Thank you @ghazeskandari.bsky.social !

Wonderful collaborators supported this work, Steve Lacroix, @bradleykerr.bsky.social, and @markcembrowski.bsky.social!

Funding from @nserc-resnet.bsky.social

Surprisingly, in transgenic mice with more developmental microglia proliferation, CSF1 and IL34 were unchanged, meaning that other factors are involved in regulating microglia proliferation.

To get at this, Brady tested many factors and found that only CSF1R ligands like CSF1 and IL34 promote microglia proliferation. Both CSF1 and IL34 are found in the developing brain to regulate microglia proliferation.

A special thanks to Rebecca John who did such a great job with this project. Also for the funding from International Spinal Research Fund and the Christopher and Dana Reeve Foundation with support CIHR and CRC