Lovasoa Randriantseheno
@lova14.bsky.social
PhD student studying the evolution of Yersinia pestis in Madagascar 🇲🇬 | Interested in all things bacteriology and genomics 👩🔬🧫🧬💻
Pinned
I had the great honor of representing Madagascar at the 15th International Symposium on Yersinia in Mongolia, where researchers working on the challenges posed by plague and other yersiniosis presented their work. I also presented some of the results of my PhD on the phylogeography of Y. pestis.
Reposted by Lovasoa Randriantseheno
A microbial horror show — an overview of some of the most devastating infectious diseases in history.
Dare to be scared, and be inspired by the stunning advances in the diagnosis, treatment and prevention of life-threatening infections.
Featuring cholera, measles and the plague, and many more.
Dare to be scared, and be inspired by the stunning advances in the diagnosis, treatment and prevention of life-threatening infections.
Featuring cholera, measles and the plague, and many more.
Pop-Up 2025 - Horror Show — Superbugs - The microbial world in, on and around us
www.superbugs.online
February 15, 2026 at 7:03 PM
A microbial horror show — an overview of some of the most devastating infectious diseases in history.
Dare to be scared, and be inspired by the stunning advances in the diagnosis, treatment and prevention of life-threatening infections.
Featuring cholera, measles and the plague, and many more.
Dare to be scared, and be inspired by the stunning advances in the diagnosis, treatment and prevention of life-threatening infections.
Featuring cholera, measles and the plague, and many more.
Reposted by Lovasoa Randriantseheno
We asked two microbiologists, Antonella Colque and Nurdana Orynbek, to test a selection of AI tools built for scientific publishing and research. The goal? To see how well these tools perform in real research tasks. Here is what worked for them.
And what did not : buff.ly/rm3775c
And what did not : buff.ly/rm3775c
February 8, 2026 at 7:00 AM
We asked two microbiologists, Antonella Colque and Nurdana Orynbek, to test a selection of AI tools built for scientific publishing and research. The goal? To see how well these tools perform in real research tasks. Here is what worked for them.
And what did not : buff.ly/rm3775c
And what did not : buff.ly/rm3775c
Reposted by Lovasoa Randriantseheno
WHO statement on notification of withdrawal of the United States
WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe.
Full statement: bit.ly/46dT0HF
WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe.
Full statement: bit.ly/46dT0HF
January 24, 2026 at 8:35 PM
WHO statement on notification of withdrawal of the United States
WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe.
Full statement: bit.ly/46dT0HF
WHO regrets the United States’ notification of withdrawal from WHO – a decision that makes both the United States and the world less safe.
Full statement: bit.ly/46dT0HF
Reposted by Lovasoa Randriantseheno
As Americans are hunkering down this weekend, congressional Republicans are stripping away the science that keeps us safe and prepared for future extreme weather.
NCAR isn't just a lab, it's the beating heart of US meteorology.
Write to your representative at tr.ee/save-ncar!
#saveNCAR #fundNCAR
NCAR isn't just a lab, it's the beating heart of US meteorology.
Write to your representative at tr.ee/save-ncar!
#saveNCAR #fundNCAR
January 23, 2026 at 3:03 PM
As Americans are hunkering down this weekend, congressional Republicans are stripping away the science that keeps us safe and prepared for future extreme weather.
NCAR isn't just a lab, it's the beating heart of US meteorology.
Write to your representative at tr.ee/save-ncar!
#saveNCAR #fundNCAR
NCAR isn't just a lab, it's the beating heart of US meteorology.
Write to your representative at tr.ee/save-ncar!
#saveNCAR #fundNCAR
Reposted by Lovasoa Randriantseheno
In @science.org, our Senior Adviser @drsethberkley.bsky.social pushes back on policies that weaken pandemic preparedness. Abandoning surveillance, vaccines, and proven public health tools puts Americans at risk, evidence-based strategies must lead policy.
More here ⬇️
www.science.org/doi/10.1126/...
More here ⬇️
www.science.org/doi/10.1126/...
Magical thinking will not prevent future pandemics or improve public health
For much of human history, infectious diseases were the main causes of morbidity and mortality. The sciences of public health, epidemiology, microbiology, and vaccine and drug development have dramati...
www.science.org
January 13, 2026 at 5:05 PM
In @science.org, our Senior Adviser @drsethberkley.bsky.social pushes back on policies that weaken pandemic preparedness. Abandoning surveillance, vaccines, and proven public health tools puts Americans at risk, evidence-based strategies must lead policy.
More here ⬇️
www.science.org/doi/10.1126/...
More here ⬇️
www.science.org/doi/10.1126/...
Reposted by Lovasoa Randriantseheno
🚨 New Epi Alert this week: No new Marburg cases in Ethiopia for 21 days & Nestlé recalls infant formula in 49 countries after B. cereus toxin detected. Updates on MERS-CoV in Saudia Arabia, dengue in Sri Lanka, India's waterborne disease epidemic & more. https://ow.ly/t5S350XpQJT
#IDSky #clinmicro
#IDSky #clinmicro
January 14, 2026 at 8:35 AM
🚨 New Epi Alert this week: No new Marburg cases in Ethiopia for 21 days & Nestlé recalls infant formula in 49 countries after B. cereus toxin detected. Updates on MERS-CoV in Saudia Arabia, dengue in Sri Lanka, India's waterborne disease epidemic & more. https://ow.ly/t5S350XpQJT
#IDSky #clinmicro
#IDSky #clinmicro
Reposted by Lovasoa Randriantseheno
A specific genetic difference in a gene called RTP5—known to be involved in smell and taste perception—was linked to a higher risk of early death in patients hospitalized with severe COVID-19, according to a recent study led by researchers at Harvard Chan School. @harvardenvhealth.bsky.social
Genetic difference may help explain wide variation in COVID severity | Harvard T.H. Chan School of Public Health
A specific genetic difference in a gene called RTP5—known to be involved in smell and taste perception—was linked to a higher risk of early death in patients hospitalized with severe COVID-19, a study...
hsph.harvard.edu
January 7, 2026 at 11:15 PM
A specific genetic difference in a gene called RTP5—known to be involved in smell and taste perception—was linked to a higher risk of early death in patients hospitalized with severe COVID-19, according to a recent study led by researchers at Harvard Chan School. @harvardenvhealth.bsky.social
Reposted by Lovasoa Randriantseheno
In the latest @who.int Medical Product Alert #falsified IBRANCE (palbociclib) – a drug used to treat certain breast cancers - has been detected in Cote d’Ivoire, Egypt, Lebanon, Libya and Turkey #FakeMeds
Read more www.who.int/news/item/15...
Read more www.who.int/news/item/15...
Medical Product Alert N°7/2025: Falsified IBRANCE (palbociclib)
Alert SummaryThis WHO Medical Product Alert refers to nine lots of falsified IBRANCE (palbociclib). These falsified products have been detected in Cote d’Ivoire, Egypt, Lebanon, Libya and Türkiye and…
www.who.int
December 22, 2025 at 11:30 AM
In the latest @who.int Medical Product Alert #falsified IBRANCE (palbociclib) – a drug used to treat certain breast cancers - has been detected in Cote d’Ivoire, Egypt, Lebanon, Libya and Turkey #FakeMeds
Read more www.who.int/news/item/15...
Read more www.who.int/news/item/15...
Reposted by Lovasoa Randriantseheno
Early-stage cancer classified with 100% sensitivity, using cell-free RNA. Read how researchers detected cancer early using Oxford Nanopore sequencing as a non-invasive tool, with the potential to inform cancer care more rapidly and accurately than before. https://bit.ly/4rqvHDH
December 22, 2025 at 3:48 PM
Early-stage cancer classified with 100% sensitivity, using cell-free RNA. Read how researchers detected cancer early using Oxford Nanopore sequencing as a non-invasive tool, with the potential to inform cancer care more rapidly and accurately than before. https://bit.ly/4rqvHDH
Reposted by Lovasoa Randriantseheno
New WHO report shows growing resistance to lifesaving malaria drugs:
🚩 Partial resistance to artemisinin confirmed or suspected in at least 8 African countries
🚩 Pyrethroid resistance in 48 countries
🚩 Anopheles stephensi 🦟 now detected in 9 African countries
🔗 bit.ly/3Y6IcXn #EndMalaria
🚩 Partial resistance to artemisinin confirmed or suspected in at least 8 African countries
🚩 Pyrethroid resistance in 48 countries
🚩 Anopheles stephensi 🦟 now detected in 9 African countries
🔗 bit.ly/3Y6IcXn #EndMalaria
December 5, 2025 at 7:45 AM
New WHO report shows growing resistance to lifesaving malaria drugs:
🚩 Partial resistance to artemisinin confirmed or suspected in at least 8 African countries
🚩 Pyrethroid resistance in 48 countries
🚩 Anopheles stephensi 🦟 now detected in 9 African countries
🔗 bit.ly/3Y6IcXn #EndMalaria
🚩 Partial resistance to artemisinin confirmed or suspected in at least 8 African countries
🚩 Pyrethroid resistance in 48 countries
🚩 Anopheles stephensi 🦟 now detected in 9 African countries
🔗 bit.ly/3Y6IcXn #EndMalaria
Reposted by Lovasoa Randriantseheno
www.biorxiv.org/content/10.1...
@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage
@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage
Bacteria sense virus-induced genome degradation via methylated mononucleotides
Phages often degrade the genome of their bacterial host to individual nucleotides and use these nucleotides to build their own genome. In this study, we describe a bacterial defense system that direct...
www.biorxiv.org
November 8, 2025 at 5:22 PM
www.biorxiv.org/content/10.1...
@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage
@soreklab.bsky.social Sorek lab does it again! Such a cool signal to specifically detect the event of genome degradation by a phage
Reposted by Lovasoa Randriantseheno
💚 Last night, the Institut Pasteur lit up its historic building in green: the color of Phelan‑McDermid syndrome.
This rare genetic disorder is linked to developmental & language challenges and autism.
It was here that researchers identified SHANK3, the gene behind the syndrome 🧬✨
This rare genetic disorder is linked to developmental & language challenges and autism.
It was here that researchers identified SHANK3, the gene behind the syndrome 🧬✨
October 23, 2025 at 1:43 PM
💚 Last night, the Institut Pasteur lit up its historic building in green: the color of Phelan‑McDermid syndrome.
This rare genetic disorder is linked to developmental & language challenges and autism.
It was here that researchers identified SHANK3, the gene behind the syndrome 🧬✨
This rare genetic disorder is linked to developmental & language challenges and autism.
It was here that researchers identified SHANK3, the gene behind the syndrome 🧬✨
Reposted by Lovasoa Randriantseheno
Across Southeast Asia most newborn infections are now caused #AMR bugs, making standard treatments for neonatal sepsis ineffective. Without updated, locally informed treatment guidelines and new antibiotic development, infant mortality rates will rise.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Pathogen distribution and antimicrobial resistance among neonatal bloodstream infections in Southeast Asia: results from NeoSEAP, a multicentre retrospective study
Neonatal sepsis in tertiary hospitals in Southeast Asia is predominantly caused by
gram-negative bacteria, with high rates of non-susceptibility to commonly prescribed
antibiotics.
www.thelancet.com
October 12, 2025 at 11:29 AM
Across Southeast Asia most newborn infections are now caused #AMR bugs, making standard treatments for neonatal sepsis ineffective. Without updated, locally informed treatment guidelines and new antibiotic development, infant mortality rates will rise.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Lovasoa Randriantseheno
This is amazing! Researchers at McMaster University have discovered an antibiotic that could treat inflammatory bowel diseases, including Crohn’s Disease without killing beneficial gut bacteria
healthsci.mcmaster.ca/new-antibiot...
healthsci.mcmaster.ca/new-antibiot...
healthsci.mcmaster.ca
October 4, 2025 at 1:06 PM
This is amazing! Researchers at McMaster University have discovered an antibiotic that could treat inflammatory bowel diseases, including Crohn’s Disease without killing beneficial gut bacteria
healthsci.mcmaster.ca/new-antibiot...
healthsci.mcmaster.ca/new-antibiot...
I had the great honor of representing Madagascar at the 15th International Symposium on Yersinia in Mongolia, where researchers working on the challenges posed by plague and other yersiniosis presented their work. I also presented some of the results of my PhD on the phylogeography of Y. pestis.
September 22, 2025 at 5:27 AM
I had the great honor of representing Madagascar at the 15th International Symposium on Yersinia in Mongolia, where researchers working on the challenges posed by plague and other yersiniosis presented their work. I also presented some of the results of my PhD on the phylogeography of Y. pestis.
Reposted by Lovasoa Randriantseheno
💊 New antibiotic class
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Novltex: A New Class of Antibiotics with Potent Activity against Multidrug-Resistant Bacterial Pathogens─Design, Synthesis, and Biological Evaluation
Increasing spread of multidrug-resistant (MDR) bacteria demands antibiotics that combine potent activity with scalable synthesis. Novo29 (clovibactin) is promising but suffers from low yield (1%), dep...
pubs.acs.org
September 20, 2025 at 6:21 PM
💊 New antibiotic class
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Reposted by Lovasoa Randriantseheno
A new model sheds light on the seasonal dynamics of plague in Madagascar — a step toward better prevention through a One Health approach.
🔗 Read more: www.pasteur.fr/en/research-...
@scauchemez.bsky.social
@abrault.bsky.social
@fanohi.bsky.social
🔗 Read more: www.pasteur.fr/en/research-...
@scauchemez.bsky.social
@abrault.bsky.social
@fanohi.bsky.social
Plague in Madagascar: a new model sheds light on the seasonality of outbreaks
A new model has been developed to elucidate the seasonal dynamics of plague in Madagascar. In this country, where the disease remains endemic, and most often occurs between October and March. The asso...
www.pasteur.fr
September 12, 2025 at 9:32 AM
A new model sheds light on the seasonal dynamics of plague in Madagascar — a step toward better prevention through a One Health approach.
🔗 Read more: www.pasteur.fr/en/research-...
@scauchemez.bsky.social
@abrault.bsky.social
@fanohi.bsky.social
🔗 Read more: www.pasteur.fr/en/research-...
@scauchemez.bsky.social
@abrault.bsky.social
@fanohi.bsky.social
Reposted by Lovasoa Randriantseheno
🌡️ Heat is already hurting billions.
Outdoor & manual workers in agriculture, construction & beyond face rising temperatures that slash productivity & threaten lives.
The new WHO / @wmo-global.bsky.social report shares practical, evidence-based solutions 👉 bit.ly/3JvqKI1 #ClimateAction
Outdoor & manual workers in agriculture, construction & beyond face rising temperatures that slash productivity & threaten lives.
The new WHO / @wmo-global.bsky.social report shares practical, evidence-based solutions 👉 bit.ly/3JvqKI1 #ClimateAction
August 22, 2025 at 6:44 AM
🌡️ Heat is already hurting billions.
Outdoor & manual workers in agriculture, construction & beyond face rising temperatures that slash productivity & threaten lives.
The new WHO / @wmo-global.bsky.social report shares practical, evidence-based solutions 👉 bit.ly/3JvqKI1 #ClimateAction
Outdoor & manual workers in agriculture, construction & beyond face rising temperatures that slash productivity & threaten lives.
The new WHO / @wmo-global.bsky.social report shares practical, evidence-based solutions 👉 bit.ly/3JvqKI1 #ClimateAction
Plague is not a disease of the past
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
California resident tests positive for the plague after camping, officials say
South Lake Tahoe resident was probably bitten by infected flea while camping in the area, local health authorities say
www.theguardian.com
August 22, 2025 at 1:52 AM
Plague is not a disease of the past
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
Reposted by Lovasoa Randriantseheno
An exciting negative result!
At the same time, we made thousands of synonymous mutations in endogenous yeast genes and measured their growth. We used careful statistics and controls. Only 3%, 204 of 6874, had a fitness effect! This goes against a controversial recent result that most synonymous mutations had fitness effects.
August 8, 2025 at 9:23 PM
An exciting negative result!
Reposted by Lovasoa Randriantseheno
“In a paper published in Nature Communications, the researchers have shown for the 1st time that mRNA can be delivered into the cells where HIV is hiding, by encasing it in a tiny, specially formulated fat bubble. The mRNA then instructs the cells to reveal the virus.”
The virus can no longer hide!
The virus can no longer hide!
June 5, 2025 at 9:12 AM
“In a paper published in Nature Communications, the researchers have shown for the 1st time that mRNA can be delivered into the cells where HIV is hiding, by encasing it in a tiny, specially formulated fat bubble. The mRNA then instructs the cells to reveal the virus.”
The virus can no longer hide!
The virus can no longer hide!
Reposted by Lovasoa Randriantseheno
New research from LSTM shows E. coli can evolve drug resistance mid-treatment by amplifying an existing gene, not gaining a new one.
A striking reminder of how quickly resistance can emerge.
🔗
A striking reminder of how quickly resistance can emerge.
🔗
New study shows that E. coli can evolve antibiotic resistance during treatment
This new study, led by Liverpool School of Tropical Medicine (LSTM) and published in the Journal of Medical Microbiology, details the rapid evolution of resistance in an E.
lstm.ac
August 5, 2025 at 2:28 PM
New research from LSTM shows E. coli can evolve drug resistance mid-treatment by amplifying an existing gene, not gaining a new one.
A striking reminder of how quickly resistance can emerge.
🔗
A striking reminder of how quickly resistance can emerge.
🔗
Reposted by Lovasoa Randriantseheno
In our latest blog post, our Data Scientist Osheen MacOscar shares a great overview of how to use {ggplot2} and {gganimate}, when dealing with spatial data.
#rstats #datavis #spatialdata #maps
#rstats #datavis #spatialdata #maps
Animated Maps with {ggplot2} and {gganimate}
In this blog we are creating an animated map of the gapminder data using {ggplot2} and {gganimate}. In the process we will cover some of the common pitfalls when working with spatial data and how to get round them!
www.jumpingrivers.com
July 31, 2025 at 10:41 AM
In our latest blog post, our Data Scientist Osheen MacOscar shares a great overview of how to use {ggplot2} and {gganimate}, when dealing with spatial data.
#rstats #datavis #spatialdata #maps
#rstats #datavis #spatialdata #maps
Reposted by Lovasoa Randriantseheno
Telomere-to-telomere assembly detects genomic diversity in Canadian strains of Borrelia burgdorferi
diversity & conservation among Lyme spirochetes, including the curious DNA chunk that is sometimes on the chromosome, other times a separate linear plasmid
#MicroSky
www.biorxiv.org/content/10.1...
diversity & conservation among Lyme spirochetes, including the curious DNA chunk that is sometimes on the chromosome, other times a separate linear plasmid
#MicroSky
www.biorxiv.org/content/10.1...
July 31, 2025 at 3:16 PM
Telomere-to-telomere assembly detects genomic diversity in Canadian strains of Borrelia burgdorferi
diversity & conservation among Lyme spirochetes, including the curious DNA chunk that is sometimes on the chromosome, other times a separate linear plasmid
#MicroSky
www.biorxiv.org/content/10.1...
diversity & conservation among Lyme spirochetes, including the curious DNA chunk that is sometimes on the chromosome, other times a separate linear plasmid
#MicroSky
www.biorxiv.org/content/10.1...
Reposted by Lovasoa Randriantseheno
New pre-print from my lab!
Plasmids link antibiotic resistance and phage defense.
E.coli plasmids are hotspots for both antibiotic resistance and phage defense. Phage therapy has the potential to accidentally select for antibiotic resistance!!!
#microsky#AMR#phage
www.biorxiv.org/content/10.1....
Plasmids link antibiotic resistance and phage defense.
E.coli plasmids are hotspots for both antibiotic resistance and phage defense. Phage therapy has the potential to accidentally select for antibiotic resistance!!!
#microsky#AMR#phage
www.biorxiv.org/content/10.1....
Plasmids link antibiotic resistance genes and phage defense systems in E. coli
Phage therapy has been proposed as an alternative to antibiotics to treat resistant infections. However, we have a limited understanding of how antibiotic resistance genes (ARGs) associate with bacter...
www.biorxiv.org
July 29, 2025 at 1:28 PM
New pre-print from my lab!
Plasmids link antibiotic resistance and phage defense.
E.coli plasmids are hotspots for both antibiotic resistance and phage defense. Phage therapy has the potential to accidentally select for antibiotic resistance!!!
#microsky#AMR#phage
www.biorxiv.org/content/10.1....
Plasmids link antibiotic resistance and phage defense.
E.coli plasmids are hotspots for both antibiotic resistance and phage defense. Phage therapy has the potential to accidentally select for antibiotic resistance!!!
#microsky#AMR#phage
www.biorxiv.org/content/10.1....