Manuel San Silvestre
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manuelricofss.bsky.social
Manuel San Silvestre
@manuelricofss.bsky.social
MD and MSc in Neuroscience student @ox.ac.uk

Figuring out what the cerebellum does 🧠
Reposted by Manuel San Silvestre
🔊NEW RESEARCH: Shame plays a major role in hairpulling, a type of body-focused repetitive behaviour (BFRB), among young people, according to a study by @ox.ac.uk

Read more 👉 tinyurl.com/ajjxz7rz

@claremackay.bsky.social @pollywaite.bsky.social #BFRBs @acamh.bsky.social @oxhealthbrc.bsky.social
November 10, 2025 at 9:23 AM
Reposted by Manuel San Silvestre
The ApoE2, longevity & cognitive resilience triad raises the tantalizing (& least understood relationship) possibility that cognitive resilience may promote lifespan, as suggested by cognitively resilient centenarians (100-plus study). Identities of mechanisms remain elusive. 1/2
alz-journals.onlinelibrary.wiley.com
January 16, 2026 at 9:45 PM
Reposted by Manuel San Silvestre
would result in a DG optimized to flexibly recruit new neurons to generate distinct representations. GABAergic inhibition-dep. reduction of interference btw memory indexes preserved their integrity. This study explains how this obviates need for pattern separation.
www.nature.com/articles/s41...
Client Challenge
www.nature.com
January 14, 2026 at 4:51 PM
Reposted by Manuel San Silvestre
With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.

My hope is that this will be a living document, continuously improved as I get feedback.
January 9, 2026 at 1:27 AM