LUMICKS
@lumicks.bsky.social
Empowering scientists with tools that reveal crucial insights not available before, at the molecular and cellular level | Dynamic single-molecule & Cell Avidity
How do our cells untangle their DNA during division? What happens when this process goes wrong? In a new study, Dr Erin Cutts uncovers DNA entanglements during early mitosis in real time at the single-molecule level. Join the upcoming webinar to learn how Erin made these discoveries: bit.ly/48nOhoc
November 19, 2025 at 3:46 PM
How do our cells untangle their DNA during division? What happens when this process goes wrong? In a new study, Dr Erin Cutts uncovers DNA entanglements during early mitosis in real time at the single-molecule level. Join the upcoming webinar to learn how Erin made these discoveries: bit.ly/48nOhoc
Are you working on cell therapy? Looking for a reliable indicator to predict patient outcomes from preclinical immune assays?
👉 Last chance to register for LIVE webinar by Prof. Peter Chockley on how Cell Avidity measurements predict leukemia patient survival after transplant: bit.ly/3JHMzou
👉 Last chance to register for LIVE webinar by Prof. Peter Chockley on how Cell Avidity measurements predict leukemia patient survival after transplant: bit.ly/3JHMzou
November 17, 2025 at 1:52 PM
Are you working on cell therapy? Looking for a reliable indicator to predict patient outcomes from preclinical immune assays?
👉 Last chance to register for LIVE webinar by Prof. Peter Chockley on how Cell Avidity measurements predict leukemia patient survival after transplant: bit.ly/3JHMzou
👉 Last chance to register for LIVE webinar by Prof. Peter Chockley on how Cell Avidity measurements predict leukemia patient survival after transplant: bit.ly/3JHMzou
Can Cell Avidity help predict stem cell transplant success?
Prof. Peter Chockley (The Ohio State University) and his team used Cell Avidity to uncover a previously unknown NK cell–tumor interaction whose strength correlates with patient survival.
Curious? Register for the webinar: bit.ly/3Lov39i
Prof. Peter Chockley (The Ohio State University) and his team used Cell Avidity to uncover a previously unknown NK cell–tumor interaction whose strength correlates with patient survival.
Curious? Register for the webinar: bit.ly/3Lov39i
November 5, 2025 at 4:11 PM
Can Cell Avidity help predict stem cell transplant success?
Prof. Peter Chockley (The Ohio State University) and his team used Cell Avidity to uncover a previously unknown NK cell–tumor interaction whose strength correlates with patient survival.
Curious? Register for the webinar: bit.ly/3Lov39i
Prof. Peter Chockley (The Ohio State University) and his team used Cell Avidity to uncover a previously unknown NK cell–tumor interaction whose strength correlates with patient survival.
Curious? Register for the webinar: bit.ly/3Lov39i
Targeting FACT in cancer cells has shown efficacy in preclinical trials, but by which mechanism? Unclear.
Enter: this new study from the Bustamante Lab at UC Berkeley. It reveals that NDF-FACT condensates form on transcribing PolII and enhance nucleosome disassembly and PolII progression.
Enter: this new study from the Bustamante Lab at UC Berkeley. It reveals that NDF-FACT condensates form on transcribing PolII and enhance nucleosome disassembly and PolII progression.
October 3, 2025 at 10:41 AM
Targeting FACT in cancer cells has shown efficacy in preclinical trials, but by which mechanism? Unclear.
Enter: this new study from the Bustamante Lab at UC Berkeley. It reveals that NDF-FACT condensates form on transcribing PolII and enhance nucleosome disassembly and PolII progression.
Enter: this new study from the Bustamante Lab at UC Berkeley. It reveals that NDF-FACT condensates form on transcribing PolII and enhance nucleosome disassembly and PolII progression.
Finding the right CAR affinity is tricky: too low fails, too high impairs function. Measuring cell avidity helps define the productive window, where affinity + avidity drive CAR clustering, persistence & efficacy.
👉 Join Dr. Markus Barden: bit.ly/464vLyZ
👉 Join Dr. Markus Barden: bit.ly/464vLyZ
September 17, 2025 at 12:47 PM
Finding the right CAR affinity is tricky: too low fails, too high impairs function. Measuring cell avidity helps define the productive window, where affinity + avidity drive CAR clustering, persistence & efficacy.
👉 Join Dr. Markus Barden: bit.ly/464vLyZ
👉 Join Dr. Markus Barden: bit.ly/464vLyZ
TODAY: Discover how Prof. Taekjip Ha (Harvard University) used the LUMICKS C-Trap to uncover real-time dynamics of chromatin remodelers and transcription factors at the single-molecule level.
Join the webinar: bit.ly/3VdxuNs
Join the webinar: bit.ly/3VdxuNs
September 10, 2025 at 12:27 PM
TODAY: Discover how Prof. Taekjip Ha (Harvard University) used the LUMICKS C-Trap to uncover real-time dynamics of chromatin remodelers and transcription factors at the single-molecule level.
Join the webinar: bit.ly/3VdxuNs
Join the webinar: bit.ly/3VdxuNs
CAR T cell therapy has revolutionized treatment for blood cancers, but why does it still not work on solid tumors?
Register for this upcoming webinar by Markus Barden (postdoc from Hinrich Abken's lab, Leibniz Institute for Immunotherapy) to learn more: bit.ly/464vLyZ
Register for this upcoming webinar by Markus Barden (postdoc from Hinrich Abken's lab, Leibniz Institute for Immunotherapy) to learn more: bit.ly/464vLyZ
September 5, 2025 at 3:59 PM
CAR T cell therapy has revolutionized treatment for blood cancers, but why does it still not work on solid tumors?
Register for this upcoming webinar by Markus Barden (postdoc from Hinrich Abken's lab, Leibniz Institute for Immunotherapy) to learn more: bit.ly/464vLyZ
Register for this upcoming webinar by Markus Barden (postdoc from Hinrich Abken's lab, Leibniz Institute for Immunotherapy) to learn more: bit.ly/464vLyZ
Looking back at a fantastic SMBio 2025 China at Hefei this past week 💪! Thank you USTC and Guoqiang Bi & Sai Li for hosting and co-organizing this memorable event for the single-molecule community.
September 2, 2025 at 2:05 PM
Looking back at a fantastic SMBio 2025 China at Hefei this past week 💪! Thank you USTC and Guoqiang Bi & Sai Li for hosting and co-organizing this memorable event for the single-molecule community.
𝗪𝗲’𝗿𝗲 𝗽𝗿𝗼𝘂𝗱 𝘁𝗼 𝘀𝘂𝗽𝗽𝗼𝗿𝘁 𝘁𝗵𝗲 𝗣𝗮𝗿𝗸𝗲𝗿 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲 𝗳𝗼𝗿 𝗖𝗮𝗻𝗰𝗲𝗿 𝗜𝗺𝗺𝘂𝗻𝗼𝘁𝗵𝗲𝗿𝗮𝗽𝘆 (𝗣𝗜𝗖𝗜) 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗶𝗻 𝘁𝗵𝗲 𝗳𝗶𝗴𝗵𝘁 𝗮𝗴𝗮𝗶𝗻𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿. @parkerici.bsky.social
August 8, 2025 at 8:41 AM
𝗪𝗲’𝗿𝗲 𝗽𝗿𝗼𝘂𝗱 𝘁𝗼 𝘀𝘂𝗽𝗽𝗼𝗿𝘁 𝘁𝗵𝗲 𝗣𝗮𝗿𝗸𝗲𝗿 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲 𝗳𝗼𝗿 𝗖𝗮𝗻𝗰𝗲𝗿 𝗜𝗺𝗺𝘂𝗻𝗼𝘁𝗵𝗲𝗿𝗮𝗽𝘆 (𝗣𝗜𝗖𝗜) 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗶𝗻 𝘁𝗵𝗲 𝗳𝗶𝗴𝗵𝘁 𝗮𝗴𝗮𝗶𝗻𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿. @parkerici.bsky.social
Speed up C-Trap user training, assay troubleshooting or performance verification 👉 try the new C-Trap Reference Kit.
The kit provides standardized and validated reagents for a complete DNA-protein binding assay, incl. data analysis with reference values.
Find the protocol & more: bit.ly/4mcXuUM
The kit provides standardized and validated reagents for a complete DNA-protein binding assay, incl. data analysis with reference values.
Find the protocol & more: bit.ly/4mcXuUM
July 23, 2025 at 1:38 PM
Speed up C-Trap user training, assay troubleshooting or performance verification 👉 try the new C-Trap Reference Kit.
The kit provides standardized and validated reagents for a complete DNA-protein binding assay, incl. data analysis with reference values.
Find the protocol & more: bit.ly/4mcXuUM
The kit provides standardized and validated reagents for a complete DNA-protein binding assay, incl. data analysis with reference values.
Find the protocol & more: bit.ly/4mcXuUM
The new DNA Repeat Assembly kit can deliver C-Trap users with the next increase in throughput, leading to statistically relevant results in a fraction of the time required.
👉 Find the DNA Repeat Assembly kit and the application note, including proof-of-concept data, in our store: bit.ly/3GSMBZ8
👉 Find the DNA Repeat Assembly kit and the application note, including proof-of-concept data, in our store: bit.ly/3GSMBZ8
July 21, 2025 at 2:41 PM
The new DNA Repeat Assembly kit can deliver C-Trap users with the next increase in throughput, leading to statistically relevant results in a fraction of the time required.
👉 Find the DNA Repeat Assembly kit and the application note, including proof-of-concept data, in our store: bit.ly/3GSMBZ8
👉 Find the DNA Repeat Assembly kit and the application note, including proof-of-concept data, in our store: bit.ly/3GSMBZ8
First, intermolecular ligation of the sequence of interest leads to the assembly of linear DNA constructs with multiple DNA repeats.
Second, a proprietary DNA adaptor containing 5 biotin moieties is added to the mix and the biotinylated adaptor ligates to the ends of the linear DNA constructs.
Second, a proprietary DNA adaptor containing 5 biotin moieties is added to the mix and the biotinylated adaptor ligates to the ends of the linear DNA constructs.
July 21, 2025 at 2:41 PM
First, intermolecular ligation of the sequence of interest leads to the assembly of linear DNA constructs with multiple DNA repeats.
Second, a proprietary DNA adaptor containing 5 biotin moieties is added to the mix and the biotinylated adaptor ligates to the ends of the linear DNA constructs.
Second, a proprietary DNA adaptor containing 5 biotin moieties is added to the mix and the biotinylated adaptor ligates to the ends of the linear DNA constructs.
Abstract deadline for the SMBio 2025 Nordics is approaching soon! Register with the link --> lumicks.com/event/symposium/smbio-nordics-2025
July 16, 2025 at 8:14 AM
Abstract deadline for the SMBio 2025 Nordics is approaching soon! Register with the link --> lumicks.com/event/symposium/smbio-nordics-2025
🧬 In a new study, researchers from Fernando Moreno ’s group observed KorB sliding to distant sites & stalling via KorA which directly visualizes the process of long-range repression.
This is the first time this regulatory mechanism has been visualized at the single-molecule level.
This is the first time this regulatory mechanism has been visualized at the single-molecule level.
July 14, 2025 at 1:30 PM
🧬 In a new study, researchers from Fernando Moreno ’s group observed KorB sliding to distant sites & stalling via KorA which directly visualizes the process of long-range repression.
This is the first time this regulatory mechanism has been visualized at the single-molecule level.
This is the first time this regulatory mechanism has been visualized at the single-molecule level.
There's a new double microfluidics module available for C-Trap users. What does it bring you?
👉 Having two independent microfluidics modules maximizes data acquisition time by enabling flow-cell cleaning in parallel with experimental execution. (1/3)
👉 Having two independent microfluidics modules maximizes data acquisition time by enabling flow-cell cleaning in parallel with experimental execution. (1/3)
July 8, 2025 at 12:35 PM
There's a new double microfluidics module available for C-Trap users. What does it bring you?
👉 Having two independent microfluidics modules maximizes data acquisition time by enabling flow-cell cleaning in parallel with experimental execution. (1/3)
👉 Having two independent microfluidics modules maximizes data acquisition time by enabling flow-cell cleaning in parallel with experimental execution. (1/3)
New for C-Trap users: the Accelerator Suite is here!
7 upgrades across hardware, software & kits to make your experiments faster, easier & more reproducible.
🎙️ Join our launch webinar to learn more + ask your questions live!
🔗 Register: www.lumicks.com/event/webina...
7 upgrades across hardware, software & kits to make your experiments faster, easier & more reproducible.
🎙️ Join our launch webinar to learn more + ask your questions live!
🔗 Register: www.lumicks.com/event/webina...
July 4, 2025 at 12:40 PM
New for C-Trap users: the Accelerator Suite is here!
7 upgrades across hardware, software & kits to make your experiments faster, easier & more reproducible.
🎙️ Join our launch webinar to learn more + ask your questions live!
🔗 Register: www.lumicks.com/event/webina...
7 upgrades across hardware, software & kits to make your experiments faster, easier & more reproducible.
🎙️ Join our launch webinar to learn more + ask your questions live!
🔗 Register: www.lumicks.com/event/webina...
🎆 SMBio is coming to Copenhagen! Join us for the 1st Nordics SMBio 2025 on Sept 4-5, focused on single-molecule research and optical manipulation of biological structures.
Connect, collaborate, and grow your network. Register by July 25 - spots are limited! Discover all here: bit.ly/4l3Sxgx
Connect, collaborate, and grow your network. Register by July 25 - spots are limited! Discover all here: bit.ly/4l3Sxgx
June 30, 2025 at 11:36 AM
🎆 SMBio is coming to Copenhagen! Join us for the 1st Nordics SMBio 2025 on Sept 4-5, focused on single-molecule research and optical manipulation of biological structures.
Connect, collaborate, and grow your network. Register by July 25 - spots are limited! Discover all here: bit.ly/4l3Sxgx
Connect, collaborate, and grow your network. Register by July 25 - spots are limited! Discover all here: bit.ly/4l3Sxgx
Coming Thursday: Dr. Alexander von Appen (MPI-CBG) will share groundbreaking research showing how a protein-DNA hydrogel forms a protective hydrogel at the nuclear envelope, visualized and tested by cryo-ET and optical tweezers. Join us this Thursday, June 26 at 4PM (GMT+2) for a deep dive!
June 23, 2025 at 9:50 AM
Coming Thursday: Dr. Alexander von Appen (MPI-CBG) will share groundbreaking research showing how a protein-DNA hydrogel forms a protective hydrogel at the nuclear envelope, visualized and tested by cryo-ET and optical tweezers. Join us this Thursday, June 26 at 4PM (GMT+2) for a deep dive!
How does the nuclear envelope protect the genome under stress?
Dr Alexander von Appen team saw that DNA + proteins form a co-condensate that reinforces the nucleus under force.
🧬 Join Dr Von Appen in the next webinar to learn how this hydrogel protects DNA!
📅 June 26 | 🕓 4PM
🔗 bit.ly/4dAJRLT
Dr Alexander von Appen team saw that DNA + proteins form a co-condensate that reinforces the nucleus under force.
🧬 Join Dr Von Appen in the next webinar to learn how this hydrogel protects DNA!
📅 June 26 | 🕓 4PM
🔗 bit.ly/4dAJRLT
June 3, 2025 at 12:16 PM
How does the nuclear envelope protect the genome under stress?
Dr Alexander von Appen team saw that DNA + proteins form a co-condensate that reinforces the nucleus under force.
🧬 Join Dr Von Appen in the next webinar to learn how this hydrogel protects DNA!
📅 June 26 | 🕓 4PM
🔗 bit.ly/4dAJRLT
Dr Alexander von Appen team saw that DNA + proteins form a co-condensate that reinforces the nucleus under force.
🧬 Join Dr Von Appen in the next webinar to learn how this hydrogel protects DNA!
📅 June 26 | 🕓 4PM
🔗 bit.ly/4dAJRLT
Better late then never: we hadn't yet send out a thank-you to the UK Bluesky single-molecule community, so here goes: THANKS to all who contributed to the UK SMBio 2025 -- we had a blast! 🙌🏼
Especially to @nynkedekkerlab.bsky.social & @achilleskap.bsky.social for co-organizing 🙏🏼!
Especially to @nynkedekkerlab.bsky.social & @achilleskap.bsky.social for co-organizing 🙏🏼!
May 29, 2025 at 11:15 AM
Better late then never: we hadn't yet send out a thank-you to the UK Bluesky single-molecule community, so here goes: THANKS to all who contributed to the UK SMBio 2025 -- we had a blast! 🙌🏼
Especially to @nynkedekkerlab.bsky.social & @achilleskap.bsky.social for co-organizing 🙏🏼!
Especially to @nynkedekkerlab.bsky.social & @achilleskap.bsky.social for co-organizing 🙏🏼!
New look, new website! You might have noticed already: over the past period we've been rolling out our content in a new style. Here's what our designers say:
May 28, 2025 at 7:41 AM
New look, new website! You might have noticed already: over the past period we've been rolling out our content in a new style. Here's what our designers say:
This weekend, our team, Trey Simpson and Hannah Stephens, are heading to Nashville for the FASEB Machine on Genes Conference (May 18–21)! We’re thrilled to support the single-molecule community and are especially delighted to sponsor a talk by our collaborator from Rockefeller, Yukun Wang.
May 16, 2025 at 4:05 PM
This weekend, our team, Trey Simpson and Hannah Stephens, are heading to Nashville for the FASEB Machine on Genes Conference (May 18–21)! We’re thrilled to support the single-molecule community and are especially delighted to sponsor a talk by our collaborator from Rockefeller, Yukun Wang.
The scientific community responded with fantastic curiosity to Avidion at AACR, and we couldn’t be more confident about the future of Cell Avidity in cell and antibody therapy. A great success!
(Still) curious? 👉 Discover more on the Avidion page: lumicks.com/avidion
(Still) curious? 👉 Discover more on the Avidion page: lumicks.com/avidion
May 7, 2025 at 1:08 PM
The scientific community responded with fantastic curiosity to Avidion at AACR, and we couldn’t be more confident about the future of Cell Avidity in cell and antibody therapy. A great success!
(Still) curious? 👉 Discover more on the Avidion page: lumicks.com/avidion
(Still) curious? 👉 Discover more on the Avidion page: lumicks.com/avidion
Are you a researcher in cancer immunotherapy?
A new study highlights potent biparatopic antibodies against FGFR fusion driven cancer. Join the Nature webinar to hear how the William Sellers lab is advancing biparatopic antibody therapies and tackling tumor resistance.
Register 👉: bit.ly/4csrfNt
A new study highlights potent biparatopic antibodies against FGFR fusion driven cancer. Join the Nature webinar to hear how the William Sellers lab is advancing biparatopic antibody therapies and tackling tumor resistance.
Register 👉: bit.ly/4csrfNt
April 29, 2025 at 2:46 PM
Are you a researcher in cancer immunotherapy?
A new study highlights potent biparatopic antibodies against FGFR fusion driven cancer. Join the Nature webinar to hear how the William Sellers lab is advancing biparatopic antibody therapies and tackling tumor resistance.
Register 👉: bit.ly/4csrfNt
A new study highlights potent biparatopic antibodies against FGFR fusion driven cancer. Join the Nature webinar to hear how the William Sellers lab is advancing biparatopic antibody therapies and tackling tumor resistance.
Register 👉: bit.ly/4csrfNt
Come by and say hi to the newest central member of our booth setup:
#Avidion - The next generation Cell Avidity platform!
📍 Join us at AACR booth #633.
The LUMICKS team is ready to meet you at the American Association for Cancer Research (AACR) Annual Meeting.
#Avidion - The next generation Cell Avidity platform!
📍 Join us at AACR booth #633.
The LUMICKS team is ready to meet you at the American Association for Cancer Research (AACR) Annual Meeting.
April 28, 2025 at 1:03 PM
Come by and say hi to the newest central member of our booth setup:
#Avidion - The next generation Cell Avidity platform!
📍 Join us at AACR booth #633.
The LUMICKS team is ready to meet you at the American Association for Cancer Research (AACR) Annual Meeting.
#Avidion - The next generation Cell Avidity platform!
📍 Join us at AACR booth #633.
The LUMICKS team is ready to meet you at the American Association for Cancer Research (AACR) Annual Meeting.