Kassiani Panagiotou
@kassipan.bsky.social
PhD candidate @Ettema lab | Laboratory of Microbiology (WUR)
Check out this beautiful work led by @stephkoe.bsky.social, with great teamwork from @danieltamarit.bsky.social and @ettema.bsky.social :
💻 github.com/stephkoest/w...
📄 doi.org/10.1101/2025.07.14.663642
💻 github.com/stephkoest/w...
📄 doi.org/10.1101/2025.07.14.663642
GitHub - stephkoest/witchi: A compositional bias testing and pruning tool for multiple sequence alignments
A compositional bias testing and pruning tool for multiple sequence alignments - stephkoest/witchi
github.com
July 20, 2025 at 4:58 PM
Check out this beautiful work led by @stephkoe.bsky.social, with great teamwork from @danieltamarit.bsky.social and @ettema.bsky.social :
💻 github.com/stephkoest/w...
📄 doi.org/10.1101/2025.07.14.663642
💻 github.com/stephkoest/w...
📄 doi.org/10.1101/2025.07.14.663642
🧂The placement of halophilic lineages was restored — Methanonatronarchaeia emerged outside Halobacteria, supporting independent origins of halophily
(in agreement with targeted analyses: doi.org/10.1038/s415... &
doi.org/10.1038/s415...)
(in agreement with targeted analyses: doi.org/10.1038/s415... &
doi.org/10.1038/s415...)
July 20, 2025 at 4:58 PM
🧂The placement of halophilic lineages was restored — Methanonatronarchaeia emerged outside Halobacteria, supporting independent origins of halophily
(in agreement with targeted analyses: doi.org/10.1038/s415... &
doi.org/10.1038/s415...)
(in agreement with targeted analyses: doi.org/10.1038/s415... &
doi.org/10.1038/s415...)
🧩 Phyla representing the clades Acherontia and Stygia (Methanobacteriota_B + Hadarchaeota) shifted to sister TACK + Asgardarchaeota — consistent with site-heterogeneous models (doi.org/10.1186/s128...).
July 20, 2025 at 4:58 PM
🧩 Phyla representing the clades Acherontia and Stygia (Methanobacteriota_B + Hadarchaeota) shifted to sister TACK + Asgardarchaeota — consistent with site-heterogeneous models (doi.org/10.1186/s128...).
Among the topological improvements:
🔥Thermophilic clades (e.g. JANJXX01, DRAE01, Korarchaeia) were repositioned in line with recent phylogenomic studies (doi.org/10.1038/s415... &
doi.org/10.1101/2025...).
🔥Thermophilic clades (e.g. JANJXX01, DRAE01, Korarchaeia) were repositioned in line with recent phylogenomic studies (doi.org/10.1038/s415... &
doi.org/10.1101/2025...).
July 20, 2025 at 4:58 PM
Among the topological improvements:
🔥Thermophilic clades (e.g. JANJXX01, DRAE01, Korarchaeia) were repositioned in line with recent phylogenomic studies (doi.org/10.1038/s415... &
doi.org/10.1101/2025...).
🔥Thermophilic clades (e.g. JANJXX01, DRAE01, Korarchaeia) were repositioned in line with recent phylogenomic studies (doi.org/10.1038/s415... &
doi.org/10.1101/2025...).
→ The number of biased taxa dropped from 95.1% to just 2.3%
→ Pruning automatically stopped once further trimming risked loss of phylogenetic signal
Discrepancy between observed and expected amino acid frequencies in taxa:
→ Pruning automatically stopped once further trimming risked loss of phylogenetic signal
Discrepancy between observed and expected amino acid frequencies in taxa:
July 20, 2025 at 4:58 PM
→ The number of biased taxa dropped from 95.1% to just 2.3%
→ Pruning automatically stopped once further trimming risked loss of phylogenetic signal
Discrepancy between observed and expected amino acid frequencies in taxa:
→ Pruning automatically stopped once further trimming risked loss of phylogenetic signal
Discrepancy between observed and expected amino acid frequencies in taxa: