Lino Ferreira
@linoafferreira.bsky.social
Researcher in statistical genetics
PhD from Oxford
lfe.pt
PhD from Oxford
lfe.pt
Reposted by Lino Ferreira
New study in #GENETICS from @anaignatieva.bsky.social and @linoafferreira.bsky.social shows how ancestral recombination graphs can help detect "phantom" genetic interaction signals that arise due to genealogy and not because of epistasis. buff.ly/TQARoDp
October 16, 2025 at 1:04 PM
New study in #GENETICS from @anaignatieva.bsky.social and @linoafferreira.bsky.social shows how ancestral recombination graphs can help detect "phantom" genetic interaction signals that arise due to genealogy and not because of epistasis. buff.ly/TQARoDp
Reposted by Lino Ferreira
Our paper about how ancestral recombination graphs can be used to detect "phantom" genetic interaction signals (that arise due to the genealogy, rather than "real" epistasis) is out in Genetics! Nice thread here by @linoafferreira.bsky.social
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
September 15, 2025 at 10:33 AM
Our paper about how ancestral recombination graphs can be used to detect "phantom" genetic interaction signals (that arise due to the genealogy, rather than "real" epistasis) is out in Genetics! Nice thread here by @linoafferreira.bsky.social
academic.oup.com/genetics/adv...
academic.oup.com/genetics/adv...
Delighted to see this paper with @anaignatieva.bsky.social now published in Genetics!
academic.oup.com/genetics/adv...
We tackle a thorny issue arising in statistical tests for genetic interactions (epistasis) using ancestral recombination graphs (ARGs)... 🧵
academic.oup.com/genetics/adv...
We tackle a thorny issue arising in statistical tests for genetic interactions (epistasis) using ancestral recombination graphs (ARGs)... 🧵
Phantom epistasis through the lens of genealogies
Abstract. Phantom epistasis arises when, in the course of testing for gene-by-gene interactions, the omission of a causal variant with a purely additive ef
academic.oup.com
September 10, 2025 at 4:31 PM
Delighted to see this paper with @anaignatieva.bsky.social now published in Genetics!
academic.oup.com/genetics/adv...
We tackle a thorny issue arising in statistical tests for genetic interactions (epistasis) using ancestral recombination graphs (ARGs)... 🧵
academic.oup.com/genetics/adv...
We tackle a thorny issue arising in statistical tests for genetic interactions (epistasis) using ancestral recombination graphs (ARGs)... 🧵
Excited to have this out there! Comments are very welcome.
New preprint (with @linoafferreira.bsky.social) where we explore the idea of using genealogies (in the form of ancestral recombination graphs, ARGs) to tell apart real GxG interaction signals between nearby variants from false positives www.biorxiv.org/content/10.1...
Phantom epistasis through the lens of genealogies
Phantom epistasis arises when, in the course of testing for gene-by-gene interactions, the omission of a causal variant (with a purely additive effect on the phenotype) causes the spurious inference o...
www.biorxiv.org
December 9, 2024 at 7:03 PM
Excited to have this out there! Comments are very welcome.
Reposted by Lino Ferreira
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
November 25, 2024 at 11:19 AM
📣 Two ERC-funded positions are available in the lab! If you are interested in exploring the mechanisms underlying mutation, we’d love to hear from you.
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
PhD: shorturl.at/Oc04N
Postdoc: shorturl.at/1ShHB
RPs and shares would be greatly appreciated!
🧪🧬🖥️ #ScienceJobs #PostdocJobs
Reposted by Lino Ferreira
The Hinch lab is looking for an enthusiastic statistician, mathematician or physicist to join us as a post doc!
If you'd like to use big data to decode the inner workings of our cells, apply now: germlinegenomics.web.ox.ac.uk
Please re-post and thanks!
#PhDjobs #Postdocs #STEM #meiosis #genomics
If you'd like to use big data to decode the inner workings of our cells, apply now: germlinegenomics.web.ox.ac.uk
Please re-post and thanks!
#PhDjobs #Postdocs #STEM #meiosis #genomics
June 11, 2024 at 11:31 AM
Reposted by Lino Ferreira
Congratulations to Carl Veller on the publication of his article on confounding in population and family GWAS
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Interpreting population- and family-based genome-wide association studies in the presence of confounding
GWASs aim to estimate direct effects of genotype on an individual’s phenotype, but this can be subject to genetic and environmental confounds and
journals.plos.org
April 12, 2024 at 4:28 AM
Congratulations to Carl Veller on the publication of his article on confounding in population and family GWAS
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
My PhD programme, the 'DPhil in Genomic Medicine and Statistics' at the Wellcome Centre for Human Genetics in Oxford, is accepting applications for next year!
I'm coming to the end of my studies after four years and feel so fortunate to have been part of it. Students get...
I'm coming to the end of my studies after four years and feel so fortunate to have been part of it. Students get...
October 18, 2023 at 1:42 PM
My PhD programme, the 'DPhil in Genomic Medicine and Statistics' at the Wellcome Centre for Human Genetics in Oxford, is accepting applications for next year!
I'm coming to the end of my studies after four years and feel so fortunate to have been part of it. Students get...
I'm coming to the end of my studies after four years and feel so fortunate to have been part of it. Students get...
First post on this celestial platform to mark a happy occasion: I've submitted my PhD thesis!
I've celebrated and rested well and am now back to working on research after all the writing... Excited for what's to come!
I've celebrated and rested well and am now back to working on research after all the writing... Excited for what's to come!
October 18, 2023 at 1:39 PM
First post on this celestial platform to mark a happy occasion: I've submitted my PhD thesis!
I've celebrated and rested well and am now back to working on research after all the writing... Excited for what's to come!
I've celebrated and rested well and am now back to working on research after all the writing... Excited for what's to come!