Li Zhao
lizhao.bsky.social
Li Zhao
@lizhao.bsky.social
Associate Professor at the Rockefeller University. We study gene origination, molecular evolution, and the genetic basis of adaptive traits.
Wow. You truly transformed the house into a great one. How did you mange to have a garden and make sure deers don't eat everything?
September 8, 2025 at 4:18 PM
as one would wonder if it's the tMAC effect or Achi/Vis effect. For the transgenic+RNAseq analysis we see 5 genes (aly, come, tomb, p55 and wuc) showed positive exp. correlations with vis expression, whereas topi and mip40 did not. The 5 genes may play a partial role although we are not sure yet.
July 16, 2025 at 5:42 PM
Thanks for the kind words, Jongmin. This work was the work I briefly mentioned in the Q&A (but not the talk) related to your question in my seminar visit at Cornell last fall. We checked the tMAC complex and the pattern observed by large-scale computation is specific to Achi/Vis... ( next thread)
July 16, 2025 at 5:42 PM
Thank you for your kind words. Look forward to seeing more of your work in this subfield too.
July 16, 2025 at 5:34 PM
Here is the Rockefeller press release: www.rockefeller.edu/news/38025-h.... Thank you for promoting our science.
How new genes get switched on - News
Scientists discovered an identical neural circuit that operates differently in male and female mice.
www.rockefeller.edu
July 15, 2025 at 2:27 PM
4) he provided evidence supporting the cultivator model of de novo gene origination, a model he proposed to explore the link between novel genes/lncRNAs and nearby functionally important genes academic.oup.com/gbe/article/...
A Synergistic, Cultivator Model of De Novo Gene Origination
Abstract. The origin and fixation of evolutionarily young genes is a fundamental question in evolutionary biology. However, understanding the origins of ne
academic.oup.com
May 8, 2025 at 7:46 PM
2) he used single cell cluster and RNA FISH to confirm that many important "maker genes" show rapid changes of gene expression among specie, 3) he also find some interesting patterns of transcriptional busting size/frequency in spermatogenesis,
May 8, 2025 at 7:46 PM
Such a simple and efficient way to make a small quantity of specific fly food media👍
February 6, 2025 at 5:50 PM