These rare conditions affect the muscles and can impact walking, eating, sleeping and breathing.
Bringing together leading experts we will push research forwards, faster.🧑🔬
#musculardystrophy #genetherapy
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
Discussions focused on:
• Improving AAV delivery for gene therapy
• Gene editing beyond mutation correction
• 3D muscle models to accelerate testing
Read more: magic-horizon.eu/news/magic-g...
Discussions focused on:
• Improving AAV delivery for gene therapy
• Gene editing beyond mutation correction
• 3D muscle models to accelerate testing
Read more: magic-horizon.eu/news/magic-g...
PI
@SaverioTedesco
shares how this multi-partner project tackles key challenges in rare neuromuscular conditions – building building tools for safer, more effective treatments.
🎥 Watch below
#GeneTherapy #RareDisease
PI
@SaverioTedesco
shares how this multi-partner project tackles key challenges in rare neuromuscular conditions – building building tools for safer, more effective treatments.
🎥 Watch below
#GeneTherapy #RareDisease
Our workshop brought researchers together for a Q&A with MAGIC experts Eduard Ayuso, David-Alexandre Gross, Gabriela Silve & Odile Boespflug-Tanguy.
From delivery challenges to emerging tech, the future looks bold.
#GeneTherapy
Our workshop brought researchers together for a Q&A with MAGIC experts Eduard Ayuso, David-Alexandre Gross, Gabriela Silve & Odile Boespflug-Tanguy.
From delivery challenges to emerging tech, the future looks bold.
#GeneTherapy
Consortium partners are gathering to:
✅ Share progress
✅ Strengthen collaboration
✅ Align on next steps
We’re driving innovation in neuromuscular disease & gene therapy – and building momentum for the year ahead. 🚀
#ResearchProgress
Consortium partners are gathering to:
✅ Share progress
✅ Strengthen collaboration
✅ Align on next steps
We’re driving innovation in neuromuscular disease & gene therapy – and building momentum for the year ahead. 🚀
#ResearchProgress
🔬Muscle on a Chip
🧬Gene Editing
💉Viral Transduction
🧫Vector Production
We're sharing knowledge with the wider research community to accelerate progress in #genetherapy.
🔬Muscle on a Chip
🧬Gene Editing
💉Viral Transduction
🧫Vector Production
We're sharing knowledge with the wider research community to accelerate progress in #genetherapy.
@crick.ac.uk
shared 3 posters on human models for neuromuscular gene therapy:
🧪 3D cultures for DMD
🧠 AAV dynamics in multi-organoids
🧬 Myotubular myopathy modelling
Pushing boundaries in patient-relevant research.
#genetherapy #MagicProject
@crick.ac.uk
shared 3 posters on human models for neuromuscular gene therapy:
🧪 3D cultures for DMD
🧠 AAV dynamics in multi-organoids
🧬 Myotubular myopathy modelling
Pushing boundaries in patient-relevant research.
#genetherapy #MagicProject
DINAMIQS shared how mass photometry boosts AAV packaging efficiency & stability.
📌 >95% full capsids = better stress resilience.
🚀 Fast, label-free AAV quality checks = smarter upstream optimisation.
#MAGICProject #GeneTherapy #AAV
DINAMIQS shared how mass photometry boosts AAV packaging efficiency & stability.
📌 >95% full capsids = better stress resilience.
🚀 Fast, label-free AAV quality checks = smarter upstream optimisation.
#MAGICProject #GeneTherapy #AAV
Fantastic to see this international collaboration represented on the global stage 🌍🧬
#genetherapy #3Dmusclemodels
Fantastic to see this international collaboration represented on the global stage 🌍🧬
#genetherapy #3Dmusclemodels
Make sure you check out the presentations from MAGIC members to learn more about the project and how we’re aiming to accelerate the development of gene therapies for rare neuromuscular conditions.
🧵⬇️
Make sure you check out the presentations from MAGIC members to learn more about the project and how we’re aiming to accelerate the development of gene therapies for rare neuromuscular conditions.
🧵⬇️
Members from MAGIC will be attending both – keep an eye out for posters and presentations to learn more about the project.
We’re looking forward to connecting with researchers, clinicians, and collaborators across both events! 🤝
Members from MAGIC will be attending both – keep an eye out for posters and presentations to learn more about the project.
We’re looking forward to connecting with researchers, clinicians, and collaborators across both events! 🤝
🧬 Tailored cell sources
🧱 Custom matrix design
📊 Relevant functional readouts
All within a scalable, reproducible platform.
🔗 magic-horizon.eu
🧬 Tailored cell sources
🧱 Custom matrix design
📊 Relevant functional readouts
All within a scalable, reproducible platform.
🔗 magic-horizon.eu
The MAGIC project unites researchers worldwide to advance next-gen genetic therapies.
Our project leaflets, now in 6 languages, outline our goals and translational potential.
📄 Download: magic-horizon.eu/media/leafle...
#RareDisease
The MAGIC project unites researchers worldwide to advance next-gen genetic therapies.
Our project leaflets, now in 6 languages, outline our goals and translational potential.
📄 Download: magic-horizon.eu/media/leafle...
#RareDisease
🔬 Patient-derived cells
💧 Microfluidics
🧫 3D tissue architecture
Designed to better predict how gene therapies will work in rare neuromuscular diseases.
🔗 magic-horizon.eu
#GeneTherapy
🔬 Patient-derived cells
💧 Microfluidics
🧫 3D tissue architecture
Designed to better predict how gene therapies will work in rare neuromuscular diseases.
🔗 magic-horizon.eu
#GeneTherapy
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
🔬 Lack of realistic muscle models
🧫 Targeted delivery without triggering immune responses
Mariam Zhouhair (@crick.ac.uk) shares how the MAGIC project is tackling these.
🔗 magic-horizon.eu/news/meet-cr...
🔬 Lack of realistic muscle models
🧫 Targeted delivery without triggering immune responses
Mariam Zhouhair (@crick.ac.uk) shares how the MAGIC project is tackling these.
🔗 magic-horizon.eu/news/meet-cr...
Subscribe to hear about the latest developments from the #MAGICproject:
🔬 Genetic therapies advances for muscular dystrophies
📰 Conference & event highlights
📝 New research publications
…& more!
👉 magic-horizon.eu/news-events/...
Subscribe to hear about the latest developments from the #MAGICproject:
🔬 Genetic therapies advances for muscular dystrophies
📰 Conference & event highlights
📝 New research publications
…& more!
👉 magic-horizon.eu/news-events/...
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
The #MAGICproject is publishing impactful research, scientific tools & resources for the wider community.
🧬 Explore open-access papers, abstracts, and key findings here:
👉 magic-horizon.eu
#GeneTherapy #RareDisease
Our team modelled L-CMD, a severe laminopathy, using iPSC-derived skeletal muscle & showed how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
Our team modelled L-CMD, a severe laminopathy, using iPSC-derived skeletal muscle & showed how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
We model L-CMD-a severe laminopathy-using iPSC-derived skeletal muscle & show how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
www.biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
We model L-CMD-a severe laminopathy-using iPSC-derived skeletal muscle & show how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.
www.biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC
The goal: identify & calm early immune responses to boost safety & efficacy.
🔬 Full interview: magic-horizon.eu/news/meet-nu...
#GeneTherapy #AAV
The goal: identify & calm early immune responses to boost safety & efficacy.
🔬 Full interview: magic-horizon.eu/news/meet-nu...
#GeneTherapy #AAV
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
A novel iPSC line from a UCMD patient with a COL6A1 mutation offers a valuable new model for studying collagen VI-related muscular dystrophies and testing therapies.
📖 Read the paper: www.sciencedirect.com/science/arti...
Subscribe to hear the latest updates from the #MAGICproject, such as:
🔬 Advances in genetic therapies for muscular dystrophies
📰 Conference and event highlights
📝 New research publications
…and more!
👉 Sign up: magic-horizon.eu/news-events/...
Subscribe to hear the latest updates from the #MAGICproject, such as:
🔬 Advances in genetic therapies for muscular dystrophies
📰 Conference and event highlights
📝 New research publications
…and more!
👉 Sign up: magic-horizon.eu/news-events/...
Siegfried DINAMIQS supports the #MAGICproject to tackle manufacturing early.
Eduard Ayuso: “...make groundbreaking therapies manufacturable at quality and cost for patients.”
🔗 magic-horizon.eu/news/meet-di...
Siegfried DINAMIQS supports the #MAGICproject to tackle manufacturing early.
Eduard Ayuso: “...make groundbreaking therapies manufacturable at quality and cost for patients.”
🔗 magic-horizon.eu/news/meet-di...