lama-awada.bsky.social
@lama-awada.bsky.social
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Rounding out the session is Tom Le Voyer from Institut Imagine.

He is discussing "NF-kB, Thymus and autoimmunity", exploring the critical signaling pathways that prevent our immune system from turning against itself. 📉🦠

That wraps up this week's talks! See you next week! 👏
February 12, 2026 at 12:36 PM
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Next on stage is Gonçalo Nogueira from @pasteur.fr

His talk, "Embryonic thymocyte-epithelial cell interaction plays an essential role in the establishment of adult T cell tolerance," highlights how early development shapes our immune system's future in the context of the thymus. 🧬🛡️
February 12, 2026 at 12:29 PM
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Now, a more detailed look at the ATO system within T-ALL! 🔍

Valentine Louis (INEM) and Clarisse Godard (Institut Saint-Louis) are presenting "Modeling human leukemia using a 3D ATO (Artificial Thymic Organoid) system."
February 12, 2026 at 12:19 PM
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🧪 We are kicking off this week’s MAGIC meeting! First up is @guillaumeandrieu.bsky.social from @inem-necker.bsky.social (Normal & Pathological Lymphoid Differentiation Lab).

He is presenting "Leukemia on ChIP: application," diving into new methodologies for understanding leukemia. 🔬 🧵👇
February 12, 2026 at 12:11 PM
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Happening now at Institut Imagine! 🏛️✨

Prof. Anna Kajaste-Rudnitski (Univ. of Pavia) is on stage dissecting the "double-edged sword" of innate immunity. ⚔️🧬

She is explaining how the same mechanisms that protect us from viruses can block gene therapies and drive CNS inflammation.
February 9, 2026 at 12:24 PM
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Wrapping up with Emmanuelle Six on Gene Therapy. 🧬
Chronic inflammation "exhausts" our blood stem cells (HSPCs), making them less fit for genetic engineering. Emmanuelle is sharing solutions to protect stem cell fitness, ensuring that life-saving gene therapies work better and last longer. 🧪
February 5, 2026 at 12:39 PM
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Thiago Trovati is discussing a creative approach to Sickle Cell Disease (SCD): drug repurposing. 🔄

Focusing on Acute Chest Syndrome (a life-threatening complication), he’s exploring how drugs like tocilizumab, might help SCD patients by addressing ineffective erythropoiesis.🩸 #Hematology #SCD
February 5, 2026 at 12:34 PM
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Deep dive into the gut with David Skurnik (INEM). He has identified Oxalyl-CoA decarboxylase as a critical "survival tool" for Adherent Invasive E. coli (AIEC) in the harsh, acidic environment of the inflamed gut. 🦠
February 5, 2026 at 12:32 PM
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Next, Marie Louise Frémond talking about interferonopathies. These rare genetic disorders are driven by an "overdose" of type I interferon.
She's highlighting the efficacy of Anifrolumab—an IFNAR1 receptor blocker. Results show a significant "normalization" of the interferon signature in patients. 💊
February 5, 2026 at 12:12 PM
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📢 Kicking off today’s MAGIC meeting: Jean-François Gautier (Lariboisière) is discussing the shift in how we view Type 2 Diabetes, not just as a metabolic disorder, but as a chronic inflammatory disease. 🧬
February 5, 2026 at 12:04 PM
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🧬 Advancing Research in Paris with the Region's First AVITI24™ (Element Biosciences) !

We are thrilled to announce that Institut Imagine has officially acquired the first AVITI24 system in Paris.
February 2, 2026 at 4:30 PM
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🔬 Que se passe-t-il vraiment derrière une découverte scientifique ?

Le vendredi 6 mars 2026, l’Institut Imagine vous invite à participer à une rencontre d'une demi-journée sur le thème : « Qu’est-ce que la Recherche à l’Institut Imagine ? »

📌 Inscriptions : yji1wvqwixz.typeform.com/to/spGbo2dC
January 27, 2026 at 8:19 AM
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Live at our weekly seminar: Prof. Chantal Pichon (Univ. Orléans) on the design of imidazolium lipid-based LNPs for mRNA delivery. 🧬

These LNPs use pH-responsive headgroups to improve cytosolic release for cancer vaccines & immune cell engineering. The future of nanomedicine! 🧪🎯 #mRNA #LNP
February 2, 2026 at 12:36 PM
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1/ We are excited to share our new report in PNAS: all three cases of encephalitis triggered by the live-attenuated chikungunya (CHIKV) vaccine (IXCHIQ®) are due to pre-existing autoantibodies neutralizing type I IFN (AAN-I-IFN) (doi.org/10.1073/pnas...).
January 26, 2026 at 9:30 PM
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Closing today's session is Amine Toubal (INEM).
He is decoding the immunometabolic pathways that govern wound healing in Type 2 diabetes. Crucial work for understanding complications in metabolic disorders. 🩹🍬
That’s a wrap for this week’s meeting! See you all next week for more science!
January 22, 2026 at 12:48 PM
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Next, we are looking at the lungs with Mairead Aubert (INEM). 🫁
Her talk focuses on the "Metabolic Control of Airway Epithelial Repair," specifically in the context of Cystic Fibrosis and beyond. Understanding repair mechanisms is key! 🌬️
January 22, 2026 at 12:36 PM
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Welcoming Lucie Peduto from @pasteur.fr! 🏛️
She is diving into the role of stromal lineages in tissue homeostasis and disease. A fascinating look at the structural support systems of our biology.
#biology #research
January 22, 2026 at 12:23 PM
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We are live for our weekly scientific meeting! 🧪
First up, Pierre Isnard from @inem-necker.bsky.social is presenting on HNF1B.
He is discussing how this factor integrates signals that drive failed repair and the progression of kidney disease. Critical insights into renal pathophysiology. 🩺
January 22, 2026 at 12:15 PM
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En 2026, continuons à faire avancer une recherche qui change des vies.

En ce début d’année, je vous adresse mes vœux les plus sincères. Merci à toutes celles et ceux qui nous soutiennent et nous font confiance.

Voir la vidéo : youtu.be/dVpBP92F2FI
Voeux de la Pr Bana Jabri, Directrice générale de l'Institut Imagine
YouTube video by Institut Imagine
youtu.be
January 19, 2026 at 4:28 PM
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🦠 Closing our session is @manusingh.bsky.social discussing the "Long Shadow of Viral Infections".
He's showing how HIV & EBV can reactivate persistent, ancient Endogenous Retroviral proteins. A powerful reminder that our genome's history still dictates our health today!🧬
January 15, 2026 at 1:04 PM
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Moving to autoimmunity with Anaïs Levescot 🛡️
Her talk focuses on somatic clonal evolution of tissue-resident lymphocytes in chronic autoimmunity. Takeaway: Chronic activation isn't just inflammation, it's a pathogenic continuum where somatic mutations drive tissue damage and treatment resistance. 🧬
January 15, 2026 at 12:27 PM
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Next, Katrina Podsypanina (B. Manoury Lab, @inem-necker.bsky.social ) takes the stage to discuss a fascinating evolutionary link. She is exploring how Ancient Endogenous Retroviruses might be the missing link between maternal tolerance and how tumors evade the immune system. 🤰🧪
January 15, 2026 at 12:21 PM
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📢 We are live for our weekly scientific meeting! First up is Fabian Zanchetta (O. Hermine Lab) tackling "Unexplained Erythrocytosis." 🩸
Using the Dr. Warehouse clinical database, they are identifying new genetic drivers for patients with high red blood cell counts. 📉🔍
January 15, 2026 at 12:09 PM
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Pour la Pr Bana Jabri, investir dans la science est un choix essentiel pour notre santé et notre économie.

📖 Retrouvez l'entretien complet dans Le Figaro : sante.lefigaro.fr/medecine/pr-...
January 13, 2026 at 3:23 PM