Kamil Lisek
@klisek.bsky.social
Breast Cancer Biology, PhD, Lab of Nikolaus Rajewsky, MDC, BIMSB, Berlin
A collaborative effort: 🇩🇪 🇵🇱 🇫🇷 🇮🇹 🇬🇷 🇮🇱 🇷🇴 🇵🇹 🇨🇭
Many thanks to the whole
@N_Rajewsky lab,
@nukappa.bsky.social,
@danilexn.bsky.social, our institutions
@mdc-bimsb.bsky.social, @mdc-berlin.bsky.social, and personally to @DeutscheKrebshilfe for their generous support.
Many thanks to the whole
@N_Rajewsky lab,
@nukappa.bsky.social,
@danilexn.bsky.social, our institutions
@mdc-bimsb.bsky.social, @mdc-berlin.bsky.social, and personally to @DeutscheKrebshilfe for their generous support.
July 22, 2025 at 9:48 AM
A collaborative effort: 🇩🇪 🇵🇱 🇫🇷 🇮🇹 🇬🇷 🇮🇱 🇷🇴 🇵🇹 🇨🇭
Many thanks to the whole
@N_Rajewsky lab,
@nukappa.bsky.social,
@danilexn.bsky.social, our institutions
@mdc-bimsb.bsky.social, @mdc-berlin.bsky.social, and personally to @DeutscheKrebshilfe for their generous support.
Many thanks to the whole
@N_Rajewsky lab,
@nukappa.bsky.social,
@danilexn.bsky.social, our institutions
@mdc-bimsb.bsky.social, @mdc-berlin.bsky.social, and personally to @DeutscheKrebshilfe for their generous support.
🎯 Tumor-derived TGFβ initiated TME remodeling: → iCAFs → macrophage recruitment
💪 Later, myCAFs remodeled ECM & interacted with EMT tumor cells
These niches are conserved in human TNBC PDXs and functionally validated.
💪 Later, myCAFs remodeled ECM & interacted with EMT tumor cells
These niches are conserved in human TNBC PDXs and functionally validated.
July 22, 2025 at 9:48 AM
🎯 Tumor-derived TGFβ initiated TME remodeling: → iCAFs → macrophage recruitment
💪 Later, myCAFs remodeled ECM & interacted with EMT tumor cells
These niches are conserved in human TNBC PDXs and functionally validated.
💪 Later, myCAFs remodeled ECM & interacted with EMT tumor cells
These niches are conserved in human TNBC PDXs and functionally validated.
📸 Tumor and stromal cells form spatially organized neighborhoods.
Aligning tumors by progression revealed how cell states, signaling, and ECM features remodel dynamically at the tumor–stroma interface.
Aligning tumors by progression revealed how cell states, signaling, and ECM features remodel dynamically at the tumor–stroma interface.
July 22, 2025 at 9:48 AM
📸 Tumor and stromal cells form spatially organized neighborhoods.
Aligning tumors by progression revealed how cell states, signaling, and ECM features remodel dynamically at the tumor–stroma interface.
Aligning tumors by progression revealed how cell states, signaling, and ECM features remodel dynamically at the tumor–stroma interface.
🐁 Our model develops asynchronous tumors across glands. Using Open-ST and snRNA-seq, we profiled 100+ ducts in situ and treated them as replicates reconstructing tumor evolution from healthy tissue to invasion in native context.
July 22, 2025 at 9:48 AM
🐁 Our model develops asynchronous tumors across glands. Using Open-ST and snRNA-seq, we profiled 100+ ducts in situ and treated them as replicates reconstructing tumor evolution from healthy tissue to invasion in native context.
it is not β-Catenin but rather a mysterious gene called CTNNB1 :D
February 10, 2025 at 10:46 AM
it is not β-Catenin but rather a mysterious gene called CTNNB1 :D