Julian Trouillon
@juliantrouillon.bsky.social
SNSF Ambizione group leader at ETH Zürich. Bacterial transcription factors 🧬
🥳 New preprint! 🥳
While planning molecular screening experiments, we went deep down a rabbit hole on group testing strategies to improve throughput. We present PoolPy, a tool to facilitate the design of pooled experiments.
This is still preliminary, happy to take feedback!
arxiv.org/abs/2509.03481
While planning molecular screening experiments, we went deep down a rabbit hole on group testing strategies to improve throughput. We present PoolPy, a tool to facilitate the design of pooled experiments.
This is still preliminary, happy to take feedback!
arxiv.org/abs/2509.03481
PoolPy: Flexible Group Testing Design for Large-Scale Screening
In large screening campaigns, group testing can greatly reduce the number of tests needed when compared to testing each sample individually. However, choosing and applying an appropriate group testing...
arxiv.org
October 6, 2025 at 11:30 AM
🥳 New preprint! 🥳
While planning molecular screening experiments, we went deep down a rabbit hole on group testing strategies to improve throughput. We present PoolPy, a tool to facilitate the design of pooled experiments.
This is still preliminary, happy to take feedback!
arxiv.org/abs/2509.03481
While planning molecular screening experiments, we went deep down a rabbit hole on group testing strategies to improve throughput. We present PoolPy, a tool to facilitate the design of pooled experiments.
This is still preliminary, happy to take feedback!
arxiv.org/abs/2509.03481
🥳 New paper out!
In this work, we identified small molecule effectors modulating the activity of transcription factors in E. coli.
Using metabolomics + transcriptomics, we could parse the entire regulatory network and predict signal molecules for 41 TFs!
www.embopress.org/doi/full/10....
In this work, we identified small molecule effectors modulating the activity of transcription factors in E. coli.
Using metabolomics + transcriptomics, we could parse the entire regulatory network and predict signal molecules for 41 TFs!
www.embopress.org/doi/full/10....
Predicting input signals of transcription factors in Escherichia coli | Molecular Systems Biology
imageimageThis study developed a systematic workflow leveraging transcriptomics and metabolomics
to identify input signals for 41 transcription factors in E. coli. A systematic workflow was developed...
www.embopress.org
September 1, 2025 at 1:54 PM
🥳 New paper out!
In this work, we identified small molecule effectors modulating the activity of transcription factors in E. coli.
Using metabolomics + transcriptomics, we could parse the entire regulatory network and predict signal molecules for 41 TFs!
www.embopress.org/doi/full/10....
In this work, we identified small molecule effectors modulating the activity of transcription factors in E. coli.
Using metabolomics + transcriptomics, we could parse the entire regulatory network and predict signal molecules for 41 TFs!
www.embopress.org/doi/full/10....
Reposted by Julian Trouillon
Check out our latest preprint where we show synergistic interactions between bacteria for the degradation of complex polysaccharides 🌊🦠🔺
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
A division of labor controls the degradation of fucoidans in the ocean
Fucoidans, complex polysaccharides produced by brown algae and diatoms, contribute to long-term carbon sequestration due to their resistance to microbial degradation1,2. While individual microbes can ...
www.biorxiv.org
August 14, 2025 at 11:32 AM
Check out our latest preprint where we show synergistic interactions between bacteria for the degradation of complex polysaccharides 🌊🦠🔺
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...
Reposted by Julian Trouillon
We are searching for a postdoc in Marine Phytoplankton Metabolism and Carbon Storage! You'll get the chance to work in Belgium to combine high-throughput metabolomics and enzymes to study how microbes naturally sequester atmospheric carbon in organic marine molecules!
t.co/orCCyZhzeh
t.co/orCCyZhzeh
March 13, 2025 at 6:49 AM
We are searching for a postdoc in Marine Phytoplankton Metabolism and Carbon Storage! You'll get the chance to work in Belgium to combine high-throughput metabolomics and enzymes to study how microbes naturally sequester atmospheric carbon in organic marine molecules!
t.co/orCCyZhzeh
t.co/orCCyZhzeh
I have an open Postdoc position in Molecular Systems Biology at ETH Zürich!
The project is about the conservation of transcription factors functions between strains of Pseudomonas aeruginosa 🧬🦠
More details and application at:
jobs.ethz.ch/job/view/JOP...
Please share!
The project is about the conservation of transcription factors functions between strains of Pseudomonas aeruginosa 🧬🦠
More details and application at:
jobs.ethz.ch/job/view/JOP...
Please share!
Postdoctoral Position in Molecular Systems Biology
jobs.ethz.ch
December 6, 2024 at 3:20 PM
I have an open Postdoc position in Molecular Systems Biology at ETH Zürich!
The project is about the conservation of transcription factors functions between strains of Pseudomonas aeruginosa 🧬🦠
More details and application at:
jobs.ethz.ch/job/view/JOP...
Please share!
The project is about the conservation of transcription factors functions between strains of Pseudomonas aeruginosa 🧬🦠
More details and application at:
jobs.ethz.ch/job/view/JOP...
Please share!