Florens Lohrmann
@lohrmanf.bsky.social
Neonatologist & scientist @Karolinska Institute | Exploring neonatal immune development and innate immunity | Advocate for child health, science, and sustainability.
Reposted by Florens Lohrmann
Online now: Sensory neurons shape local macrophage identity via TGF-β signaling
Sensory neurons shape local macrophage identity via TGF-β signaling
Specialized macrophages are known to persist within tissue niches, but the molecular mechanisms guiding their sustained functional adaptation remain unclear. Kolter and Döring et al. show that local interactions between sensory nerves and macrophages activate TGF-β, which imprints and maintains nerve-associated macrophages that contribute to regeneration after tissue injury.
dlvr.it
September 5, 2025 at 2:48 PM
Online now: Sensory neurons shape local macrophage identity via TGF-β signaling
Excited to share our new paper on pediatric non-tuberculous mycobacterial (NTM) lymphadenitis. Using advanced histology we identify patterns associated with favorable outcomes. We hope this helps refine NTM care.
Open access @Frontiers in Immunology:
www.frontiersin.org/journals/imm...
Open access @Frontiers in Immunology:
www.frontiersin.org/journals/imm...
Frontiers | Immunopathogenic and clinical implications of advanced tissue analysis in non-tuberculous mycobacterial infections in children
ObjectivesInfections with non-tuberculous mycobacteria (NTM) in children usually affect the lymph nodes and surrounding tissue. Although the infection is typ...
www.frontiersin.org
September 10, 2025 at 3:23 PM
Excited to share our new paper on pediatric non-tuberculous mycobacterial (NTM) lymphadenitis. Using advanced histology we identify patterns associated with favorable outcomes. We hope this helps refine NTM care.
Open access @Frontiers in Immunology:
www.frontiersin.org/journals/imm...
Open access @Frontiers in Immunology:
www.frontiersin.org/journals/imm...
Follow-up study: After our recent paper on PIMS-TS/MIS-C across pandemic waves, we’re now reporting on intermediate-term outcomes. Read the paper @Journal of Pediatrics:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Recovery from Pediatric Inflammatory Multisystem Syndrome Temporally-Associated with SARS-CoV-2: Follow-Up from a Nationwide German Cohort
To investigate the intermediate-term health impacts of pediatric inflammatory multisystem syndrome temporally-associated with SARS-CoV-2 (PIMS-TS).Usi…
www.sciencedirect.com
September 10, 2025 at 3:16 PM
Follow-up study: After our recent paper on PIMS-TS/MIS-C across pandemic waves, we’re now reporting on intermediate-term outcomes. Read the paper @Journal of Pediatrics:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Florens Lohrmann
Mycobacterial infection uncovers plasticity of Kupffer cells https://www.biorxiv.org/content/10.1101/2025.02.07.636999v1
February 9, 2025 at 5:19 AM
Mycobacterial infection uncovers plasticity of Kupffer cells https://www.biorxiv.org/content/10.1101/2025.02.07.636999v1
Reposted by Florens Lohrmann
Sensory neurons shape macrophage identity via TGF-β signalling https://www.biorxiv.org/content/10.1101/2025.02.06.635770v1
February 8, 2025 at 8:16 AM
Sensory neurons shape macrophage identity via TGF-β signalling https://www.biorxiv.org/content/10.1101/2025.02.06.635770v1
Excited to announce a new preprint from the Henneke Lab:
"Tissue imprinting defines functional mosaic of dermal macrophages"
It explores how dermal macrophages adapt and specialize within their microenvironment during infections. Feedback and discussions welcome!
www.biorxiv.org/content/10.1...
"Tissue imprinting defines functional mosaic of dermal macrophages"
It explores how dermal macrophages adapt and specialize within their microenvironment during infections. Feedback and discussions welcome!
www.biorxiv.org/content/10.1...
Tissue imprinting defines functional mosaic of dermal macrophages
Dermal macrophages (macs) protect the skin from invading pathogens. They are derived from embryonic as well as hematopoietic progenitors. However, the functional impact of their diverse origin and the...
www.biorxiv.org
January 13, 2025 at 7:53 PM
Excited to announce a new preprint from the Henneke Lab:
"Tissue imprinting defines functional mosaic of dermal macrophages"
It explores how dermal macrophages adapt and specialize within their microenvironment during infections. Feedback and discussions welcome!
www.biorxiv.org/content/10.1...
"Tissue imprinting defines functional mosaic of dermal macrophages"
It explores how dermal macrophages adapt and specialize within their microenvironment during infections. Feedback and discussions welcome!
www.biorxiv.org/content/10.1...
Join the cutting-edge discussions at the International Symposium on Perinatal and Early Life Immunity, April 9-12 2025, Freiburg, Germany.
www.perinatal-immunity.de/en/symposium2025
Late-breaking abstracts still accepted!
www.perinatal-immunity.de/en/symposium2025
Late-breaking abstracts still accepted!
January 9, 2025 at 9:17 AM
Join the cutting-edge discussions at the International Symposium on Perinatal and Early Life Immunity, April 9-12 2025, Freiburg, Germany.
www.perinatal-immunity.de/en/symposium2025
Late-breaking abstracts still accepted!
www.perinatal-immunity.de/en/symposium2025
Late-breaking abstracts still accepted!
In press @Journal of Pediatrics
Clinical insights from the German PIMS-TS cohort: A comprehensive analysis of an all-but-extinct pediatric inflammatory disease.
www.jpeds.com/article/S002...
Clinical insights from the German PIMS-TS cohort: A comprehensive analysis of an all-but-extinct pediatric inflammatory disease.
www.jpeds.com/article/S002...
DEFINE_ME
www.jpeds.com
November 26, 2024 at 11:34 AM
In press @Journal of Pediatrics
Clinical insights from the German PIMS-TS cohort: A comprehensive analysis of an all-but-extinct pediatric inflammatory disease.
www.jpeds.com/article/S002...
Clinical insights from the German PIMS-TS cohort: A comprehensive analysis of an all-but-extinct pediatric inflammatory disease.
www.jpeds.com/article/S002...