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Kidney International

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Commentary
Metabolic heavyweight: thick ascending limb or proximal tubule? Next round
✍️Kevin A Hurtado and Leslie S. Gewin

doi.org/10.1016/j.kint.2025.08.010

Original article: doi.org/10.1016/j.kint.2025.07.021

#MedSky #NephSky @washunephrology.bsky.social #aki #acutekidneyinjury

November 21, 2025 at 9:55 PM

Kidney International

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Commentary
Underappreciated hard worker: resident macrophage patrols and controls local inflammation in kidney
✍️Ryo Yamada and Motoko Yanagita

doi.org/10.1016/j.kint.2025.08.005

Original article: doi.org/10.1016/j.kint.2025.07.022

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November 21, 2025 at 9:44 PM

Kidney International

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A national cohort study examined the risk of severe infection and infection-related mortality in patients with chronic kidney disease with lupus nephritis in comparison to other chronic kidney disease etiologies

doi.org/10.1016/j.kint.2025.10.010

#OpenAccess #MedSky #NephSky #ckd @ki.se

November 21, 2025 at 9:36 PM

Kidney International

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Renal hemosiderosis secondary to intravascular hemolytic anemia

doi.org/10.1016/j.kint.2025.05.033

🔹Rare case of secondary renal hemosiderosis after valve surgery
🔹Beautiful histology, Prussian blue, and EM images showing hemosiderin deposit

#MedSky #NephSky @umontreal-en.bsky.social

November 20, 2025 at 7:25 PM

Kidney International

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Commentary
Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health

Mitchell A Sullivan and Josephine M Forbes

doi.org/10.1016/j.kint.2025.08.006

Original article: doi.org/10.1016/j.kint.2025.06.018

#NephSky #MedSky #kidneydisease

November 20, 2025 at 7:13 PM

Kidney International

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KI Commentary
The coming of age for polycystic kidney disease
Uyen A. Tran and Olivier Wessely

doi.org/10.1016/j.kint.2025.08.001

Original article: doi.org/10.1016/j.kint.2025.05.027

#ADPKD #NephSky #MedSky @clevelandclinic.bsky.social @casewestern.bsky.social

November 20, 2025 at 6:43 PM

Kidney International

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Early diagnosis of #POEMSsyndrome prompted by skin findings and bone window computed tomography

doi.org/10.1016/j.kint.2025.05.032

🔹This case demonstrates the importance of subtle skin findings and imaging interpretation in rare disease diagnosis.

#NephSky #MedSky #kidneydisease

November 13, 2025 at 9:13 PM

Kidney International

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REMODELing Mechanistic Trials for Kidney Disease: a multi-modal, tissue-centered approach to understand the renal mechanism of action of #semaglutide

doi.org/10.1016/j.kint.2025.10.005

#OpenAccess #MedSky #NephSky #CKD #diabetes @uwnephrology.bsky.social @umich.edu @kidney-resrch-inst.bsky.social

November 12, 2025 at 6:32 PM

Kidney International

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From progression to remission: a new paradigm for success in chronic kidney disease

doi.org/10.1016/j.kint.2025.10.004

@georgeinstitute.bsky.social @um-radyfhs.bsky.social
@uhn.ca @utoronto.ca @kidney-resrch-inst.bsky.social @uwnephrology.bsky.social

#OpenAccess #MedSky #NephSky #ckd #gfr

November 12, 2025 at 6:30 PM

Kidney International

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Peripheral blood smear as a diagnostic clue to type I cryoglobulinemia

doi.org/10.1016/j.kint.2025.05.031

#Cryoglobulinemia should be considered in the differential diagnosis of rapidly progressive renal failure even in the absence of cutaneous manifestations.
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November 12, 2025 at 6:26 PM

Kidney International

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Dual-Antigen Membranous Nephropathy

doi.org/10.1016/j.kint.2025.10.006

#NephSky #MedSky #membranousnephropathy @mayoclinicpath.bsky.social @arkanalabs.bsky.social @lynncornell.bsky.social @aaronstorey.bsky.social

November 4, 2025 at 10:16 PM

Kidney International

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Mouse Alport podocytes are susceptible to AAV9 transduction in vivo

doi.org/10.1016/j.kint.2025.09.027

#MedSky #NephSky
@jeffminerphd.bsky.social @washunephrology.bsky.social @washumedicine.bsky.social

November 4, 2025 at 6:05 PM

Kidney International

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Preclinical evaluation of antigen-specific B-cell depletion for phospholipase A2 receptor membranous nephropathy with chimeric autoantibody receptor T-cells

doi.org/10.1016/j.kint.2025.09.028

#NephSky #MedSky @columbiauniversity.bsky.social @pennmedicine.bsky.social

November 4, 2025 at 5:55 PM

Kidney International

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Sodium glucose cotransporter 2 inhibition does not improve active lupus nephritis in MRLlpr/lpr mice

doi.org/10.1016/j.kint.2025.09.026

#NephSky #MedSky #lupus #nupusnephritis #kidneydisease
@vhir.bsky.social @lmumuenchen.bsky.social @hjanders.bsky.social @pepasolerr.bsky.social

October 31, 2025 at 8:40 PM

Kidney International

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Single-cell spatial transcriptomics reveal intraglomerular cell activation and ligand-receptor relationships in chronic, active antibody mediated rejection

doi.org/10.1016/j.kint.2025.08.042

#MedSky #NephSky @harvardmed.bsky.social

October 31, 2025 at 8:17 PM

Kidney International

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Mini Review
Optimizing symptom management in people with kidney failure

doi.org/10.1016/j.kint.2025.07.040

#KIReview #hemodialysis #NephSky #MedSky #kidneyfailure @sydney.edu.au

October 28, 2025 at 8:22 PM

Kidney International

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Advances in computational #nephropathology

doi.org/10.1016/j.kint.2025.06.029

#OpenAccess #NephSky #MedSky #kidneybiopsy #PathSky
@rbuelow.bsky.social @rwth.bsky.social

🌟Find more articles in our Review Series: Big Science, AI, and Machine Learning:
www.kidney-international.org/content/bigs...

October 22, 2025 at 5:55 PM

Kidney International

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Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function

doi.org/10.1016/j.kint.2025.08.0

#OpenAccess #MedSky #NephSky #kidneydisease #GWAS @uniklinik-fr.bsky.social @columbiakidney.bsky.social @columbiauniversity.bsky.social @kirylukk.bsky.social

October 22, 2025 at 4:05 PM

Kidney International

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Executive summary of the #KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (#IgAN) and Immunoglobulin A Vasculitis (#IgAV)

doi.org/10.1016/j.kint.2025.04.003

#OpenAccess #MedSky #NephSky @kdigo.org

October 21, 2025 at 6:53 PM

Kidney International

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A randomized controlled trial evaluated the effect of pravastatin on kidney disease outcomes in adult patients with early-stage #autosomaldominantpolycystickidneydisease

doi.org/10.1016/j.kint.2025.08.037

@childrensphila.bsky.social @unmhsc.bsky.social @cumedicalschool.bsky.social #MedSky #NephSky

October 21, 2025 at 6:23 PM

Kidney International

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Commentary
Where next for potassium binders in hemodialysis?
KS Ravi and FR McCausland
doi.org/10.1016/j.kint.2025.07.018

Original article doi.org/10.1016/j.kint.2025.06.016

#MedSky #NephSky #CKD #chronickidneydisease #hemodialysis #cardiovasculardisease #CVD

October 20, 2025 at 1:23 PM

Kidney International

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Inactivation of Pkd2 in adult mice results in delayed cyst formation and identifies sex as a major modifier of disease severity.

doi.org/10.1016/j.kint.2025.08.039

#OpenAccess #NephSky #MedSky #ADPKD #ESKD