Jonathan Zuckerman MD PhD
@jzrenalpath.bsky.social
Service Chief, Renal Pathology, UCLA Department of Pathology and Laboratory Medicine. Views are my own.
SAP is positive as well:
November 21, 2025 at 3:03 PM
SAP is positive as well:
It's an antigen retrieval step for parrafin IF: pubmed.ncbi.nlm.nih.gov/17063172/
Immunofluorescence on pronase-digested paraffin sections: a valuable salvage technique for renal biopsies - PubMed
Direct immunofluorescence (IF) on frozen tissue is the method of choice for the study of medical renal diseases. When no glomeruli are available, IF can be performed on the formalin-fixed paraffin-embedded tissue allocated for light microscopy after antigen retrieval with proteases. In this study, t …
pubmed.ncbi.nlm.nih.gov
November 20, 2025 at 4:13 PM
It's an antigen retrieval step for parrafin IF: pubmed.ncbi.nlm.nih.gov/17063172/
Typically occurs in young women with vague autoimmune history. Has not been associated with MGUS, plasma cell dyscrasias, or lymphomas. Deposits + for SAP. See references here: . doi.org/10.1038/ki.2...
doi.org/10.1016/j.ki... doi.org/10.1016/j.ek...
doi.org/10.1016/j.ki... doi.org/10.1016/j.ek...
Redirecting
doi.org
November 20, 2025 at 1:01 PM
Typically occurs in young women with vague autoimmune history. Has not been associated with MGUS, plasma cell dyscrasias, or lymphomas. Deposits + for SAP. See references here: . doi.org/10.1038/ki.2...
doi.org/10.1016/j.ki... doi.org/10.1016/j.ek...
doi.org/10.1016/j.ki... doi.org/10.1016/j.ek...