelerating the reduction of greenhouse gases.

Reduced air pollution is making clouds reflect less sunlight
Global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds
mappingignorance.org
November 26, 2025 at 8:06 PM
In a sense, Monte Sierpe may have functioned as a large “spreadsheet” for the Inca Empire.

A centuries-old grid of holes in Monte Sierpe (Andes) for accounting
“Pockmarks” in the Pisco Valley of southern Peru make up the mysterious archaeological site of Monte Sierpe
mappingignorance.org
November 26, 2025 at 7:05 PM
While cleaner air has major health benefits, decreasing the amount of particulate pollution has also reduced the cooling effect of clouds, accelerating climate warming.

https://mappingignorance.org/2025/11/26/reduced-air-pollution-is-making-clouds-reflect-less-sunlight/
November 26, 2025 at 6:05 PM
Monte Sierpe, which dates to at least 700 years ago, may have functioned as an Indigenous system of accounting and exchange.

https://mappingignorance.org/2025/11/19/a-centuries-old-grid-of-holes-in-the-andes-may-have-been-a-spreadsheet-for-accounting-and-exchange/
November 26, 2025 at 5:05 PM
A research shows global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds.

Reduced air pollution is making clouds reflect less sunlight
Global efforts to improve air quality have unintentionally accelerated climate warming by modifying clouds
mappingignorance.org
November 26, 2025 at 4:06 PM
Stretching 1.5 kilometres and consisting of approximately 5,200 precisely aligned holes, Monte Sierpe translates as “serpent mountain” in Spanish.

https://mappingignorance.org/2025/11/19/a-centuries-old-grid-of-holes-in-the-andes-may-have-been-a-spreadsheet-for-accounting-and-exchange/
November 26, 2025 at 3:05 PM