Shane Liddelow
@liddelowsa.bsky.social
Neuroscientist and glial aficionado at NYU Grossman School of Medicine/NYU Langone Health in NYC. Posts in my individual/personal capacity.
My lab is full of awesome people doing amazing stuff - check them out: www.liddelowlab.com
he/him
My lab is full of awesome people doing amazing stuff - check them out: www.liddelowlab.com
he/him
#SfN #SocietyForGlia #Astrocytes
ENDING STRONG in Astrocyte land here in San Diego.
Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions.
See you in 2026!
ENDING STRONG in Astrocyte land here in San Diego.
Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions.
See you in 2026!
November 19, 2025 at 5:39 PM
#SfN #SocietyForGlia #Astrocytes
ENDING STRONG in Astrocyte land here in San Diego.
Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions.
See you in 2026!
ENDING STRONG in Astrocyte land here in San Diego.
Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions.
See you in 2026!
November 19, 2025 at 1:42 PM
#SfN #SocietyForGlia
STARTING NOW!
Ending strong with the last www.liddelowlab.com presentations of the week.
@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!
@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
STARTING NOW!
Ending strong with the last www.liddelowlab.com presentations of the week.
@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!
@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
November 18, 2025 at 8:58 PM
#SfN #SocietyForGlia
STARTING NOW!
Ending strong with the last www.liddelowlab.com presentations of the week.
@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!
@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
STARTING NOW!
Ending strong with the last www.liddelowlab.com presentations of the week.
@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!
@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
#SfN25 #SocietyForGlia #Astrocytes
IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time!
as always, apologies to those I have missed - please comment below with more sessions and presentations!
IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time!
as always, apologies to those I have missed - please comment below with more sessions and presentations!
November 18, 2025 at 4:02 PM
#SfN25 #SocietyForGlia #Astrocytes
IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time!
as always, apologies to those I have missed - please comment below with more sessions and presentations!
IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time!
as always, apologies to those I have missed - please comment below with more sessions and presentations!
IT'S A BUSY AFTERNOON FOR THE LAB!
@mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain
Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?)
@liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
@mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain
Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?)
@liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
November 17, 2025 at 8:39 PM
IT'S A BUSY AFTERNOON FOR THE LAB!
@mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain
Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?)
@liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
@mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain
Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?)
@liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
November 17, 2025 at 4:11 PM
#SfN25 #SocietyForGlia #Astrocytes
Monday is a BUSY day - see you all out there!
(apologies for anyone's presentation I missed - please comment below with details)
Monday is a BUSY day - see you all out there!
(apologies for anyone's presentation I missed - please comment below with details)
November 17, 2025 at 2:44 PM
#SfN25 #SocietyForGlia #Astrocytes
Monday is a BUSY day - see you all out there!
(apologies for anyone's presentation I missed - please comment below with details)
Monday is a BUSY day - see you all out there!
(apologies for anyone's presentation I missed - please comment below with details)
#SocietyForGlia #SfN25 #Astrocytes
Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see.
Apologies again for anyone I missed - please link your presentations below
Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see.
Apologies again for anyone I missed - please link your presentations below
November 16, 2025 at 3:32 PM
#SocietyForGlia #SfN25 #Astrocytes
Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see.
Apologies again for anyone I missed - please link your presentations below
Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see.
Apologies again for anyone I missed - please link your presentations below
#SocietyForGlia #SfN25 #Astrocytes
Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!
See you about the conference
Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!
See you about the conference
November 15, 2025 at 8:35 PM
#SocietyForGlia #SfN25 #Astrocytes
Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!
See you about the conference
Astrocyte presentation round up for Day 1.
Sorry if I missed anyone, please comment below with others!
See you about the conference
#SfN25 #SocietyForGlia #Astrocytes
@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
November 15, 2025 at 8:33 PM
#SfN25 #SocietyForGlia #Astrocytes
@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
@borderbiologist.bsky.social presenting now!
Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
Reposted by Shane Liddelow
Very happy to have contributed to this new review on Lewy body dementia in @thelancetneuro.bsky.social led by Sonja W. Scholz. We highlight the latest advances in genetics and pathology. @liddelowsa.bsky.social Check it out! www.sciencedirect.com/science/arti...
Advances in the genetics and pathology of Lewy body dementia
Lewy body dementia is a heterogeneous disease that is underdiagnosed and poorly understood. Pathologically, Lewy body dementia is characterised by the…
www.sciencedirect.com
November 13, 2025 at 12:56 AM
Very happy to have contributed to this new review on Lewy body dementia in @thelancetneuro.bsky.social led by Sonja W. Scholz. We highlight the latest advances in genetics and pathology. @liddelowsa.bsky.social Check it out! www.sciencedirect.com/science/arti...
Reposted by Shane Liddelow
In case you were wondering what to do with precisely 150 minutes of your existence @sfn.org #SfN25 #SanDiego. Join our mini-symposium Single-Cell Multiomics in CNS Injury and Recovery. Guaranteed to contain many glial cells and at least a neuron. I am Co-chairing with Naomi Habib
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
November 11, 2025 at 5:14 PM
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
November 10, 2025 at 4:43 PM
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Reposted by Shane Liddelow
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
October 29, 2025 at 2:57 PM
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Date: Monday, Nov 17th
Time: 9PM till close
Location: The Smoking Gun SD, 555 Market St.
All welcome, please free to spread the word!
Reposted by Shane Liddelow
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
www.nature.com
November 5, 2025 at 4:03 PM
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Shane Liddelow
Oligodendrocytes support functional development of subcortical premotor neurons and navigation https://www.biorxiv.org/content/10.1101/2025.11.01.686017v1
November 2, 2025 at 10:15 AM
Oligodendrocytes support functional development of subcortical premotor neurons and navigation https://www.biorxiv.org/content/10.1101/2025.11.01.686017v1
We've been doing some amazing stuff outside the astrocyte realm.
Check out our latest Oligo investigation led by @pryprk.bsky.social !
Check out our latest Oligo investigation led by @pryprk.bsky.social !
I am proud to share our work on X-linked Dystonia-Parkinsonism — a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene.
Read our two companion papers:
🔹 www.biorxiv.org/content/10.1...
🔹 www.biorxiv.org/content/10.1...
🧵 Highlights below!
Read our two companion papers:
🔹 www.biorxiv.org/content/10.1...
🔹 www.biorxiv.org/content/10.1...
🧵 Highlights below!
October 24, 2025 at 4:40 PM
We've been doing some amazing stuff outside the astrocyte realm.
Check out our latest Oligo investigation led by @pryprk.bsky.social !
Check out our latest Oligo investigation led by @pryprk.bsky.social !
Reposted by Shane Liddelow
Astrocyte networks are much larger than previously thought, which “flips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/astrocytes/a...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/astrocytes/a...
September 4, 2025 at 8:50 PM
Astrocyte networks are much larger than previously thought, which “flips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/astrocytes/a...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/astrocytes/a...
Great story in the @thetransmitter.bsky.social today by
@callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks.
Read the story here: www.thetransmitter.org/astrocytes/a...
Read the preprint here: www.biorxiv.org/content/10.1...
@callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks.
Read the story here: www.thetransmitter.org/astrocytes/a...
Read the preprint here: www.biorxiv.org/content/10.1...
Astrocyte networks span large swaths of brain
The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.
www.thetransmitter.org
September 3, 2025 at 1:39 PM
Great story in the @thetransmitter.bsky.social today by
@callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks.
Read the story here: www.thetransmitter.org/astrocytes/a...
Read the preprint here: www.biorxiv.org/content/10.1...
@callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks.
Read the story here: www.thetransmitter.org/astrocytes/a...
Read the preprint here: www.biorxiv.org/content/10.1...
A fantastic time with an excellent group of trainees at the @neurochemistry.org Advanced School.
Let the conference begin!
Let the conference begin!
August 18, 2025 at 2:28 AM
A fantastic time with an excellent group of trainees at the @neurochemistry.org Advanced School.
Let the conference begin!
Let the conference begin!
are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social?
LAST WEEK TO APPLY to be a SPiNES speaker for our next season.
Details and apply here: med.nyu.edu/departments-...
COME AND WOW US!
LAST WEEK TO APPLY to be a SPiNES speaker for our next season.
Details and apply here: med.nyu.edu/departments-...
COME AND WOW US!
a black and white photo of a crowd of people standing and sitting in chairs .
ALT: a black and white photo of a crowd of people standing and sitting in chairs .
media.tenor.com
August 15, 2025 at 7:57 PM
are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social?
LAST WEEK TO APPLY to be a SPiNES speaker for our next season.
Details and apply here: med.nyu.edu/departments-...
COME AND WOW US!
LAST WEEK TO APPLY to be a SPiNES speaker for our next season.
Details and apply here: med.nyu.edu/departments-...
COME AND WOW US!
The American Society for Neurochemistry (ASN) and the International Society for Neurochemistry (ISN) are hosting a discussion on autism, with clinical, research, family, & pharma perspectives.
August 17, 2025
2-4 PM
Hunter College, West Room 714
FREE
Registration recommended: lnkd.in/dJY7hp-b
August 17, 2025
2-4 PM
Hunter College, West Room 714
FREE
Registration recommended: lnkd.in/dJY7hp-b
August 13, 2025 at 2:47 PM
The American Society for Neurochemistry (ASN) and the International Society for Neurochemistry (ISN) are hosting a discussion on autism, with clinical, research, family, & pharma perspectives.
August 17, 2025
2-4 PM
Hunter College, West Room 714
FREE
Registration recommended: lnkd.in/dJY7hp-b
August 17, 2025
2-4 PM
Hunter College, West Room 714
FREE
Registration recommended: lnkd.in/dJY7hp-b
#GliaPapers #GliaAugust2025 @wiley.com
AUGUST COVER
Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)
AUGUST COVER
Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)
August 13, 2025 at 2:20 PM
#GliaPapers #GliaAugust2025 @wiley.com
AUGUST COVER
Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)
AUGUST COVER
Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)
Reposted by Shane Liddelow
Astrocytes connect specific brain regions through plastic gap junctional networks https://www.biorxiv.org/content/10.1101/2025.07.18.665573v1
July 22, 2025 at 7:15 PM
Astrocytes connect specific brain regions through plastic gap junctional networks https://www.biorxiv.org/content/10.1101/2025.07.18.665573v1